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We consider the problem of estimating an unbiased and reference-free ab-inito model for non-symmetric molecules from images generated by single-particle cryo-electron microscopy. The proposed algorithm finds the globally optimal assignment…

Quantitative Methods · Quantitative Biology 2018-10-30 Ido Greenberg , Yoel Shkolnisky

Speech classification has attracted increasing attention due to its wide applications, particularly in classifying physical and mental states. However, these tasks are challenging due to the high variability in speech signals. Ensemble…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-25 Bagus Tris Atmaja , Felix Burkhardt

Network clustering reveals the organization of a network or corresponding complex system with elements represented as vertices and interactions as edges in a (directed, weighted) graph. Although the notion of clustering can be somewhat…

Machine Learning · Statistics 2017-11-15 Yongjin Park , Joel S. Bader

Synchronization and localization are critical challenges for the coherent functioning of a wireless network, which are conventionally solved independently. Recently, various estimators have been proposed for pairwise synchronization between…

Applications · Statistics 2015-04-15 Raj Thilak Rajan , Alle-Jan van der Veen

The renormalization group (RG) is an essential technique in statistical physics and quantum field theory, which considers scale-invariant properties of physical theories and how these theories' parameters change with scaling. Deep learning…

Statistical Mechanics · Physics 2023-08-23 Kelsie Taylor

Cryogenic electron microscopy (cryo-EM) provides a unique opportunity to study the structural heterogeneity of biomolecules. Being able to explain this heterogeneity with atomic models would help our understanding of their functional…

We present a new type of cluster algorithm that strongly reduces critical slowing down in simulations of vertex models. Since the clusters are closed paths of bonds, we call it the {\em loop algorithm}. The basic steps in constructing a…

Condensed Matter · Physics 2009-01-23 H. G. Evertz , G. Lana , M. Marcu

Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macromolecules. In a cryo-EM experiment, the microscope produces…

Information Theory · Computer Science 2022-10-28 Tamir Bendory , Nicolas Boumal , William Leeb , Eitan Levin , Amit Singer

We explore the role of group symmetries in binary classification tasks, presenting a novel framework that leverages the principles of Neyman-Pearson optimality. Contrary to the common intuition that larger symmetry groups lead to improved…

Machine Learning · Computer Science 2024-08-19 Vishal S. Ngairangbam , Michael Spannowsky

Combinatorial optimization algorithms which compute exact ground state configurations in disordered magnets are seen to exhibit critical slowing down at zero temperature phase transitions. Using arguments based on the physical picture of…

Disordered Systems and Neural Networks · Physics 2009-11-07 A. Alan Middleton

We develop a Machine-Learning Renormalization Group (MLRG) algorithm to explore and analyze many-body lattice models in statistical physics. Using the representation learning capability of generative modeling, MLRG automatically learns the…

Statistical Mechanics · Physics 2023-09-13 Wanda Hou , Yi-Zhuang You

This paper addresses the scheduling problem for unrelated crowd workers in mobile social networks, where the required service time for each task varies among the assigned crowd workers. The goal is to minimize the total weighted completion…

Data Structures and Algorithms · Computer Science 2026-03-30 Chi-Yeh Chen

Single-particle cryo-electron microscopy (cryo-EM) is an emerging imaging modality capable of visualizing proteins and macro-molecular complexes at near-atomic resolution. The low electron-doses used to prevent sample radiation damage,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-24 Qinwen Huang , Ye Zhou , Xiaochen Du , Reed Chen , Jianyou Wang , Cynthia Rudin , Alberto Bartesaghi

In this paper, we propose a novel ensembling technique for deep neural networks, which is able to drastically reduce the required memory compared to alternative approaches. In particular, we propose to extract multiple sub-networks from a…

Machine Learning · Computer Science 2022-10-07 Jary Pomponi , Simone Scardapane , Aurelio Uncini

Single particle cryo-electron microscopy (EM) is an increasingly popular method for determining the 3-D structure of macromolecules from noisy 2-D images of single macromolecules whose orientations and positions are random and unknown. One…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 Roy R. Lederman , Amit Singer

The Expectation-Maximization (EM) algorithm is one of the most popular methods used to solve the problem of parametric distribution-based clustering in unsupervised learning. In this paper, we propose to analyze a generalized EM (GEM)…

Optimization and Control · Mathematics 2021-05-19 Sarthak Chatterjee , Orlando Romero , Sérgio Pequito

We consider the unconstrained optimization problem whose objective function is composed of a smooth and a non-smooth conponents where the smooth component is the expectation a random function. This type of problem arises in some interesting…

Optimization and Control · Mathematics 2011-07-01 Qihang Lin , Xi Chen , Javier Pena

Deep metric learning has yielded impressive results in tasks such as clustering and image retrieval by leveraging neural networks to obtain highly discriminative feature embeddings, which can be used to group samples into different classes.…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Ismail Elezi , Jenny Seidenschwarz , Laurin Wagner , Sebastiano Vascon , Alessandro Torcinovich , Marcello Pelillo , Laura Leal-Taixe

In recent years, research on learning with noisy labels has focused on devising novel algorithms that can achieve robustness to noisy training labels while generalizing to clean data. These algorithms often incorporate sophisticated…

Machine Learning · Computer Science 2023-07-12 Hui Kang , Sheng Liu , Huaxi Huang , Jun Yu , Bo Han , Dadong Wang , Tongliang Liu

RecentadvancesinDistributedComputinghighlightmodelsandalgo- rithms for autonomous swarms of mobile robots that self-organize and cooperate to solve global objectives. The overwhelming majority of works so far considers handmade algorithms…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-07-08 Laure Millet , Maria Potop-Butucaru , Nathalie Sznajder , Sébastien Tixeuil