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Reinforcement Learning offers a framework to learn to choose actions in order to achieve some goal. However, at the nano-scale, thermal fluctuations hamper the learning process. We analyze this regime using the general framework of Markov…

Statistical Mechanics · Physics 2023-12-18 Francesco Boccardo , Olivier Pierre-Louis

Neuromorphic computing is one of the few current approaches that have the potential to significantly reduce power consumption in Machine Learning and Artificial Intelligence. Imam & Cleland presented an odour-learning algorithm that runs on…

Neural and Evolutionary Computing · Computer Science 2023-09-22 Nik Dennler , André van Schaik , Michael Schmuker

Communication signals often comprise an array of colors, lines, spots, notes or odors that are arranged in complex patterns, melodies or blends. Receiver perception is assumed to influence preference and thus the evolution of signal design,…

Populations and Evolution · Quantitative Biology 2019-01-04 Julien P. Renoult , Tamra C. Mendelson

The thermoelectric response of molecular junctions exhibits large fluctuations, as observed in recent experiments [e.g. Malen J. A. {\sl et al.}, Nano Lett. {\bf 10}, 3406 (2009)]. These were attributed to fluctuations in the energy…

Mesoscale and Nanoscale Physics · Physics 2015-06-12 Yonatan Dubi

Locating the source of odor in a turbulent environment - a common behavior for living organisms - is non-trivial because of the random nature of mixing. Here we analyze the statistical physics aspects of the problem and propose an efficient…

Chaotic Dynamics · Physics 2009-11-07 Eugene Balkovsky , Boris I. Shraiman

We simulate the electrical properties of a device realized by a G protein coupled receptor (GPCR), embedded in its membrane and in contact with two metallic electrodes through which an external voltage is applied. To this purpose, recently,…

Quantitative Methods · Quantitative Biology 2009-11-11 C. Pennetta , V. Akimov , E. Alfinito , L. Reggiani , G. Gomila , G. Ferrari , L. Fumagalli , M. Sampietro

Recent advancements in language representation models such as BERT have led to a rapid improvement in numerous natural language processing tasks. However, language models usually consist of a few hundred million trainable parameters with…

Machine Learning · Computer Science 2019-12-12 Mehrdad Valipour , En-Shiun Annie Lee , Jaime R. Jamacaro , Carolina Bessega

Neural responses are highly variable, and some portion of this variability arises from fluctuations in modulatory factors that alter their gain, such as adaptation, attention, arousal, expected or actual reward, emotion, and local metabolic…

Neurons and Cognition · Quantitative Biology 2015-07-08 Neil C. Rabinowitz , Robbe L. T. Goris , Johannes Ballé , Eero P. Simoncelli

We demonstrate a technique based on noise measurements which can be utilized to study dynamical processes in protein assembly. Direct visualization of dynamics in membrane protein system such as bacteriorhodopsin (bR) upon photostimulation…

Chemical Physics · Physics 2015-05-27 Anshuman. J. Das , Sabyasachi Mukhopadhyay , K. S. Narayan

We show that a protein can be trained to recognise multiple conformations, analogous to an associative memory, and provide capacity calculations based on energy fluctuations and information theory. Unlike the linear capacity of a Hopfield…

Soft Condensed Matter · Physics 2007-05-23 Thomas M A Fink , Robin C Ball

A recent Science paper (Bushdid et al, 2014)[1] proposed that humans can discriminate between at least a trillion olfactory stimuli. Here we show that this claim is the result of a fragile estimation framework capable of producing nearly…

Neurons and Cognition · Quantitative Biology 2015-02-19 Richard C. Gerkin , Jason B. Castro

For many organisms, the number of sensory neurons is largely determined during development, before strong environmental cues are present. This is despite the fact that environments can fluctuate drastically both from generation to…

Neurons and Cognition · Quantitative Biology 2018-10-17 Sarah Marzen , Simon DeDeo

Brain can recognize different objects as ones that it has experienced before. The recognition accuracy and its processing time depend on task properties such as viewing condition, level of noise and etc. Recognition accuracy can be well…

Neurons and Cognition · Quantitative Biology 2018-11-27 Hamed Heidari Gorji , Sajjad Zabbah , Reza Ebrahimpour

We present a model of a coupled system of the olfactory bulb and cortex. Odor inputs to the epithelium are transformed to oscillatory bulbar activities. The cortex recognizes the odor by resonating to the bulbar oscillating pattern when the…

Biological Physics · Physics 2007-05-23 Zhaoping Li , John Hertz

Attention mechanism is a fundamental component of the transformer model and plays a significant role in its success. However, the theoretical understanding of how attention learns to select tokens is still an emerging area of research. In…

Machine Learning · Computer Science 2025-05-20 Keitaro Sakamoto , Issei Sato

The application of thermodynamic reasoning in the study of learning systems has a long tradition. Recently, new tools relating perfect thermodynamic adaptation to the adaptation process have been developed. These results, known as…

Statistical Mechanics · Physics 2023-09-07 Pedro Hack , Cecilia Lindig-Leon , Sebastian Gottwald , Daniel A. Braun

Spectrum sensing enables cognitive radio systems to detect unused portions of the radio spectrum and then use them while avoiding interferences to the primary users. Energy detection is one of the most used techniques for spectrum sensing…

Signal Processing · Electrical Eng. & Systems 2018-03-15 Youness Arjoune

We consider the problem of olfactory searches in a turbulent environment. We focus on agents that respond solely to odor stimuli, with no access to spatial perception nor prior information about the odor. We ask whether navigation to a…

Biological Physics · Physics 2025-01-29 Marco Rando , Martin James , Alessandro Verri , Lorenzo Rosasco , Agnese Seminara

Temperature is a widely used hyperparameter in various tasks involving neural networks, such as classification or metric learning, whose choice can have a direct impact on the model performance. Most of existing works select its value using…

Machine Learning · Computer Science 2022-10-19 Benjamin Chamand , Olivier Risser-Maroix , Camille Kurtz , Philippe Joly , Nicolas Loménie

The most important function of proteins may well be to bind to other biomolecules. It has long been felt that kinetic rates of bond formation and dissociation between soluble receptors and ligands might account for most features of the…

Biological Physics · Physics 2008-09-12 Anne Pierres , Joana Vitte , Anne-Marie Benoliel , Pierre Bongrand
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