English
Related papers

Related papers: RNA foldings and Stuck Knots

200 papers

In his 1957 paper, John Milnor introduced a collection of invariants for links in $S^3$ detecting higher-order linking phenomena by studying lower central quotients of link groups and comparing them to those of the unlink. These invariants,…

Geometric Topology · Mathematics 2026-05-06 Ryan Stees

RNA co-transcriptional folding has long been suspected to play an active role in helping proper native folding of ribozymes and structured regulatory motifs in mRNA untranslated regions. Yet, the underlying mechanisms and coding…

Biomolecules · Quantitative Biology 2007-05-23 A. Xayaphoummine , V. Viasnoff , S. Harlepp , H. Isambert

We introduce and study knotoids. Knotoids are represented by diagrams in a surface which differ from the usual knot diagrams in that the underlying curve is a segment rather than a circle. Knotoid diagrams are considered up to Reidemeister…

Geometric Topology · Mathematics 2011-04-14 Vladimir Turaev

We present a novel topological classification of RNA secondary structures with pseudoknots. It is based on the topological genus of the circular diagram associated to the RNA base-pair structure. The genus is a positive integer number,…

Biomolecules · Quantitative Biology 2007-05-23 Michael Bon , Graziano Vernizzi , Henri Orland , A. Zee

The presence of slipknots in configurations of proteins and DNA has been shown to affect their functionality, or alter it entirely. Historically, polymers are modeled as polygonal chains in space. As an alternative to space curves, we…

Geometric Topology · Mathematics 2018-03-21 Harrison Chapman

Simple closed curves in the plane can be mapped to nontrivial knots under the action of origami foldings that allow the paper to self-intersect. We show all tame knot types may be produced in this manner, motivating the development of a new…

Geometric Topology · Mathematics 2021-05-05 Joseph Slote , Thomas Bertschinger

This paper is a survey of knot theory and invariants of knots and links from the point of view of categories of diagrams. The topics range from foundations of knot theory to virtual knot theory and topological quantum field theory.

General Topology · Mathematics 2007-05-23 Louis H. Kauffman

This paper explores the problem of unknotting closed braids and classical knots in mathematical knot theory. We apply evolutionary computation methods to learn sequences of moves that simplify knot diagrams, and show that this can be…

Geometric Topology · Mathematics 2013-02-05 Nicholas Jackson , Colin G. Johnson

The aim of this paper is to define a homology theory for racks with finite rank N and use it to define invariants of knots generalizing the CJKLS 2-cocycle invariants related to the invariants defined in [15]. For this purpose, we prove…

Geometric Topology · Mathematics 2011-05-24 Mohamed Elhamdadi , Sam Nelson

In this article we discuss applications of neural networks to recognising knots and, in particular, to the unknotting problem. One of motivations for this study is to understand how neural networks work on the example of a problem for which…

Geometric Topology · Mathematics 2022-11-28 L. H. Kauffman , N. E. Russkikh , I. A. Taimanov

The folding of RNA and DNA strands plays crucial roles in biological systems and bionanotechnology. However, studying these processes with high-resolution numerical models is beyond current computational capabilities due to the timescales…

Soft Condensed Matter · Physics 2024-02-07 F. Tosti Guerra , E. Poppleton , P. Šulc , L. Rovigatti

We examine the conformations of a model for a short segment of closed DNA. The molecule is represented as a cylindrically symmetric elastic rod with a constraint corresponding to a specification of the linking number. We obtain analytic…

Soft Condensed Matter · Physics 2009-10-31 Boris Fain , Joseph Rudnick

Recent single-molecule pulling experiments have shown how it is possible to manipulate RNA molecules using optical tweezers force microscopy. We investigate a minimal model for the experimental setup which includes a RNA molecule connected…

Statistical Mechanics · Physics 2009-11-10 Maria Manosas , Felix Ritort

In this paper, we construct invariants of braids, knots and links by studying dynamics of points in $\R^{2}$ and applying the Ptolemy relation $ac+bd=xy$.

Geometric Topology · Mathematics 2019-01-23 Vassily Olegovich Manturov

This is a survey article about the connections between knot theory and four-dimensional topology. Every four-manifold can be represented in terms of a link, by a Kirby diagram. This point of view has led to progress in computing invariants…

Geometric Topology · Mathematics 2026-03-31 Ciprian Manolescu

The central discovery of $2d$ conformal theory was holomorphic factorization, which expressed correlation functions through bilinear combinations of conformal blocks, which are easily cut and joined without a need to sum over the entire…

High Energy Physics - Theory · Physics 2018-10-02 A. Mironov , A. Morozov , An. Morozov

Knot theory is a study of the embedding of closed circles into three-dimensional Euclidean space, motivated the ubiquity of knots in daily life and human civilization. However, the current knot theory focuses on the topology rather than…

Geometric Topology · Mathematics 2024-11-19 Li Shen , Jian Liu , Guo-Wei Wei

Grid diagrams with their relatively simple mathematical formalism provide a convenient way to generate and model projections of various knots. It has been an open question whether these 2D diagrams can be used to model a complex 3D process…

Biomolecules · Quantitative Biology 2019-09-16 Agnese Barbensi , Daniele Celoria , Heather A. Harrington , Andrzej Stasiak , Dorothy Buck

Using force as a probe to map the folding landscapes of RNA molecules has become a reality thanks to major advances in single molecule pulling experiments. Although the unfolding pathways under tension are complicated to predict studies in…

Biological Physics · Physics 2018-03-14 Changbong Hyeon , D. Thirumalai

Dual graphs have been applied to model RNA secondary structures with pseudoknots, or intertwined base pairs. In previous works, a linear-time algorithm was introduced to partition dual graphs into maximally connected components called…

Biomolecules · Quantitative Biology 2021-09-09 Louis Petingi