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Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…

Machine Learning · Computer Science 2025-09-18 Kevin Dradjat , Massinissa Hamidi , Pierre Bartet , Blaise Hanczar

This short paper gives an introduction to a research project to analyze how digital documents are structured and described. Using a phenomenological approach, this research will reveal common patterns that are used in data, independent from…

Digital Libraries · Computer Science 2014-08-12 Jakob Voß

This study explores the self-synchronization problem in DNA coding, specifically addressing single-deletion errors without using delimiters between codewords. We aim to identify the beginning of each codeword without using delimiters,…

Information Theory · Computer Science 2026-03-31 Whan-Hyuk Choi

The vast parallelism, exceptional energy efficiency and extraordinary information inherent in DNA molecules are being explored for computing, data storage and cryptography. DNA cryptography is a emerging field of cryptography. In this paper…

Cryptography and Security · Computer Science 2011-01-14 D. Prabhu , M. Adimoolam

Storing big data directly on a blockchain poses a substantial burden due to the need to maintain a consistent ledger across all nodes. Numerous studies in decentralized storage systems have been conducted to tackle this particular…

Cryptography and Security · Computer Science 2024-10-01 Narges Dadkhah , Xuyang Ma , Katinka Wolter , Gerhard Wunder

Erasure coding techniques are getting integrated in networked distributed storage systems as a way to provide fault-tolerance at the cost of less storage overhead than traditional replication. Redundancy is maintained over time through…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-06-12 Lluis Pamies-Juarez , Frédérique Oggier , Anwitaman Datta

Printing custom DNA sequences is essential to scientific and biomedical research, but the technology can be used to manufacture plagues as well as cures. Just as ink printers recognize and reject attempts to counterfeit money, DNA…

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

DNA replication stands as one of the fundamental biological processes crucial for cellular functioning. Recent experimental developments enable the study of replication dynamics at the single-molecule level for complete genomes,…

Optimization and Control · Mathematics 2024-11-22 Clara Lage , Nelly Pustelnik , Benjamin Audit , Jean-Michel Arbona , Rémi Gribonval

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

Biological Physics · Physics 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

Minimizing data storage poses a significant challenge in large-scale metagenomic projects. In this paper, we present a new method for improving the encoding of FASTQ files generated by metagenomic sequencing. This method incorporates…

Information Theory · Computer Science 2024-01-04 Diogo Pratas , Armando J. Pinho

The persistent storage of big data requires advanced error correction schemes. The classical approach is to use error correcting codes (ECCs). This work studies an alternative approach, which uses the redundancy inherent in data itself for…

Information Theory · Computer Science 2019-10-17 Pulakesh Upadhyaya , Anxiao Jiang

The accelerating growth of global data generation demands data storage platforms that offer high capacity, long lifespan, and low energy consumption beyond the limits of electronic memory technologies. Optical storage provides an attractive…

To simulate long time and length scale processes involving DNA it is necessary to use a coarse-grained description. Here we provide an overview of different approaches to such coarse graining, focussing on those at the nucleotide level that…

In this paper, we consider the decoding of fountain codes where the received symbols may have errors. It is motivated by the application of fountain codes in DNA-based data storage systems where the inner code decoding, which generally has…

Information Theory · Computer Science 2023-01-31 Xuan He , Kui Cai

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

Soft Condensed Matter · Physics 2008-05-02 Nicholas A. Licata

Synthetic DNA can in principle be used for the archival storage of arbitrary data. Because errors are introduced during DNA synthesis, storage, and sequencing, an error-correcting code (ECC) is necessary for error-free recovery of the data.…

Quantitative Methods · Quantitative Biology 2018-12-05 William H. Press , John A. Hawkins

DNA codes have many applications, such as in data storage, DNA computing, etc. Good DNA codes have large sizes and satisfy some certain constraints. In this paper, we present a new construction method for reversible DNA codes. We show that…

Information Theory · Computer Science 2024-03-19 Xueyan Chen , Whan-Hyuk Choi , Hongwei Liu

DNA-Encoded Library (DEL) has proven to be a powerful tool that utilizes combinatorially constructed small molecules to facilitate highly-efficient screening assays. These selection experiments, involving multiple stages of washing,…

Quantitative Methods · Quantitative Biology 2024-02-14 Benson Chen , Mohammad M. Sultan , Theofanis Karaletsos

In the age of the Cloud and so-called Big Data systems must be increasingly flexible, reconfigurable and adaptable to change in addition to being developed rapidly. As a consequence, designing systems to cater for evolution is becoming…

Software Engineering · Computer Science 2014-02-25 Richard McClatchey , Andrew Branson , Jetendr Shamdasani
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