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Reflection phase imaging provides label-free, high-resolution characterization of biological samples, typically using interferometric-based techniques. Here, we investigate reflection phase microscopy from intensity-only measurements under…

Quantitative Methods · Quantitative Biology 2019-12-18 Alex Matlock , Anne Sentenac , Patrick C. Chaumet , Ji Yi , Lei Tian

In conventional tomographic reconstruction, the pre-processing step includes flat-field correction, where each sample projection on the detector is divided by a reference image taken without the sample. When using coherent X-rays as probe,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Viktor Nikitin , Marcus Carlsson , Doga Gursoy , Rajmund Mokso , Peter Cloetens

Recently Fourier Ptychography (FP) has attracted great attention, due to its marked effectiveness in leveraging snapshot numbers for spatial resolution in large field-of-view imaging. To acquire high signal-to-noise-ratio (SNR) images under…

Optics · Physics 2015-02-19 Liheng Bian , Jinli Suo , Guoan Zheng , KaiKai Guo , Feng Chen , Qionghai Dai

Image Phase Alignment Super-sampling (ImPASS) is a computational method for combining displaced low-resolution images into a single high-resolution image. The general steps include measuring the relative displacements, up-sampling, aligning…

Optics · Physics 2026-01-09 James N. Caron

X-ray phase-contrast imaging has the potential to improve image contrast with lower dose by probing an object's refractive properties as well as its absorptive properties. To reconstruct a phase-contrast image from a raw dataset, a phase…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

Deconvolution phase microscopy enables high-contrast visualization of transparent samples through reconstructions of their transmitted phases or refractive indexes. Herein, we propose a method to extend 2D deconvolution phase microscopy to…

Optics · Physics 2022-04-20 Herve Hugonnet , Mahn Jae Lee , Yongkeun Park

By circumventing the resolution limitations of optics, coherent diffractive imaging (CDI) and ptychography are making their way into scientific fields ranging from X-ray imaging to astronomy. Yet, the need for time consuming iterative phase…

Computational Physics · Physics 2023-10-13 Oliver Hoidn , Aashwin Ananda Mishra , Apurva Mehta

X-ray ptychography has revolutionised nanoscale phase contrast imaging at large-scale synchrotron sources in recent years. We present here the first successful demonstration of the technique in a small-scale laboratory setting. We conducted…

Iterative ptychographic reconstruction algorithms are widely used for coherent diffractive imaging but can exhibit slow convergence under realistic experimental conditions. We propose a machine learning-augmented approach that accelerates…

Ptychographic imaging at synchrotron and XFEL sources requires dense overlapping scans, limiting throughput and increasing dose. Extending coherent diffractive imaging to overlap-free operation on extended samples remains an open problem.…

Optics · Physics 2026-05-01 Oliver Hoidn , Albert Vong , Aashwin Mishra , Steven Henke , Matthew Seaberg

X-ray imaging allows for a non-invasive image of the internal structure of an object. The most common form of X-ray imaging, projectional radiography, is simply a projection or "shadow" of the object rather than a point-to-point image…

Optics · Physics 2020-10-15 Thomas A. Smith , Zhehui Wang , Yanhua Shih

Acousto-optic imaging (AOI) enables optical-contrast imaging deep inside scattering samples via localized ultrasound-modulation of scattered light. While AOI allows optical investigations at depths, its imaging resolution is inherently…

Optics · Physics 2021-01-26 Moriya Rosenfeld , Daniel Doktofsky , Gil Weinberg , Yunzhe Li , Lei Tian , Ori Katz

In this work, we propose a new segmentation algorithm for images containing convex objects present in multiple shapes with a high degree of overlap. The proposed algorithm is carried out in two steps, first we identify the visible contours,…

Computer Vision and Pattern Recognition · Computer Science 2017-11-08 Kumar Abhinav , Jaideep Singh Chauhan , Debasis Sarkar

The use of ray projections to reconstruct images is a common technique in medical imaging. Dealing with incomplete data is particularly important when a patient is vulnerable to potentially damaging radiation or is unable to cope with the…

Neural and Evolutionary Computing · Computer Science 2024-06-04 Mohammad Majid al-Rifaie , Tim Blackwell

As a promising lensless imaging method for distance objects, intensity interferometry imaging (III) had been suffering from the unreliable phase retrieval process, hindering the development of III for decades. Recently, the introduction of…

Optics · Physics 2021-02-11 Yuchen He , Yuan Yuan , Hui Chen , Huaibin Zheng , Jianbin Liu , Zhuo Xu

A widely tested approach to overcoming the diffraction limit in microscopy without disturbing the sample relies on substituting widefield sample illumination with a structured light beam. This gives rise to confocal, image-scanning and…

Optics · Physics 2024-06-03 Alexander Duplinskiy , Jernej Frank , Kaden Bearne , A. I. Lvovsky

Single-Pixel Imaging (SPI) enables the reconstruction of objects using a single detector through sequential illuminations with structured light patterns. The choice of illumination patterns is critical, particularly in highly undersampled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Serban Cristian Tudosie , Alexander Denker , Zeljko Kereta , Simon Arridge

Ptychography has risen as a reference X-ray imaging technique: it achieves resolutions of one billionth of a meter, macroscopic field of view, or the capability to retrieve chemical or magnetic contrast, among other features. A…

Optimization and Control · Mathematics 2019-06-10 Huibin Chang , Pable Enfedaque , Stefano Marchesini

An all optical implementation of pulse reconstruction using time-domain ptychography is demonstrated showing excellent results. Setup and reconstruction are easy to implement and a number of drawbacks found in other second order techniques…

Methods for 3D reconstruction such as Photometric stereo recover the shape and reflectance properties using multiple images of an object taken with variable lighting conditions from a fixed viewpoint. Photometric stereo assumes that a scene…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Anish R. Khadka , Paolo Remagnino , Vasileios Argyriou