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Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

Now that disease-modifying therapies for Alzheimer disease have been approved by regulatory agencies, the early, objective, and accurate clinical diagnosis of AD based on the lowest-cost measurement modalities possible has become an…

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression…

Neural networks and deep learning are changing the way that artificial intelligence is being done. Efficiently choosing a suitable network architecture and fine-tune its hyper-parameters for a specific dataset is a time-consuming task given…

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…

Graph neural networks have emerged as a promising approach for the analysis of non-Euclidean data such as meshes. In medical imaging, mesh-like data plays an important role for modelling anatomical structures, and shape classification can…

Alzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specificity. This study aims to detect significant…

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Alzheimer's disease is a major cause of dementia. Its diagnosis requires accurate biomarkers that are sensitive to disease stages. In this respect, we regard probabilistic classification as a method of designing a probabilistic biomarker…

Alzheimer's disease (AD) is the most common form of dementia, which causes problems with memory, thinking and behavior. Growing evidence has shown that the brain connectivity network experiences alterations for such a complex disease.…

In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…

Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

Genome-wide association studies (GWAS) have achieved great success in the genetic study of Alzheimer's disease (AD). Collaborative imaging genetics studies across different research institutions show the effectiveness of detecting genetic…

Alzheimer's disease is a debilitating disorder marked by a decline in cognitive function. Timely identification of the disease is essential for the development of personalized treatment strategies that aim to mitigate its progression. The…

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…