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Proliferation of uninfected as well as infected hepatocytes and recycling of DNA-containing capsids are two major mechanisms playing significant roles in the clearance of hepatitis B virus (HBV) infection. In this study, the temporal…

Populations and Evolution · Quantitative Biology 2024-01-23 Rupchand Sutradhar , D C Dalal

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

The growth of several biological tissues is known to be controlled in part by local geometrical features, such as the curvature of the tissue interface. This control leads to changes in tissue shape that in turn can affect the tissue's…

Tissues and Organs · Quantitative Biology 2016-12-01 Almie Alias , Pascal R Buenzli

Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces,…

Soft Condensed Matter · Physics 2025-07-08 Edwina F. Yeo , Benjamin J. Walker , Philip Pearce , Mohit P. Dalwadi

We consider a one-dimensional elastic membrane, which is pushed by growing filaments. The filaments tend to grow by creating local protrusions in the membrane and this process has surface energy and bending energy costs. Although it is…

Biological Physics · Physics 2019-08-05 Raj Kumar Sadhu , Sakuntala Chatterjee

For dry foams, the transport of gas from small high-pressure bubbles to large low-pressure bubbles is dominated by diffusion across the thin soap films separating neighboring bubbles. For wetter foams, the film areas become smaller as the…

Soft Condensed Matter · Physics 2017-10-04 C. D. Schimming , D. J. Durian

Respiration in bacteria involves a sequence of energetically-coupled electron and proton transfers creating an electrochemical gradient of protons (a proton-motive force) across the inner bacterial membrane. With a simple kinetic model we…

Biological Physics · Physics 2015-05-13 Anatoly Yu. Smirnov , Sergey E. Savel'ev , Franco Nori

A biofilm is a microbial city. It consists of bacteria embedded in an extracellular polymeric substance (EPS) that functions as a protective barrier. Quorum sensing (QS) is a method of bacterial communication, where autoinducers (AIs)…

Signal Processing · Electrical Eng. & Systems 2024-08-15 Yanahan Paramalingam , Hamidreza Arjmandi , Freya Harrison , Tara Schiller , Adam Noel

Cell cortex contraction is essential for shaping cells, enabling movement, ensuring proper division, maintaining tissue integrity, guiding development, and responding to mechanical signals - all critical for the life and health of…

Biological Physics · Physics 2024-09-05 Emanuel F. Teixeira , Carine P. Beatrici , Heitor C. M. Fernandes , Leonardo G. Brunnet

Cell polarization underlies many cellular processes, such as differentiation, migration, and budding. Many living cells, such as budding yeast and fission yeast, use cytoskeletal structures to actively transport proteins to one location on…

Biological Physics · Physics 2022-06-22 Harmen Wierenga , Pieter Rein ten Wolde

Droplet patterns condensing on solid substrates (breath figures) tend to evolve into a self-similar regime, characterized by a bimodal droplet size distribution. The distributions comprise a bell-shaped peak of monodisperse large droplets,…

Fluid Dynamics · Physics 2015-10-28 L. Stricker , J. Vollmer

The membrane tubulation induced by banana-shaped protein rods is investigated by using coarse-grained meshless membrane simulations. It is found that the tubulation is promoted by laterally isotropic membrane inclusions that generate the…

Soft Condensed Matter · Physics 2017-10-10 Hiroshi Noguchi

The cell membrane deforms during endocytosis to surround extracellular material and draw it into the cell. Experiments on endocytosis in yeast all agree that (i) actin polymerizes into a network of filaments exerting active forces on the…

Cell Behavior · Quantitative Biology 2015-04-07 T. Zhang , R. Sknepnek , M. J. Bowick , J. M. Schwarz

Bacteriophages infect cells by attaching to the outer membrane and injecting their DNA into the cell.The phage DNA is then transcribed by the cell's transcription machinery.A number of physical mechanisms by which DNA can be translocated…

Biological Physics · Physics 2013-01-10 Sandip Ghosal

Cell adhesion proteins are transmembrane proteins that bind cells to their environment. These proteins typically cluster into disk-shaped or linear structures. Here we show that such clustering patterns spontaneously emerge when the protein…

Soft Condensed Matter · Physics 2023-07-10 Shao-Zhen Lin , Rishita Changede , Michael P. Sheetz , Jacques Prost , Jean-Francois Rupprecht

Multipartite viruses replicate through a puzzling evolutionary strategy. Their genome is segmented into two or more parts, and encapsidated in separate particles that appear to propagate independently. Completing the replication cycle,…

Physics and Society · Physics 2019-03-26 Eugenio Valdano , Susanna Manrubia , Sergio Gómez , Alex Arenas

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

Budding-cell packings jam before all buds are mechanically constrained. The post-jamming state is therefore set by both the pressure $P$ and the fraction $u$ of buds that remain unconstrained. We develop a mean-field theory for this regime.…

Soft Condensed Matter · Physics 2026-05-26 Pawel Gniewek

The optimal shapes attained by contractile cells on adhesive substrates are determined by the interplay between intracellular forces and adhesion with the extracellular matrix. We model the cell as a contractile film bounded by an elastic…

Biological Physics · Physics 2013-05-10 Shiladitya Banerjee , Luca Giomi

Diffusion barriers for a cluster of three water molecules on Pd(111) have been estimated from ab-initio Density Functional Theory. A model for the diffusion of the trimer based in rotations yields a simple explanation of why the cluster can…

Materials Science · Physics 2016-04-04 Victor A. Ranea , P. L. de Andres
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