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Deep learning has achieved unprecedented success in various object detection tasks with huge amounts of labeled data. However, obtaining large-scale annotations for medical images is extremely challenging due to the high demand of labour…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Zhizhong Chai , Luyang Luo , Huangjing Lin , Hao Chen , Anjia Han , Pheng-Ann Heng

Accurate and efficient cell detection is crucial in many biomedical image analysis tasks. We evaluate the performance of several Deep Learning (DL) methods for cell detection in Papanicolaou-stained cytological Whole Slide Images (WSIs),…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Marco Acerbis , Nataša Sladoje , Joakim Lindblad

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

Deep learning based image segmentation has achieved the state-of-the-art performance in many medical applications such as lesion quantification, organ detection, etc. However, most of the methods rely on supervised learning, which require a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-20 Ruizhe Li , Dorothee Auer , Christian Wagner , Xin Chen

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Deep convolutional neural networks (DCNNs) trained on a large number of images with strong pixel-level annotations have recently significantly pushed the state-of-art in semantic image segmentation. We study the more challenging problem of…

Computer Vision and Pattern Recognition · Computer Science 2015-10-07 George Papandreou , Liang-Chieh Chen , Kevin Murphy , Alan L. Yuille

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Phase contrast transmission electron microscopy (TEM) is a powerful tool for imaging the local atomic structure of materials. TEM has been used heavily in studies of defect structures of 2D materials such as monolayer graphene due to its…

Materials Science · Physics 2021-09-01 Robbie Sadre , Colin Ophus , Anstasiia Butko , Gunther H Weber

Finding an optimal correspondence between point sets is a common task in computer vision. Existing techniques assume relatively simple relationships among points and do not guarantee an optimal match. We introduce an algorithm capable of…

Computer Vision and Pattern Recognition · Computer Science 2023-01-11 Andrew Lauziere , Ryan Christensen , Hari Shroff , Radu Balan

Deep learning architectures are showing great promise in various computer vision domains including image classification, object detection, event detection and action recognition. In this study, we investigate various aspects of…

Computer Vision and Pattern Recognition · Computer Science 2016-08-08 Hilal Ergun , Mustafa Sert

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

We present an automated method to track and identify neurons in C. elegans, called "fast Deep Learning Correspondence" or fDLC, based on the transformer network architecture. The model is trained once on empirically derived synthetic data…

Quantitative Methods · Quantitative Biology 2021-07-16 Xinwei Yu , Matthew S. Creamer , Francesco Randi , Anuj K. Sharma , Scott W. Linderman , Andrew M. Leifer

We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Recent advances in deep learning, like 3D fully convolutional networks (FCNs), have improved the state-of-the-art in dense semantic segmentation of medical images. However, most network architectures require severely downsampling or…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Holger R. Roth , Chen Shen , Hirohisa Oda , Takaaki Sugino , Masahiro Oda , Yuichiro Hayashi , Kazunari Misawa , Kensaku Mori

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori