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Personalized chronic care requires the integration of multimodal health data to enable precise, adaptive, and preventive decision-making. Yet most current digital twin (DT) applications remain organ-specific or tied to isolated data types,…

Software Engineering · Computer Science 2025-10-13 Amal Elgammal , Bernd J. Krämer , Michael P. Papazoglou , Mira Raheem

With the fast evolving of cloud computing and artificial intelligence (AI), the concept of digital twin (DT) has recently been proposed and finds broad applications in industrial Internet, IoT, smart city, etc. The DT builds a mirror…

Networking and Internet Architecture · Computer Science 2021-05-18 Tom H. Luan , Ruhan Liu , Longxiang Gao , Rui Li , Haibo Zhou

We introduce DT-ICU, a multimodal digital twin framework for continuous risk estimation in intensive care. DT-ICU integrates variable-length clinical time series with static patient information in a unified multitask architecture, enabling…

Machine Learning · Computer Science 2026-01-13 Wen Guo

Digital twins are emerging in many industries, typically consisting of simulation models and data associated with a specific physical system. One of the main reasons for developing a digital twin, is to enable the simulation of possible…

Machine Learning · Statistics 2021-03-15 Christian Agrell , Kristina Rognlien Dahl , Andreas Hafver

With rapid digitization and digitalization, drawing a fine line between the digital and the physical world has become nearly impossible. It has become essential more than ever to integrate all spheres of life into a single Digital Thread to…

As mobile robots increasingly operate alongside humans in shared workspaces, ensuring safe, efficient, and interpretable Human-Robot Interaction (HRI) has become a pressing challenge. While substantial progress has been devoted to human…

Digital twin (DT) has emerged as a powerful tool to facilitate monitoring, control, and other decision-making tasks in real-world engineering systems. Online update methods have been proposed to update DT models. Considering the degradation…

Computational Engineering, Finance, and Science · Computer Science 2025-03-13 Yifan Tang , Mostafa Rahmani Dehaghani , G. Gary Wang

Digital Twins have been described as beneficial in many areas, such as virtual commissioning, fault prediction or reconfiguration planning. Equipping Digital Twins with artificial intelligence functionalities can greatly expand those…

Machine Learning · Computer Science 2021-08-31 Benjamin Maschler , Dominik Braun , Nasser Jazdi , Michael Weyrich

Cyber attacks targeting Industrial Control Systems (ICS) have become increasingly sophisticated and hard to identify. Detecting such attacks requires integrating low-level behavioral cues with high-level semantic interpretation, a…

Cryptography and Security · Computer Science 2026-04-07 Konstantinos E. Kampourakis , Vasileios Gkioulos , Sokratis Katsikas

The interpretation of deep neural networks (DNNs) has become a key topic as more and more people apply them to solve various problems and making critical decisions. Concept-based explanations have recently become a popular approach for…

Human-Computer Interaction · Computer Science 2021-08-10 Zhenge Zhao , Panpan Xu , Carlos Scheidegger , Liu Ren

Digital twinning of vehicles is an iconic application of digital twins, as the concept of twinning dates back to the twinning of NASA space vehicles. Although digital twins (DTs) in the automotive industry have been recognized for their…

Emerging Technologies · Computer Science 2024-09-23 Robert Klar , Niklas Arvidsson , Vangelis Angelakis

Digital Twins (DT) have become crucial to achieve sustainable and effective smart urban solutions. However, current DT modelling techniques cannot support the dynamicity of these smart city environments. This is caused by the lack of…

Machine Learning · Computer Science 2024-08-30 Lal Verda Cakir , Kubra Duran , Craig Thomson , Matthew Broadbent , Berk Canberk

Digital twins (DT) have received significant attention due to their numerous benefits, such as real-time data analytics and cost reduction in production. DT serves as a fundamental component of many applications, encompassing smart…

Networking and Internet Architecture · Computer Science 2025-05-08 Chen Chen , Zihan Jia , Ze Wang , Lin Cui , Fung Po Tso

In the way towards Industry 4.0, the complexity of the industrial systems increases due to the presence of multiple agents, Cyber-Physical Systems, distributed sensing, and big data introducing unknown dynamics that affect the production…

Signal Processing · Electrical Eng. & Systems 2020-07-09 Jairo Viola , YangQuan Chen

Digital twin networks (DTNs) serve as an emerging facilitator in the industrial networking sector, enabling the management of new classes of services, which require tailored support for improved resource utilization, low latencies and…

Networking and Internet Architecture · Computer Science 2024-05-14 Marco Becattini , Davide Borsatti , Armir Bujari , Laura Carnevali , Andrea Garbugli , Hrant Khachatrian , Theofanis P. Raptis , Daniele Tarchi

Brain digital twins aim to provide faithful, individualized computational representations of brains as dynamical systems, enabling mechanistic understanding and supporting prediction of clinical interventions. Yet current approaches remain…

Computational Engineering, Finance, and Science · Computer Science 2026-04-16 Alexandre Muzy

This paper aims to provide a comprehensive critical overview on how entities and their interactions in Complex Networked Systems (CNS) are modelled across disciplines as they approach their ultimate goal of creating a Digital Twin (DT) that…

Systems and Control · Electrical Eng. & Systems 2022-02-22 Jiaqi Wen , Bogdan Gabrys , Katarzyna Musial

While digital twins (DT) hold promise for providing real-time insights into complex energy assets, much of the current literature either does not offer a clear framework for information exchange between the model and the asset, lacks key…

Machine Learning · Computer Science 2025-07-03 Logan A. Burnett , Umme Mahbuba Nabila , Majdi I. Radaideh

Serving as an emerging and powerful tool, Large Language Model (LLM)-driven Human Digital Twins are showing great potential in healthcare system research. However, its actual simulation ability for complex human psychological traits, such…

Human-Computer Interaction · Computer Science 2025-12-11 Yuzhou Wu , Mingyang Wu , Di Liu , Rong Yin , Kang Li

Digital twin (DT) technology is increasingly used in urban planning, leveraging real-time data integration for environmental monitoring. This paper presents an urban-focused DT that combines computational fluid dynamics simulations with…