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Anisotropic multi-slice Cardiac Magnetic Resonance (CMR) Images are conventionally acquired in patient-specific short-axis (SAX) orientation. In specific cardiovascular diseases that affect right ventricular (RV) morphology, acquisitions in…

Establishing the reproducibility of radiomic signatures is a critical step in the path to clinical adoption of quantitative imaging biomarkers; however, radiomic signatures must also be meaningfully related to an outcome of clinical…

A regularization algorithm using inexact function values and inexact derivatives is proposed and its evaluation complexity analyzed. This algorithm is applicable to unconstrained problems and to problems with inexpensive constraints (that…

Optimization and Control · Mathematics 2019-04-22 S. Bellavia , G. Gurioli , B. Morini , Ph. L. Toint

The adaptive Metropolis (AM) algorithm of Haario, Saksman and Tamminen [Bernoulli 7 (2001) 223-242] uses the estimated covariance of the target distribution in the proposal distribution. This paper introduces a new robust adaptive…

Computation · Statistics 2011-05-30 Matti Vihola

Intensity modulated radiotherapy (IMRT) is one of the most common modalities for treating cancer patients. One of the biggest challenges is precise treatment delivery that accounts for varying motion patterns originating from…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Matej Gazda , Peter Drotar , Liset Vazquez Romaguera , Samuel Kadoury

Adaptive Radiotherapy (ART) is an emerging technique for treating cancer patients which facilitates higher delivery accuracy and has the potential to reduce toxicity. However, ART is also resource-intensive, requiring extra human and…

Medical Physics · Physics 2022-12-20 Rupesh Ghimire , Kevin L. Moore , Daniela Branco , Dominique L. Rash , Jyoti Mayadev , Xenia Ray

Most current approaches to undersampled multi-coil MRI reconstruction focus on learning the reconstruction model for a fixed, equidistant acquisition trajectory. In this paper, we study the problem of joint learning of the reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Tim Bakker , Matthew Muckley , Adriana Romero-Soriano , Michal Drozdzal , Luis Pineda

Quantitative Susceptibility Mapping (QSM) quantifies tissue magnetic susceptibility from magnetic-resonance phase data and plays a crucial role in brain microstructure imaging, iron-deposition assessment, and neurological-disease research.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-11 Xuan Cai , Ruo-Mi Guo , Xiao-Wen Luo , Jing Zhao , Silun Wang , Tao Tan , Yue Liu , Hongbin Han , Mengting Liu

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

A key feature of magnetic resonance (MR) imaging is its ability to manipulate how the intrinsic tissue parameters of the anatomy ultimately contribute to the contrast properties of the final, acquired image. This flexibility, however, can…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Dzung L. Pham , Snehashis Roy

There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures…

Medical Physics · Physics 2018-03-14 Sean D. Rose , Ingrid Reiser , Emil Y. Sidky , Xiaochuan Pan

This article investigates the integration of quasi-Monte Carlo (QMC) methods using the Adaptive Multiple Importance Sampling (AMIS). Traditional Importance Sampling (IS) often suffers from poor performance since it heavily relies on the…

Numerical Analysis · Mathematics 2025-05-14 Jianlong Chen , Jiarui Du , Xiaoqun Wang , Zhijian He

Background: Phase I dose-finding trials increasingly encounter delayed-onset toxicities, especially with immunotherapies and targeted agents. The time-to-event continual reassessment method (TITE-CRM) handles incomplete follow-up using…

Methodology · Statistics 2026-02-24 Robert Amevor , Emmanuel Kubuafor , Dennis Baidoo

Recent developments in neural networks have improved deformable image registration (DIR) by amortizing iterative optimization, enabling fast and accurate DIR results. However, learning-based methods often face challenges with limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Hang Zhang , Yuxi Zhang , Jiazheng Wang , Xiang Chen , Renjiu Hu , Xin Tian , Gaolei Li , Min Liu

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

In this paper, we propose a new variational model for image reconstruction by minimizing the $L^1$ norm of the \emph{Weingarten map} of image surface $(x,y,f(x,y))$ for a given image $f:{\mathrm{\Omega}}\rightarrow \mathbb R$. We…

Numerical Analysis · Mathematics 2022-04-07 Qiuxiang Zhong , Ryan Wen Liu , Yuping Duan

Real-world data (RWD) gains growing interests to provide a representative sample of the population for selecting the optimal treatment options. However, existing complex black box methods for estimating individualized treatment rules (ITR)…

Methodology · Statistics 2026-01-12 Yunshu Zhang , Shu Yang , Wendy Ye , Ilya Lipkovich , Douglas E. Faries

In resource-constrained environments, one can employ spatial multiplexing cameras to acquire a small number of measurements of a scene, and perform effective reconstruction or high-level inference using purely data-driven neural networks.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Suhas Lohit , Rajhans Singh , Kuldeep Kulkarni , Pavan Turaga

Purpose: This study presents a variable resolution (VR) sampling and deep learning reconstruction approach for multi-spectral MRI near metal implants, aiming to reduce scan times while maintaining image quality. Background: The rising use…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Azadeh Sharafi , Nikolai J. Mickevicius , Mehran Baboli , Andrew S. Nencka , Kevin M. Koch