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The hardness of combinatorial optimization (CO) problems hinders collecting solutions for supervised learning. However, learning neural networks for CO problems is notoriously difficult in lack of the labeled data as the training is easily…

Machine Learning · Computer Science 2022-07-26 Haoran Sun , Etash K. Guha , Hanjun Dai

Mixed-Integer Linear Programming (MILP) is a cornerstone of combinatorial optimization, yet solving large-scale instances remains a significant computational challenge. Recently, Graph Neural Networks (GNNs) have shown promise in…

Machine Learning · Computer Science 2025-11-13 Tianle Pu , Jianing Li , Yingying Gao , Shixuan Liu , Zijie Geng , Haoyang Liu , Chao Chen , Changjun Fan

The pyLOT library offers a Python implementation of linearized optimal transport (LOT) techniques and methods to use in downstream tasks. The pipeline embeds probability distributions into a Hilbert space via the Optimal Transport maps from…

Machine Learning · Statistics 2025-02-06 Jun Linwu , Varun Khurana , Nicholas Karris , Alexander Cloninger

In neural combinatorial optimization (CO), reinforcement learning (RL) can turn a deep neural net into a fast, powerful heuristic solver of NP-hard problems. This approach has a great potential in practical applications because it allows…

Machine Learning · Computer Science 2021-07-14 Yeong-Dae Kwon , Jinho Choo , Byoungjip Kim , Iljoo Yoon , Youngjune Gwon , Seungjai Min

In this work, we augment reinforcement learning with an inference-time collision model to ensure safe and efficient container management in a waste-sorting facility with limited processing capacity. Each container has two optimal emptying…

Machine Learning · Computer Science 2025-03-24 Abhijeet Pendyala , Tobias Glasmachers

Combinatorial Optimization underpins many real-world applications and yet, designing performant algorithms to solve these complex, typically NP-hard, problems remains a significant research challenge. Reinforcement Learning (RL) provides a…

We present a proximal policy optimization (PPO) agent trained through curriculum learning (CL) principles and meticulous reward engineering to optimize a real-world high-throughput waste sorting facility. Our work addresses the challenge of…

Machine Learning · Computer Science 2024-07-24 Abhijeet Pendyala , Asma Atamna , Tobias Glasmachers

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Machine Learning · Computer Science 2025-09-29 Ziqing Wang , Yibo Wen , William Pattie , Xiao Luo , Weimin Wu , Jerry Yao-Chieh Hu , Abhishek Pandey , Han Liu , Kaize Ding

We study how the lift-and-project procedure applies to the multiparametric analysis of conic linear optimization (CLO) problems. We first introduce the concept of a pair of primal and dual conic representable sets and define the set-valued…

Optimization and Control · Mathematics 2022-12-09 Zi-zong Yan , Xiangjun Li , Jinhai Guo

In the last few decades, Machine Learning (ML) has achieved significant success across domains ranging from healthcare, sustainability, and the social sciences, to criminal justice and finance. But its deployment in increasingly…

Machine Learning · Computer Science 2025-09-03 Nathan Justin , Qingshi Sun , Andrés Gómez , Phebe Vayanos

Machine learning is finding its application in a multitude of areas in science and research, and Climate and Earth Sciences is no exception to this trend. Operational forecasting systems based on data-driven approaches and machine learning…

Machine Learning · Computer Science 2026-01-19 Shahbaz Alvi , Giusy Fedele , Gabriele Accarino , Italo Epicoco , Ilenia Manco , Pasquale Schiano

Neural Combinatorial Optimization (NCO) has emerged as a promising approach for NP-hard problems. However, prevailing RL-based methods suffer from low sample efficiency due to sparse rewards and underused solutions. We propose Best-anchored…

Machine Learning · Computer Science 2025-06-03 Zijun Liao , Jinbiao Chen , Debing Wang , Zizhen Zhang , Jiahai Wang

We present an integrated prediction-optimization (PredOpt) framework to efficiently solve sequential decision-making problems by predicting the values of binary decision variables in an optimal solution. We address the key issues of…

Machine Learning · Computer Science 2023-11-14 Dogacan Yilmaz , İ. Esra Büyüktahtakın

Combinatorial optimization problems (COPs) are an important research topic in various fields. In recent times, there have been many attempts to solve COPs using deep learning-based approaches. We propose a novel neural network model that…

Computational Geometry · Computer Science 2023-04-17 Jaeseung Lee , Woojin Choi , Jibum Kim

Federated Learning (FL) enables decentralized model training across multiple clients without exposing local data, but its distributed feature makes it vulnerable to backdoor attacks. Despite early FL backdoor attacks modifying entire…

Machine Learning · Computer Science 2025-10-23 Kuai Yu , Xiaoyu Wu , Peishen Yan , Qingqian Yang , Linshan Jiang , Hao Wang , Yang Hua , Tao Song , Haibing Guan

Solving NP-hard/complete combinatorial problems with neural networks is a challenging research area that aims to surpass classical approximate algorithms. The long-term objective is to outperform hand-designed heuristics for…

Neural and Evolutionary Computing · Computer Science 2024-02-14 Dobrik Georgiev , Danilo Numeroso , Davide Bacciu , Pietro Liò

Cross-project defect prediction (CPDP) leverages machine learning (ML) techniques to proactively identify software defects, especially where project-specific data is scarce. However, developing a robust ML pipeline with optimal…

Neural and Evolutionary Computing · Computer Science 2024-11-12 Jiaxin Chen , Jinliang Ding , Kay Chen Tan , Jiancheng Qian , Ke Li

Neural Combinatorial Optimization aims to learn to solve a class of combinatorial problems through data-driven methods and notably through employing neural networks by learning the underlying distribution of problem instances. While, so far…

Machine Learning · Computer Science 2025-08-05 Daniela Thyssens , Tim Dernedde , Wilson Sentanoe , Lars Schmidt-Thieme

Nowadays refinery optimization utilizes sheer amounts of data, which can be handled with modern Linear Programming (LP) software, but the interpreting and applying the results remains challenging. Large petrochemical companies use massive…

We present BackboneLearn: an open-source software package and framework for scaling mixed-integer optimization (MIO) problems with indicator variables to high-dimensional problems. This optimization paradigm can naturally be used to…

Machine Learning · Computer Science 2023-11-27 Vassilis Digalakis , Christos Ziakas
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