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We propose the autofocus convolutional layer for semantic segmentation with the objective of enhancing the capabilities of neural networks for multi-scale processing. Autofocus layers adaptively change the size of the effective receptive…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Yao Qin , Konstantinos Kamnitsas , Siddharth Ancha , Jay Nanavati , Garrison Cottrell , Antonio Criminisi , Aditya Nori

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Self-supervised learning (SSL) has emerged as a powerful strategy for representation learning under limited annotation regimes, yet its effectiveness remains highly sensitive to many factors, especially the nature of the target task. In…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jorge Quesada , Ghassan AlRegib

This paper proposes a novel deep subspace clustering approach which uses convolutional autoencoders to transform input images into new representations lying on a union of linear subspaces. The first contribution of our work is to insert…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Mohsen Kheirandishfard , Fariba Zohrizadeh , Farhad Kamangar

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

Self-supervised learning aims to learn representations from the data itself without explicit manual supervision. Existing efforts ignore a crucial aspect of self-supervised learning - the ability to scale to large amount of data because…

Computer Vision and Pattern Recognition · Computer Science 2019-06-07 Priya Goyal , Dhruv Mahajan , Abhinav Gupta , Ishan Misra

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

In visual recognition tasks, such as image classification, unsupervised learning exploits cheap unlabeled data and can help to solve these tasks more efficiently. We show that the recursive autoconvolution operator, adopted from physics,…

Computer Vision and Pattern Recognition · Computer Science 2017-03-28 Boris Knyazev , Erhardt Barth , Thomas Martinetz

Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Zhenqi He , Mathias Unberath , Jing Ke , Yiqing Shen

While scale-invariant modeling has substantially boosted the performance of visual recognition tasks, it remains largely under-explored in deep networks based image restoration. Naively applying those scale-invariant techniques (e.g.…

Computer Vision and Pattern Recognition · Computer Science 2019-12-20 Yuchen Fan , Jiahui Yu , Ding Liu , Thomas S. Huang

Encoder transformer models compress information from all tokens in a sequence into a single [CLS] token to represent global context. This approach risks diluting fine-grained or hierarchical features, leading to information loss in…

Computation and Language · Computer Science 2025-09-23 Asif Shahriar , Rifat Shahriyar , M Saifur Rahman

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Scaling up self-supervised learning has driven breakthroughs in language and vision, yet comparable progress has remained elusive in reinforcement learning (RL). In this paper, we study building blocks for self-supervised RL that unlock…

Machine Learning · Computer Science 2026-02-03 Kevin Wang , Ishaan Javali , Michał Bortkiewicz , Tomasz Trzciński , Benjamin Eysenbach

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

We present a scalable approach for semi-supervised learning on graph-structured data that is based on an efficient variant of convolutional neural networks which operate directly on graphs. We motivate the choice of our convolutional…

Machine Learning · Computer Science 2017-02-23 Thomas N. Kipf , Max Welling

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

In this work we establish the relation between optimal control and training deep Convolution Neural Networks (CNNs). We show that the forward propagation in CNNs can be interpreted as a time-dependent nonlinear differential equation and…

Neural and Evolutionary Computing · Computer Science 2017-06-23 Eldad Haber , Lars Ruthotto , Elliot Holtham , Seong-Hwan Jun
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