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Trustworthiness is a major prerequisite for the safe application of opaque deep learning models in high-stakes domains like medicine. Understanding the decision-making process not only contributes to fostering trust but might also reveal…

Machine Learning · Computer Science 2025-01-07 Payal Varshney , Adriano Lucieri , Christoph Balada , Andreas Dengel , Sheraz Ahmed

For the past few years, deep generative models have increasingly been used in biological research for a variety of tasks. Recently, they have proven to be valuable for uncovering subtle cell phenotypic differences that are not directly…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Anis Bourou , Thomas Boyer , Kévin Daupin , Véronique Dubreuil , Aurélie De Thonel , Valérie Mezger , Auguste Genovesio

Counterfactual reasoning is often used in clinical settings to explain decisions or weigh alternatives. Therefore, for imaging based specialties such as ophthalmology, it would be beneficial to be able to create counterfactual images,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Indu Ilanchezian , Valentyn Boreiko , Laura Kühlewein , Ziwei Huang , Murat Seçkin Ayhan , Matthias Hein , Lisa Koch , Philipp Berens

Causal generative modelling is gaining interest in medical imaging due to its ability to answer interventional and counterfactual queries. Most work focuses on generating counterfactual images that look plausible, using auxiliary…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Tian Xia , Mélanie Roschewitz , Fabio De Sousa Ribeiro , Charles Jones , Ben Glocker

Obstetric ultrasound image quality is crucial for accurate diagnosis and monitoring of fetal health. However, acquiring high-quality standard planes is difficult, influenced by the sonographer's expertise and factors like the maternal BMI…

Dataset expansion can effectively alleviate the problem of data scarcity for medical image segmentation, due to privacy concerns and labeling difficulties. However, existing expansion algorithms still face great challenges due to their…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 Shitong Shao , Xiaohan Yuan , Zhen Huang , Ziming Qiu , Shuai Wang , Kevin Zhou

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

Counterfactual explanations and adversarial attacks have a related goal: flipping output labels with minimal perturbations regardless of their characteristics. Yet, adversarial attacks cannot be used directly in a counterfactual explanation…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Guillaume Jeanneret , Loïc Simon , Frédéric Jurie

A ubiquitous challenge in machine learning is the problem of domain generalisation. This can exacerbate bias against groups or labels that are underrepresented in the datasets used for model development. Model bias can lead to unintended…

Precision medicine involves answering counterfactual questions such as "Would this patient respond better to treatment A or treatment B?" These types of questions are causal in nature and require the tools of causal inference to be…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Jacob C. Reinhold , Aaron Carass , Jerry L. Prince

Segmentation of regions of interest (ROIs) for identifying abnormalities is a leading problem in medical imaging. Using machine learning for this problem generally requires manually annotated ground-truth segmentations, demanding extensive…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Jay J. Yoo , Khashayar Namdar , Matthias W. Wagner , Liana Nobre , Uri Tabori , Cynthia Hawkins , Birgit B. Ertl-Wagner , Farzad Khalvati

Accurate identification and localization of abnormalities from radiology images serve as a critical role in computer-aided diagnosis (CAD) systems. Building a highly generalizable system usually requires a large amount of data with…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Euyoung Kim , Soochahn Lee , Kyoung Mu Lee

Generative image models have achieved remarkable progress in both natural and medical imaging. In the medical context, these techniques offer a potential solution to data scarcity-especially for low-prevalence anomalies that impair the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Gregory Schuit , Denis Parra , Cecilia Besa

Exploiting learning algorithms under scarce data regimes is a limitation and a reality of the medical imaging field. In an attempt to mitigate the problem, we propose a data augmentation protocol based on generative adversarial networks. We…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Ahmad B Qasim , Ivan Ezhov , Suprosanna Shit , Oliver Schoppe , Johannes C Paetzold , Anjany Sekuboyina , Florian Kofler , Jana Lipkova , Hongwei Li , Bjoern Menze

Medical image analysis plays a pivotal role in the early diagnosis of diseases such as skin lesions. However, the scarcity of data and the class imbalance significantly hinder the performance of deep learning models. We propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Zhaobin Xu

Medical image segmentation is a challenging task, made more difficult by many datasets' limited size and annotations. Denoising diffusion probabilistic models (DDPM) have recently shown promise in modelling the distribution of natural…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Margherita Rosnati , Melanie Roschewitz , Ben Glocker

Diffusion models have emerged as a popular family of deep generative models (DGMs). In the literature, it has been claimed that one class of diffusion models -- denoising diffusion probabilistic models (DDPMs) -- demonstrate superior image…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Rucha Deshpande , Muzaffer Özbey , Hua Li , Mark A. Anastasio , Frank J. Brooks

In order to take advantage of AI solutions in endoscopy diagnostics, we must overcome the issue of limited annotations. These limitations are caused by the high privacy concerns in the medical field and the requirement of getting aid from…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Roman Macháček , Leila Mozaffari , Zahra Sepasdar , Sravanthi Parasa , Pål Halvorsen , Michael A. Riegler , Vajira Thambawita

Through the use of carefully tailored convolutional neural network architectures, a deep image prior (DIP) can be used to obtain pre-images from latent representation encodings. Though DIP inversion has been known to be superior to…

Machine Learning · Computer Science 2020-10-26 Vivek Narayanaswamy , Jayaraman J. Thiagarajan , Andreas Spanias

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez