Related papers: Real-Time Phase Contrast MRI to quantify Cerebral …
Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…
Purpose: The DANTE-SPACE sequence facilitates three-dimensional intracranial vessel wall imaging with simultaneous suppression of blood and cerebrospinal fluid (CSF). However, the achieved image contrast depends closely on the selected…
Atrial fibrillation (AF) is a common cardiac arrhythmia that significantly increases the risk of stroke and heart failure, necessitating reliable and generalizable detection methods from electrocardiogram (ECG) recordings. Although deep…
Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used to visualize brain activation regions by detecting hemodynamic responses associated with increased metabolic demand. While alternative MRI…
Multi-layer diffuse correlation spectroscopy (DCS) models have been developed to reduce the contamination of superficial signals in cerebral blood flow index (CBFi) measurements. However, a systematic comparison of these models and clear…
Coronary angiography is the main tool for assessing coronary artery disease, but visual grading of stenosis is variable and only moderately related to ischaemia. Wire based fractional flow reserve (FFR) improves lesion selection but is not…
Bubbles introduced to the arterial circulation during invasive medical procedures can have devastating consequences for brain function but their effects are currently difficult to quantify. Here we present a Monte-Carlo simulation…
Understanding interactions in complex systems requires capturing the relative timing of coupling, not only its strength. Phase synchronization captures this timing, yet most methods either reduce the phase to its cosine or collapse it into…
Cerebral autoregulation (CA) is a fundamental mechanism that modulates cerebrovascular resistance, primarily by regulating the diameter of small cerebral vessels to maintain stable cerebral blood flow (CBF) in response to fluctuations in…
Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…
Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…
Cone-beam CT (CBCT) is routinely acquired in radiotherapy but suffers from severe artifacts and unreliable Hounsfield Unit (HU) values, limiting its direct use for dose calculation. Synthetic CT (sCT) generation from CBCT is therefore an…
High-fidelity patient-specific modeling of cardiovascular flows and hemodynamics is challenging. Direct blood flow measurement inside the body with in-vivo measurement modalities such as 4D flow magnetic resonance imaging (4D flow MRI)…
Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progression, and clinical diagnosis. Although various in vivo methods have been developed to assess…
Conventional cardiovascular magnetic resonance (CMR) cine imaging relies on binning multiple heartbeats into a single cardiac cycle, which fails in arrhythmic patients where beat-to-beat variability causes motion artifacts and loss of…
Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…
The quality of cardiac magnetic resonance (CMR) imaging is susceptible to respiratory motion artifacts. The model robustness of automated segmentation techniques in face of real-world respiratory motion artifacts is unclear. This manuscript…
Accelerating imaging speed in optical microscopy is often realized at the expense of image contrast, image resolution, and detection sensitivity- a common predicament for advancing high-speed and high-throughput cellular imaging. We here…
Deviations in respiratory rate often precede abnormalities in other vital signs. However, continuously monitoring respiratory rates outside clinical settings remains challenging due to the obtrusive nature and sensitivity to body motions in…
Phase contrast X-ray imaging (PCXI) is an emerging imaging modality that has the potential to greatly improve radiography for medical imaging and materials analysis. PCXI makes it possible to visualise soft-tissue structures that are…