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The increased prevalence of observational data and the need to integrate information from multiple sources are critical challenges in contemporary data analysis. Record linkage is a widely used tool for combining datasets in the absence of…

Methodology · Statistics 2025-12-17 Martin Slawski

Although randomized experiments are widely regarded as the gold standard for estimating causal effects, missing data of the pretreatment covariates makes it challenging to estimate the subgroup causal effects. When the missing data…

Statistics Theory · Mathematics 2014-01-08 Peng Ding , Zhi Geng

A central task in the analysis of human movement behavior is to determine systematic patterns and differences across experimental conditions, participants and repetitions. This is possible because human movement is highly regular, being…

Applications · Statistics 2023-01-23 Lars Lau Raket , Britta Grimme , Gregor Schöner , Christian Igel , Bo Markussen

Missing data occur frequently in empirical studies in health and social sciences, often compromising our ability to make accurate inferences. An outcome is said to be missing not at random (MNAR) if, conditional on the observed variables,…

Methodology · Statistics 2019-01-23 BaoLuo Sun , Lan Liu , Wang Miao , Kathleen Wirth , James Robins , Eric Tchetgen Tchetgen

A frequent problem in statistical science is how to properly handle missing data in matched paired observations. There is a large body of literature coping with the univariate case. Yet, the ongoing technological progress in measuring…

Methodology · Statistics 2022-06-06 Marcos Matabuena , Paulo Félix , Marc Ditzhaus , Juan Vidal , Francisco Gude

Although approaches for handling missing data from longitudinal studies are well-developed when the patterns of missingness are monotone, fewer methods are available for non-monotone missingness. Moreover, the conventional missing at random…

Methodology · Statistics 2023-02-28 Boyu Ren , Stuart R. Lipsitz , Roger D. Weiss , Garrett M. Fitzmaurice

Modal regression has emerged as a flexible alternative to classical regression models when the conditional mean or median are unable to adequately capture the underlying relation between a response and a predictor variable. This approach is…

Methodology · Statistics 2025-04-08 Ana Pérez-González , Tomás R. Cotos-Yáñez , Rosa M. Crujeiras

Return-to-baseline is an important method to impute missing values or unobserved potential outcomes when certain hypothetical strategies are used to handle intercurrent events in clinical trials. Current return-to-baseline approaches seen…

Methodology · Statistics 2021-11-19 Yongming Qu , Biyue Dai

Observational studies are the primary source of data for causal inference, but it is challenging when existing unmeasured confounding. Missing data problems are also common in observational studies. How to obtain the causal effects from the…

Methodology · Statistics 2023-05-15 Renzhong Zheng

Attrition in survey and field experiments presents a challenge for social science research. Common approaches to deal with this problem -- such as complete case analysis, multiple imputation, and weighting methods -- rely on strong…

Methodology · Statistics 2026-04-13 Xiangyu Song

Epidemiologic studies and clinical trials with a survival outcome are often challenged by immortal time (IMT), a period of follow-up during which the survival outcome cannot occur because of the observed later treatment initiation. It has…

Applications · Statistics 2022-02-08 Jiping Wang , Peter Peduzzi , Michael Wininger , Shuangge Ma

In longitudinal studies, subjects may be lost to follow-up, or miss some of the planned visits, leading to incomplete response sequences. When the probability of non-response, conditional on the available covariates and the observed…

Methodology · Statistics 2017-07-10 Alessandra Spagnoli , Maria Francesca Marino , Marco Alfò

Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often…

It is often said that the fundamental problem of causal inference is a missing data problem -- the comparison of responses to two hypothetical treatment assignments is made difficult because for every experimental unit only one potential…

Methodology · Statistics 2024-11-21 Razieh Nabi , Rohit Bhattacharya , Ilya Shpitser , James M. Robins

An approach to amputation, the process of introducing missing values to a complete dataset, is presented. It allows to construct missingness indicators in a flexible and principled way via copulas and Bernoulli margins and to incorporate…

Applications · Statistics 2025-07-28 Marius Hofert , James Jackson , Niels Hagenbuch

In the analysis of observational data in social sciences and businesses, it is difficult to obtain a "(quasi) single-source dataset" in which the variables of interest are simultaneously observed. Instead, multiple-source datasets are…

Methodology · Statistics 2021-09-02 Masaki Mitsuhiro , Takahiro Hoshino

Conditions ensuring optimal parameter estimation in the presence of missing data are well established in inference, typically relying on the Missing-at-Random (MAR) assumption. In prediction, similar principles are often assumed to apply.…

Methodology · Statistics 2026-03-19 Pierre Catoire , Robin Genuer , Cecile Proust-Lima

In many applications, researchers seek to identify overlapping entities across multiple data files. Record linkage algorithms facilitate this task, in the absence of unique identifiers. As these algorithms rely on semi-identifying…

Methodology · Statistics 2026-04-24 Gauri Kamat , Roee Gutman

Missing data is pervasive in econometric applications, and rarely is it plausible that the data are missing (completely) at random. This paper proposes a methodology for studying the robustness of results drawn from incomplete datasets.…

Econometrics · Economics 2025-12-29 Daniel Ober-Reynolds

Recent work introduced loss functions which measure the error of a prediction based on multiple simultaneous observations or outcomes. In this paper, we explore the theoretical and practical questions that arise when using such…

Machine Learning · Computer Science 2018-02-28 Rafael Frongillo , Nishant A. Mehta , Tom Morgan , Bo Waggoner