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Lung nodules suffer large variation in size and appearance in CT images. Nodules less than 10mm can easily lose information after down-sampling in convolutional neural networks, which results in low sensitivity. In this paper, a combination…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Benyuan Sun , Zhen Zhou , Fandong Zhang , Xiuli Li , Yizhou Wang

Efficiency of some dimensionality reduction techniques, like lung segmentation, bone shadow exclusion, and t-distributed stochastic neighbor embedding (t-SNE) for exclusion of outliers, is estimated for analysis of chest X-ray (CXR) 2D…

Machine Learning · Computer Science 2018-11-19 Yu. Gordienko , Yu. Kochura , O. Alienin , O. Rokovyi , S. Stirenko , Peng Gang , Jiang Hui , Wei Zeng

Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by…

Machine Learning · Computer Science 2019-04-23 Marysia Winkels , Taco S. Cohen

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

Background and Objective: In pulmonary nodule detection, the first stage, candidate detection, aims to detect suspicious pulmonary nodules. However, detected candidates include many false positives and thus in the following stage, false…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Hyunjun Eun , Daeyeong Kim , Chanho Jung , Changick Kim

Dense annotations, such as segmentation masks, are expensive and time-consuming to obtain, especially for 3D medical images where expert voxel-wise labeling is required. Weakly supervised approaches aim to address this limitation, but often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Richard Petersen , Fredrik Kahl , Jennifer Alvén

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Lung cancer remains one of the most common and deadliest forms of cancer worldwide. The likelihood of successful treatment depends strongly on the stage at which the disease is diagnosed. Therefore, early detection of lung cancer represents…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Volodymyr Sydorskyi

Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the…

Machine Learning · Statistics 2016-10-03 Petros-Pavlos Ypsilantis , Giovanni Montana

Pneumonia remains a leading cause of morbidity and mortality worldwide. Chest X-ray (CXR) imaging is a fundamental diagnostic tool, but traditional analysis relies on time-intensive expert evaluation. Recently, deep learning has shown…

Image and Video Processing · Electrical Eng. & Systems 2024-01-05 Sandeep Angara , Nishith Reddy Mannuru , Aashrith Mannuru , Sharath Thirunagaru

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Medical image synthesis has become an essential strategy for augmenting datasets and improving model generalization in data-scarce clinical settings. However, fine-grained and controllable synthesis remains difficult due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Shuhan Ding , Jingjing Fu , Yu Gu , Naiteek Sangani , Mu Wei , Paul Vozila , Nan Liu , Jiang Bian , Hoifung Poon

This paper presents and validates a novel lung nodule classification algorithm that uses multifractal features found in X-ray images. The proposed method includes a pre-processing step where two enhancement techniques are applied: histogram…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Isabella María Sierra-Ponce , Angela Mireya León-Mecías , Damian Valdés-Santiago

Histopathology image synthesis aims to address the data shortage issue in training deep learning approaches for accurate cancer detection. However, existing methods struggle to produce realistic images that have accurate nuclei boundaries…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Sujata Butte , Haotian Wang , Aleksandar Vakanski , Min Xian

Chest radiography is an effective screening tool for diagnosing pulmonary diseases. In computer-aided diagnosis, extracting the relevant region of interest, i.e., isolating the lung region of each radiography image, can be an essential step…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Hilda Azimi , Jianxing Zhang , Pengcheng Xi , Hala Asad , Ashkan Ebadi , Stephane Tremblay , Alexander Wong

Detection of pulmonary nodules in chest CT imaging plays a crucial role in early diagnosis of lung cancer. Manual examination is highly time-consuming and error prone, calling for computer-aided detection, both to improve efficiency and…

Computer Vision and Pattern Recognition · Computer Science 2018-07-17 Zhongliu Xie

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to…

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

Currently, a central challenge and bottleneck in the deployment and validation of computer-aided diagnosis (CAD) models within the field of medical imaging is data scarcity. For lung cancer, one of the most prevalent types worldwide,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 António Cardoso , Pedro Sousa , Tania Pereira , Hélder P. Oliveira
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