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Accurate ADMET (an abbreviation for "absorption, distribution, metabolism, excretion, and toxicity") predictions can efficiently screen out undesirable drug candidates in the early stage of drug discovery. In recent years, multiple…

Biomolecules · Quantitative Biology 2022-05-25 Shanzhuo Zhang , Zhiyuan Yan , Yueyang Huang , Lihang Liu , Donglong He , Wei Wang , Xiaomin Fang , Xiaonan Zhang , Fan Wang , Hua Wu , Haifeng Wang

With the emerging trend of GPT models, we have established a framework called AutoML-GPT that integrates a comprehensive set of tools and libraries. This framework grants users access to a wide range of data preprocessing techniques,…

Machine Learning · Computer Science 2023-09-06 Yun-Da Tsai , Yu-Che Tsai , Bo-Wei Huang , Chun-Pai Yang , Shou-De Lin

The increasing demand of dedicated accelerators to improve energy efficiency and performance has highlighted FPGAs as a promising option to deliver both. However, programming FPGAs in hardware description languages requires long time and…

Hardware Architecture · Computer Science 2020-03-31 Maria A. Dávila-Guzmán , Rubén Gran Tejero , María Villarroya-Gaudó , Darío Suárez Gracia

With the insight of variance-bias decomposition, we design a new hybrid bagging-boosting algorithm named SBPMT for classification problems. For the boosting part of SBPMT, we propose a new tree model called Probit Model Tree (PMT) as base…

Machine Learning · Statistics 2023-11-07 Tian Qin , Wei-Min Huang

As large language models (LLMs) become increasingly powerful, the sequential nature of autoregressive generation creates a fundamental throughput bottleneck that limits the practical deployment. While Multi-Token Prediction (MTP) has…

Machine Learning · Computer Science 2025-09-24 Yuxuan Cai , Xiaozhuan Liang , Xinghua Wang , Jin Ma , Haijin Liang , Jinwen Luo , Xinyu Zuo , Lisheng Duan , Yuyang Yin , Xi Chen

Multimodal Large Language Models (MLLMs) are undergoing rapid progress and represent the frontier of AI development. However, their training and inference efficiency have emerged as a core bottleneck in making MLLMs more accessible and…

Transformer-based methods have achieved impressive results in time series forecasting. However, existing Transformers still exhibit limitations in sequence modeling as they tend to overemphasize temporal dependencies. This incurs additional…

Machine Learning · Computer Science 2025-12-16 Tan Wang , Yun Wei Dong , Qi Wang

The focus of this paper is a proof of concept, machine learning (ML) pipeline that extracts heart rate from pressure sensor data acquired on low-power edge devices. The ML pipeline consists an upsampler neural network, a signal quality…

Machine Learning · Computer Science 2022-08-18 Preetam Anbukarasu , Shailesh Nanisetty , Ganesh Tata , Nilanjan Ray

The deployment of large language models (LLMs) presents significant challenges due to their enormous memory footprints, low arithmetic intensity, and stringent latency requirements, particularly during the autoregressive decoding stage.…

Hardware Architecture · Computer Science 2025-11-03 Cenlin Duan , Jianlei Yang , Rubing Yang , Yikun Wang , Yiou Wang , Lingkun Long , Yingjie Qi , Xiaolin He , Ao Zhou , Xueyan Wang , Weisheng Zhao

Machine learning models and libraries can train datasets of different sizes and perform prediction and classification operations, but machine learning models and libraries cause slow and long training times on large datasets. This article…

Machine Learning · Computer Science 2025-09-17 Halil Hüseyin Çalışkan , Talha Koruk

An intrinsic problem of classifiers based on machine learning (ML) methods is that their learning time grows as the size and complexity of the training dataset increases. For this reason, it is important to have efficient computational…

Machine Learning · Computer Science 2013-04-16 Khadoudja Ghanem

This paper presents a hardness-aware deep metric learning (HDML) framework. Most previous deep metric learning methods employ the hard negative mining strategy to alleviate the lack of informative samples for training. However, this mining…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Wenzhao Zheng , Zhaodong Chen , Jiwen Lu , Jie Zhou

Large language models produce powerful text embeddings, but their causal attention mechanism restricts the flow of information from later to earlier tokens, degrading representation quality. While recent methods attempt to solve this by…

Computation and Language · Computer Science 2025-11-20 Xueying Ding , Xingyue Huang , Mingxuan Ju , Liam Collins , Yozen Liu , Leman Akoglu , Neil Shah , Tong Zhao

The acquisition of large-scale and diverse demonstration data are essential for improving robotic imitation learning generalization. However, generating such data for complex manipulations is challenging in real-world settings. We introduce…

Robotics · Computer Science 2025-03-18 Wensheng Wang , Ning Tan

Scientific applications produce vast amounts of data, posing grand challenges in the underlying data management and analytic tasks. Progressive compression is a promising way to address this problem, as it allows for on-demand data…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-02 Yanliang Li , Wenbo Li , Qian Gong , Qing Liu , Norbert Podhorszki , Scott Klasky , Xin Liang , Jieyang Chen

We present High-Throughput Hypothesis Evaluation in Description Logic (HT-HEDL). HT-HEDL is a high-performance hypothesis evaluation engine that accelerates hypothesis evaluation computations for inductive logic programming (ILP) learners…

Artificial Intelligence · Computer Science 2024-12-03 Eyad Algahtani

Transformer-based large language models (LLM) have been widely used in language processing applications. However, due to the memory constraints of the devices, most of them restrict the context window. Even though recurrent models in…

Computation and Language · Computer Science 2025-02-07 Zifan He , Yingqi Cao , Zongyue Qin , Neha Prakriya , Yizhou Sun , Jason Cong

Machine learning techniques lend themselves as promising decision-making and analytic tools in a wide range of applications. Different ML algorithms have various hyper-parameters. In order to tailor an ML model towards a specific…

Machine Learning · Computer Science 2021-09-14 Leila Zahedi , Farid Ghareh Mohammadi , M. Hadi Amini

Symmetric Nonnegative Matrix Factorization (SNMF) models arise naturally as simple reformulations of many standard clustering algorithms including the popular spectral clustering method. Recent work has demonstrated that an elementary…

Computer Vision and Pattern Recognition · Computer Science 2016-09-20 Reza Borhani , Jeremy Watt , Aggelos Katsaggelos

In this paper, an extended combined approach of phrase based statistical machine translation (SMT), example based MT (EBMT) and rule based MT (RBMT) is proposed to develop a novel hybrid data driven MT system capable of outperforming the…

Computation and Language · Computer Science 2017-05-09 Omkar Dhariya , Shrikant Malviya , Uma Shanker Tiwary
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