Related papers: Real-Time Phase Contrast MRI to quantify Cerebral …
Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…
Fractional flow reserve (FFR) is the gold standard for diagnosing coronary artery disease (CAD). FFRCT uses computational fluid dynamics (CFD) to evaluate FFR non-invasively by simulating coronary flow in geometries reconstructed from…
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…
Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests,…
To address many of the deficiencies in optical neuroimaging technologies such as poor spatial resolution, time-consuming reconstruction, low penetration depth, and contact-based measurement, a novel, noncontact, time-resolved laser speckle…
A binary beat-by-beat classification algorithm for cerebral blood flow velocity (CBFV) recordings based on amplitude, spectral and morphological features is presented. The classification difference between 15 manually and algorithmically…
Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…
Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…
Purpose: Arterial spin labeling (ASL) perfusion imaging indicates direct and absolute measurement of cerebral blood flow (CBF). Arterial transit time (ATT) is a related physiological parameter reflecting the duration for the labeled spins…
Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF…
ECG-gated cine imaging in breath-hold enables high-quality diagnostics in most patients, arrhythmia and inability to hold breath, however, can severely corrupt outcomes. Real-time cardiac MRI in free-breathing leverages robust and faster…
Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…
The development of neurologically active drugs faces a challenge in treating brain diseases due to the blood-brain barrier's impermeability. High-intensity focused ultrasound can open the barrier in a targeted manner, expanding treatment…
Accurate simulations of the flow in the human airway are essential for advancing diagnostic methods. Many existing computational studies rely on simplified geometries or turbulence models, limiting their simulation's ability to resolve flow…
A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…
Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…
Atrial fibrillation (AF) is the most common form of arrhythmia with accelerated and irregular heart rate (HR), leading to both heart failure and stroke and being responsible for an increase in cardiovascular morbidity and mortality. In…
Aims. Clinical data indicating a heart rate (HR) target during rate control therapy for permanent atrial fibrillation (AF) and assessing its eventual relationship with reduced exercise tolerance are lacking. The present study aims at…
There has recently been growing evidence that atrial fibrillation (AF), the most common cardiac arrhythmia, is independently associated with the risk of dementia. This represents a very recent frontier with high social impact for the number…
Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…