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Purpose: The paper introduces a classical model to describe the dynamics of large spin-1/2 ensembles associated with nuclei bound in large molecule structures, commonly referred to as the semi-solid spin pool, and their magnetization…

Purpose: Quantitative magnetization transfer (qMT) imaging can be used to quantify the proportion of protons in a voxel attached to macromolecules. Here, we show that the original qMT balanced steady-state free precession (bSSFP) model is…

Medical Physics · Physics 2022-07-22 Fritz M. Bayer , Peter Jezzard , Michael Bock , Alex K. Smith

Purpose: Development of a generic model-based reconstruction framework for multi-parametric quantitative MRI that can be used with data from different pulse sequences. Methods: Generic nonlinear model-based reconstruction for quantitative…

Medical Physics · Physics 2023-07-21 Nick Scholand , Xiaoqing Wang , Volkert Roeloffs , Sebastian Rosenzweig , Martin Uecker

Since the inception of magnetization transfer (MT) imaging, it has been widely assumed that Henkelman's two spin pools have similar longitudinal relaxation times, which motivated many researchers to constrain them to each other. However,…

We propose a signal acquisition and modeling framework for multi-component tissue quantification that encompasses transmit field inhomogeneity, multi-component relaxation and magnetization transfer (MT) effects. By applying off-resonance…

Medical Physics · Physics 2025-10-08 Albert Jang , Hyungseok Jang , Nian Wang , Alexey Samsonov , Fang Liu

Quantum estimation involving multiple parameters remains an important problem of both theoretical and practical interest. In this work, we study the problem of simultaneous estimation of two parameters that are respectively associate with…

Quantum Physics · Physics 2022-03-25 Yink Loong Len

Quantitative magnetic resonance imaging (qMRI) is concerned with estimating (in physical units) values of magnetic and tissue parameters e.g., relaxation times $T_1$, $T_2$, or proton density $\rho$. Recently in [Ma et al., Nature, 2013],…

Optimization and Control · Mathematics 2019-03-29 Guozhi Dong , Michael Hintermüller , Kostas Papafitsoros

Purpose: Recent studies have shown that spin-lock MRI can simplify quantitative magnetization transfer (MT) by eliminating its dependency on water pool parameters, removing the need for a T1 map in macromolecular proton fraction (MPF)…

The Bloch Sphere visualization of the possible states of a single qubit has proved a useful pedagogical and conceptual tool as a one-to-one map between qubit states and points in a 3-D space. However, understanding many important concepts…

Quantum Physics · Physics 2024-05-31 Li-Heng Henry Chang , Shea Roccaforte , Ziyu Xu , Paul Cadden-Zimansky

We implement a hybrid quantum-classical model for image classification that compresses MNIST digit images into a low-dimensional feature space and then maps these features onto a 5-qubit quantum state. First, an autoencoder compresses each…

Quantum Physics · Physics 2025-08-01 Soumyadip Sarkar

We propose a theoretical protocol for reconstructing the density matrix of a single-electron spin qubit using spin-polarized transport. The system consists of a quantum dot coupled to ferromagnetic reservoirs and subject to a magnetic field…

Quantum Physics · Physics 2026-04-01 M. B. Sambú , L. Sanz , F. M. Souza

Purpose: Imaging biomarkers with increased myelin specificity are needed to better understand the complex progression of neurological disorders. Inhomogeneous magnetization transfer (ihMT) imaging is an emergent technique that has a high…

In research activities regarding Magnetic Resonance Imaging in medicine, simulation tools with a universal approach are rare. Usually, simulators are developed and used which tend to be restricted to a particular, small range of…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-30 Jürgen Kürsch

Purpose: The analysis of optimized spin ensemble trajectories for relaxometry in the hybrid state. Methods: First, we constructed visual representations to elucidate the differential equation that governs spin dynamics in hybrid state.…

Medical Physics · Physics 2019-06-26 Jakob Assländer , Riccardo Lattanzi , Daniel K Sodickson , Martijn A Cloos

We study the quantum state transfer (QST) of a class of tight-bonding Bloch electron systems with mirror symmetry by considering the mode entanglement. Some rigorous results are obtained to reveal the intrinsic relationship between the…

Quantum Physics · Physics 2009-11-11 Xiao-Feng Qian , Ying Li , Yong Li , Z. Song , C. P. Sun

Quantitative magnetization transfer (qMT) imaging provides myelin-sensitive biomarkers, such as the pool size ratio (PSR), which is valuable for multiple sclerosis (MS) assessment. However, qMT requires specialized 20-30 minute scans. We…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Jiacheng Wang , Hao Li , Xing Yao , Ahmad Toubasi , Taegan Vinarsky , Caroline Gheen , Joy Derwenskus , Chaoyang Jin , Richard Dortch , Junzhong Xu , Francesca Bagnato , Ipek Oguz

Image processing is one of the most promising applications for quantum machine learning (QML). Quanvolutional Neural Networks with non-trainable parameters are the preferred solution to run on current and near future quantum devices. The…

Quantum Physics · Physics 2024-10-10 Daniele Lizzio Bosco , Beatrice Portelli , Giuseppe Serra

The dynamics of large spin-1/2 ensembles in the presence of a varying magnetic field are commonly described by the Bloch equation. Most magnetic field variations result in unintuitive spin dynamics, which are sensitive to small deviations…

Recovery rate prediction plays a pivotal role in bond investment strategies by enhancing risk assessment, optimizing portfolio allocation, improving pricing accuracy, and supporting effective credit risk management. However, accurate…

Computational Finance · Quantitative Finance 2026-01-27 Ying Chen , Paul Griffin , Paolo Recchia , Lei Zhou , Hongrui Zhang

In this work a generic model-based reconstruction for the quantification of relaxation parameters is developed. In contrast to previous approaches that rely on simplified models derived from the Bloch equations, this work includes the Bloch…

Medical Physics · Physics 2019-05-09 Nick Scholand
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