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Transcription factors regulate gene expression, but how these proteins recognize and specifically bind to their DNA targets is still debated. Machine learning models are effective means to reveal interaction mechanisms. Here we studied the…

Quantum Physics · Physics 2018-03-02 Richard Y. Li , Rosa Di Felice , Remo Rohs , Daniel A. Lidar

Quantum annealing is a generic algorithm using quantum-mechanical fluctuations to search for the solution of an optimization problem. The present paper first reviews the fundamentals of quantum annealing and then reports on preliminary…

Disordered Systems and Neural Networks · Physics 2010-06-10 Masayuki Ohzeki , Hidetoshi Nishimori

The worldline approach to Quantum Field Theory (QFT) allows to efficiently compute several quantities, such as one-loop effective actions, scattering amplitudes and anomalies, which are linked to particle path integrals on the circle. A…

High Energy Physics - Theory · Physics 2018-11-07 Olindo Corradini , Maurizio Muratori

We study the Schr\"odinger equation in quantum field theory (QFT) in its functional formulation. In this approach quantum correlation functions can be expressed as classical expectation values over (complex) stochastic processes. We obtain…

High Energy Physics - Theory · Physics 2024-04-19 Z. Haba

By extending the method developed in our recent paper \cite{LM} we present the AQFT framework in terms of von Neumann algebras. In particular, this approach allows for a locally covariant categorical description of AQFT which moreover…

Mathematical Physics · Physics 2026-01-28 Louis E Labuschagne , W Adam Majewski

Quantum annealing leverages the properties of interacting quantum spin systems to solve computational problems, typically optimisation problems. Current hardware now has capabilities that can be used to solve condensed matter physics…

Quantum Physics · Physics 2026-04-09 Viv Kendon , Nicholas Chancellor

Quantum annealing is typically regarded as a tool for combinatorial optimization, but its coherent dynamics also offer potential for machine learning. We present a model that encodes classical data into an Ising Hamiltonian, evolves it on a…

Quantum annealing is a promising approach to heuristically solving difficult combinatorial optimization problems. However, the connectivity limitations in current devices lead to an exponential degradation of performance on general…

Quantum Physics · Physics 2020-10-06 Tatsuhiro Onodera , Edwin Ng , Peter L. McMahon

Scaling full finetuning of large foundation models strains GPU memory and training time. Parameter Efficient Fine-Tuning (PEFT) methods address this issue via adapter modules which update only a small subset of model parameters. In this…

Machine Learning · Computer Science 2025-10-07 Snehal Raj , Brian Coyle

We address estimation of the minimum length arising from gravitational theories. In particular, we provide bounds on precision and assess the use of quantum probes to enhance the estimation performances. At first, we review the concept of…

Quantum Physics · Physics 2020-09-16 Alessandro Candeloro , Cristian Degli Esposti Boschi , Matteo G. A. Paris

In this work we report on a new bootstrap method for quantum mechanical problems that closely mirrors the setup from conformal field theory (CFT). We use the equations of motion to develop an analogue of the conformal block expansion for…

High Energy Physics - Theory · Physics 2023-04-26 Colin Oscar Nancarrow , Yuan Xin

Finding shape correspondences can be formulated as an NP-hard quadratic assignment problem (QAP) that becomes infeasible for shapes with high sampling density. A promising research direction is to tackle such quadratic optimization problems…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Marcel Seelbach Benkner , Zorah Lähner , Vladislav Golyanik , Christof Wunderlich , Christian Theobalt , Michael Moeller

We propose a novel method for reducing the number of variables in quadratic unconstrained binary optimization problems, using a quantum annealer (or any sampler) to fix the value of a large portion of the variables to values that have a…

Quantum Physics · Physics 2017-09-26 Hamed Karimi , Gili Rosenberg

We apply digitized Quantum Annealing (QA) and Quantum Approximate Optimization Algorithm (QAOA) to a paradigmatic task of supervised learning in artificial neural networks: the optimization of synaptic weights for the binary perceptron. At…

Quantum Physics · Physics 2021-12-21 Pietro Torta , Glen B. Mbeng , Carlo Baldassi , Riccardo Zecchina , Giuseppe E. Santoro

This study presents a generalised least squares based method for fitting polygons and ellipses to data points. The method is based on a trigonometric fitness function that approximates a unit shape accurately, making it applicable to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Yiming Quan , Shian Chen

Quantum annealing can efficiently obtain solutions to combinatorial optimization problems. Size-reduction methods are used to treat large-scale combinatorial optimization problems that cannot be input directly into a quantum annealer…

Statistical Mechanics · Physics 2024-12-30 Tomohiro Hattori , Hirotaka Irie , Tadashi Kadowaki , Shu Tanaka

One of the key applications for quantum computers will be the simulation of other quantum systems that arise in chemistry, materials science, etc, in order to accelerate the process of discovery. It is important to ask: Can this be achieved…

Quantum Physics · Physics 2017-07-05 Ying Li , Simon C. Benjamin

Small clusters of $^4$He atoms provide a paradigmatic setting for exploring universal phenomena in few-body quantum systems with large scattering length. Their weakly bound states serve as ideal test cases for studying Efimov physics and…

Quantum Gases · Physics 2025-11-18 Betzalel Bazak

We present a novel methodology for automated feature subset selection from a pool of physiological signals using Quantum Annealing (QA). As a case study, we will investigate the effectiveness of QA-based feature selection techniques in…

Quantum Physics · Physics 2021-06-10 Rajdeep Kumar Nath , Himanshu Thapliyal , Travis S. Humble

Quantum computers have the potential to solve some important industrial and scientific problems with greater efficiency than classical computers. While most current realizations focus on two-level qubits, the underlying physics used in most…

Quantum Physics · Physics 2023-01-06 Kevin Mato , Martin Ringbauer , Stefan Hillmich , Robert Wille
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