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Early detection of lung cancer in chest radiographs (CXRs) is crucial for improving patient outcomes, yet nodule detection remains challenging due to their subtle appearance and variability in radiological characteristics like size,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Shreshtha Singh , Ashish Mittal , Manoj Tadepalli , Piyush Kumar , Preetham Putha

Chest X-ray (CXR) is the most common examination for fast detection of pulmonary abnormalities. Recently, automated algorithms have been developed to classify multiple diseases and abnormalities in CXR scans. However, because of the limited…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sebastian Guendel , Arnaud Arindra Adiyoso Setio , Sasa Grbic , Andreas Maier , Dorin Comaniciu

Lung cancer is the leading cause of cancer death and early diagnosis is associated with a positive prognosis. Chest X-ray (CXR) provides an inexpensive imaging mode for lung cancer diagnosis. Suspicious nodules are difficult to distinguish…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Michael James Horry , Subrata Chakraborty , Biswajeet Pradhan , Manoranjan Paul , Jing Zhu , Prabal Datta Barua , U. Rajendra Acharya , Fang Chen , Jianlong Zhou

The limited sample size and insufficient diversity of lung nodule CT datasets severely restrict the performance and generalization ability of detection models. Existing methods generate images with insufficient diversity and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lu Cao , Xiquan He , Junying Zeng , Chaoyun Mai , Min Luo

One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Steve Kommrusch , Louis-Noël Pouchet

Detection of pulmonary nodules by CT is used for screening lung cancer in early stages.omputer aided diagnosis (CAD) based on deep-learning method can identify the suspected areas of pulmonary nodules in CT images, thus improving the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Yang Liu , Yue-Jie Hou , Chen-Xin Qin , Xin-Hui Li , Si-Jing Li , Bin Wang , Chi-Chun Zhou

The performance of medical image analysis systems is constrained by the quantity of high-quality image annotations. Such systems require data to be annotated by experts with years of training, especially when diagnostic decisions are…

Computer Vision and Pattern Recognition · Computer Science 2019-02-08 Siqi Liu , Eli Gibson , Sasa Grbic , Zhoubing Xu , Arnaud Arindra Adiyoso Setio , Jie Yang , Bogdan Georgescu , Dorin Comaniciu

Accurate Computer-Assisted Diagnosis, relying on large-scale annotated pathological images, can alleviate the risk of overlooking the diagnosis. Unfortunately, in medical imaging, most available datasets are small/fragmented. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Changhee Han , Yoshiro Kitamura , Akira Kudo , Akimichi Ichinose , Leonardo Rundo , Yujiro Furukawa , Kazuki Umemoto , Yuanzhong Li , Hideki Nakayama

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Jie Yang , Siqi Liu , Sasa Grbic , Arnaud Arindra Adiyoso Setio , Zhoubing Xu , Eli Gibson , Guillaume Chabin , Bogdan Georgescu , Andrew F. Laine , Dorin Comaniciu

PURPOSE: This study aimed to develop a deep learning-based tool to detect and localize lung nodules with chest radiographs(CXRs). We expected it to enhance the efficiency of interpreting CXRs and reduce the possibilities of delayed…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Yang Tai , Yu-Wen Fang , Fang-Yi Su , Jung-Hsien Chiang

Data availability plays a critical role for the performance of deep learning systems. This challenge is especially acute within the medical image domain, particularly when pathologies are involved, due to two factors: 1) limited number of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Dakai Jin , Ziyue Xu , Youbao Tang , Adam P. Harrison , Daniel J. Mollura

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Computed tomography imaging is a standard modality for detecting and assessing lung cancer. In order to evaluate the malignancy of lung nodules, clinical practice often involves expert qualitative ratings on several criteria describing a…

Computer Vision and Pattern Recognition · Computer Science 2016-09-22 Mario Buty , Ziyue Xu , Mingchen Gao , Ulas Bagci , Aaron Wu , Daniel J. Mollura

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Accurate assessment of Lung nodules is a time consuming and error prone ingredient of the radiologist interpretation work. Automating 3D volume detection and segmentation can improve workflow as well as patient care. Previous works have…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Evi Kopelowitz , Guy Engelhard

Convolutional Neural Networks (CNNs) intrinsically requires large-scale data whereas Chest X-Ray (CXR) images tend to be data/annotation-scarce, leading to over-fitting. Therefore, based on our development experience and related work, this…

Image and Video Processing · Electrical Eng. & Systems 2021-06-03 Changhee Han , Takayuki Okamoto , Koichi Takeuchi , Dimitris Katsios , Andrey Grushnikov , Masaaki Kobayashi , Antoine Choppin , Yutaka Kurashina , Yuki Shimahara

The abundance of overlapping anatomical structures appearing in chest radiographs can reduce the performance of lung pathology detection by automated algorithms (CAD) as well as the human reader. In this paper, we present a deep learning…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Ophir Gozes , Hayit Greenspan

Pulmonary nodules may be an early manifestation of lung cancer, the leading cause of cancer-related deaths among both men and women. Numerous studies have established that deep learning methods can yield high-performance levels in the…

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