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Fitting spatio-temporal models for areal data is crucial in many fields such as cancer epidemiology. However, when data sets are very large, many issues arise. The main objective of this paper is to propose a general procedure to analyze…

Methodology · Statistics 2023-02-06 E. Orozco-Acosta , A. Adin , M. D. Ugarte

This paper illustrates the main results of a spatio-temporal interpolation process of $\text{PM}_{10}$ concentrations at daily resolution using a set of 410 monitoring sites, distributed throughout the Italian territory, for the year 2015.…

Applications · Statistics 2021-02-24 Guido Fioravanti , Sara Martino , Michela Cameletti , Giorgio Cattani

Bayesian hierarchical models with latent Gaussian layers have proven very flexible in capturing complex stochastic behavior and hierarchical structures in high-dimensional spatial and spatio-temporal data. Whereas simulation-based Bayesian…

Methodology · Statistics 2017-08-10 Thomas Opitz

Studies of the relationships between environmental exposures and adverse health outcomes often rely on a two-stage statistical modeling approach, where exposure is modeled/predicted in the first stage and used as input to a separately fit…

Methodology · Statistics 2022-04-01 Saskia Comess , Howard H. Chang , Joshua L. Warren

High dimensional space-time data pose known computational challenges when fitting spatio-temporal models. Such data show dependence across several dimensions of space as well as in time, and can easily involve hundreds of thousands of…

Methodology · Statistics 2025-06-02 Staci Hepler , Rob Erhardt

The Integrated Nested Laplace Approximation (INLA) is a deterministic approach to Bayesian inference on latent Gaussian models (LGMs) and focuses on fast and accurate approximation of posterior marginals for the parameters in the models.…

Computation · Statistics 2021-03-05 Martin Outzen Berild , Sara Martino , Virgilio Gómez-Rubio , Håvard Rue

Spatial misalignment arises when datasets are aggregated or collected at different spatial scales, leading to information loss. We develop a Bayesian disaggregation framework that links misaligned data to a continuous-domain model through…

Methodology · Statistics 2025-12-16 Man Ho Suen , Mark Naylor , Finn Lindgren

Spatio-temporal prediction of levels of an environmental exposure is an important problem in environmental epidemiology. Our work is motivated by multiple studies on the spatio-temporal distribution of mobile source, or traffic related,…

Applications · Statistics 2014-11-14 Nikolay Bliznyuk , Christopher J. Paciorek , Joel Schwartz , Brent Coull

Causal inference in spatial domains faces two intertwined challenges: (1) unmeasured spatial factors, such as weather, air pollution, or mobility, that confound treatment and outcome, and (2) interference from nearby treatments that violate…

Machine Learning · Computer Science 2025-10-13 Ayush Khot , Miruna Oprescu , Maresa Schröder , Ai Kagawa , Xihaier Luo

Public health researchers often estimate health effects of exposures (e.g., pollution, diet, lifestyle) that cannot be directly measured for study subjects. A common strategy in environmental epidemiology is to use a first-stage (exposure)…

Methodology · Statistics 2014-06-03 Adam A. Szpiro , Christopher J. Paciorek

In the first stage of a two-stage study, the researcher uses a statistical model to impute the unobserved exposures. In the second stage, imputed exposures serve as covariates in epidemiological models. Imputation error in the first stage…

Applications · Statistics 2021-07-19 Ron Sarafian , Itai Kloog , Jonathan D. Rosenblatt

State-space models are used to describe and analyse dynamical systems. They are ubiquitously used in many scientific fields such as signal processing, finance and ecology to name a few. Particle filters are popular inferential methods used…

Computation · Statistics 2024-12-20 Alaa Amri

We address in this paper a new approach for fitting spatiotemporal models with application in disease mapping using the interaction types 1,2,3, and 4. When we account for the spatiotemporal interactions in disease-mapping models, inference…

Methodology · Statistics 2022-06-22 Esmail Abdul Fattah , Haavard Rue

Data fusion models are widely used in air quality monitoring to integrate in situ and large-scale gridded products, offering spatially complete and temporally detailed estimates. However, traditional Gaussian-based models often…

Applications · Statistics 2026-05-18 M. Daniela Cuba , Craig Wilkie , Marian Scott , Daniela Castro-Camilo

Despite the amount of research on disease mapping in recent years, the use of multivariate models for areal spatial data remains limited due to difficulties in implementation and computational burden. These problems are exacerbated when the…

Methodology · Statistics 2023-07-24 G. Vicente , A. Adin , T. Goicoa , M. D. Ugarte

Laplacian-P-splines (LPS) associate the P-splines smoother and the Laplace approximation in a unifying framework for fast and flexible inference under the Bayesian paradigm. Gaussian Markov field priors imposed on penalized latent variables…

Methodology · Statistics 2023-09-18 Philippe Lambert , Oswaldo Gressani

This paper proposes a novel low-rank approximation to the multivariate State-Space Model. The Stochastic Partial Differential Equation (SPDE) approach is applied component-wise to the independent-in-time Mat\'ern Gaussian innovation term in…

Accounting for exposure measurement errors has been recognized as a crucial problem in environmental epidemiology for over two decades. Bayesian hierarchical models offer a coherent probabilistic framework for evaluating associations…

Methodology · Statistics 2024-01-17 Changwoo J. Lee , Elaine Symanski , Amal Rammah , Dong Hun Kang , Philip K. Hopke , Eun Sug Park

We present a novel Bayesian spatial disaggregation model for count data, providing fast and flexible inference at high resolution. First, it incorporates non-linear covariate effects using penalized splines, a flexible approach that is not…

Methodology · Statistics 2026-04-13 Sara Rutten , Thomas Neyens , Elisa Duarte , Christel Faes

Collecting multiple longitudinal measurements and time-to-event outcomes is a common practice in clinical and epidemiological studies, often focusing on exploring associations between them. Joint modeling is the standard analytical tool for…

Methodology · Statistics 2024-12-10 Taban Baghfalaki , Reza Hashemi , Catherine Helmer , Helene Jacqmin-Gadda