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This paper proposes and analyzes a new method for quantum state estimation, called hedged maximum likelihood (HMLE). HMLE is a quantum version of Lidstone's Law, also known as the "add beta" rule. A straightforward modification of maximum…

Quantum Physics · Physics 2010-11-11 Robin Blume-Kohout

Misclassified variables used in regression models, either as a covariate or as the response, may lead to biased estimators and incorrect inference. Even though Bayesian models to adjust for misclassification error exist, it has not been…

Methodology · Statistics 2024-11-26 Emma Skarstein , Leonardo Soares Bastos , Håvard Rue , Stefanie Muff

We address the challenge of performing Targeted Maximum Likelihood Estimation (TMLE) after an initial Highly Adaptive Lasso (HAL) fit. Existing approaches that utilize the data-adaptive working model selected by HAL-such as the relaxed HAL…

Methodology · Statistics 2025-06-23 Yi Li , Sky Qiu , Zeyi Wang , Mark van der Laan

Variational approaches to approximate Bayesian inference provide very efficient means of performing parameter estimation and model selection. Among these, so-called variational-Laplace or VL schemes rely on Gaussian approximations to…

Methodology · Statistics 2018-01-17 Jean Daunizeau

We consider Bayesian variable selection in sparse high-dimensional regression, where the number of covariates $p$ may be large relative to the samples size $n$, but at most a moderate number $q$ of covariates are active. Specifically, we…

Statistics Theory · Mathematics 2015-03-31 Rina Foygel Barber , Mathias Drton , Kean Ming Tan

Accurately estimating high quantiles beyond the largest observed value is crucial for risk assessment and devising effective adaptation strategies to prevent a greater disaster. The generalized extreme value distribution is widely used for…

Methodology · Statistics 2026-02-24 Yonggwan Shin , Yire Shin , Jeong-Soo Park

Using a hierarchical construction, we develop methods for a wide and flexible class of models by taking a fully parametric approach to generalized linear mixed models with complex covariance dependence. The Laplace approximation is used to…

Methodology · Statistics 2024-07-31 Jay M. Ver Hoef , Eryn Blagg , Michael Dumelle , Philip M. Dixon , Dale L. Zimmerman , Paul Conn

The Laplace approximation has been one of the workhorses of Bayesian inference. It often delivers good approximations in practice despite the fact that it does not strictly take into account where the volume of posterior density lies.…

Machine Learning · Statistics 2022-03-02 Nikolaos Gianniotis

We study mixture of linear regression (random coefficient) models, which capture population heterogeneity by allowing the regression coefficients to follow an unknown distribution $G^*$. In contrast to common parametric methods that fix the…

Methodology · Statistics 2025-07-01 Hansheng Jiang , Adityanand Guntuboyina

The Integrated Nested Laplace Approximation (INLA) is a deterministic approach to Bayesian inference on latent Gaussian models (LGMs) and focuses on fast and accurate approximation of posterior marginals for the parameters in the models.…

Computation · Statistics 2021-03-05 Martin Outzen Berild , Sara Martino , Virgilio Gómez-Rubio , Håvard Rue

In applications of Bayesian procedures, once a class of priors has been chosen, it may be tempting to fix the prior's hyperparameters from the data, in an empirical Bayes (EB) fashion, usually by their maximum marginal likelihood estimates…

Statistics Theory · Mathematics 2026-04-14 Stefano Rizzelli , Judith Rousseau , Sonia Petrone

This paper develops a unified estimation framework, the Maximum Ideal Likelihood Estimation (MILE), for general parametric models with latent variables. Unlike traditional approaches relying on the marginal likelihood of the observed data,…

Statistics Theory · Mathematics 2025-10-08 Yizhou Cai , Ting Fung Ma

In this paper we study the computation of the nonparametric maximum likelihood estimator (NPMLE) in multivariate mixture models. Our first approach discretizes this infinite dimensional convex optimization problem by fixing the support…

Methodology · Statistics 2024-02-20 Yangjing Zhang , Ying Cui , Bodhisattva Sen , Kim-Chuan Toh

To account for measurement error (ME) in explanatory variables, Bayesian approaches provide a flexible framework, as expert knowledge about unobserved covariates can be incorporated in the prior distributions. However, given the analytic…

Methodology · Statistics 2013-08-19 Stefanie Muff , Andrea Riebler , Havard Rue , Philippe Saner , Leonhard Held

Linear birth-and-death processes (LBDPs) are foundational stochastic models in population dynamics, evolutionary biology, and hematopoiesis. Estimating parameters from discretely observed data is computationally demanding due to irregular…

Computation · Statistics 2025-08-26 Xiaochen Long , Marek Kimmel

Mixtures-of-Experts models and their maximum likelihood estimation (MLE) via the EM algorithm have been thoroughly studied in the statistics and machine learning literature. They are subject of a growing investigation in the context of…

Machine Learning · Statistics 2019-09-13 Faïcel Chamroukhi , Florian Lecocq , Hien D. Nguyen

Integrated Nested Laplace Approximations (INLA) has been a successful approximate Bayesian inference framework since its proposal by Rue et al. (2009). The increased computational efficiency and accuracy when compared with sampling-based…

Methodology · Statistics 2025-10-02 Janet van Niekerk , Elias Krainski , Denis Rustand , Haavard Rue

The linearized-Laplace approximation (LLA) has been shown to be effective and efficient in constructing Bayesian neural networks. It is theoretically compelling since it can be seen as a Gaussian process posterior with the mean function…

Machine Learning · Computer Science 2023-07-13 Agustinus Kristiadi , Alexander Immer , Runa Eschenhagen , Vincent Fortuin

Many models require integrals of high-dimensional functions: for instance, to obtain marginal likelihoods. Such integrals may be intractable, or too expensive to compute numerically. Instead, we can use the Laplace approximation (LA). The…

Methodology · Statistics 2024-11-05 Shaun McDonald , David Campbell

Approximate Bayesian inference typically revolves around computing the posterior parameter distribution. In practice, however, the main object of interest is often a model's predictions rather than its parameters. In this work, we propose…

Machine Learning · Statistics 2026-05-29 Julian Rodemann , Alexander Marquard , Thomas Augustin , Michele Caprio