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Accurate medication dosing holds an important position in the overall patient therapeutic process. Therefore, much research has been conducted to develop optimal administration strategy based on Reinforcement learning (RL). However, Relying…

Machine Learning · Computer Science 2025-10-30 Yooseok Lim , Sujee Lee

Causal inference methods are widely applied in various decision-making domains such as precision medicine, optimal policy and economics. Central to causal inference is the treatment effect estimation of intervention strategies, such as…

Artificial Intelligence · Computer Science 2021-05-31 Tri Dung Duong , Qian Li , Guandong Xu

Reinforcement learning (RL) is a powerful framework for learning to take actions to solve tasks. However, in many settings, an agent must winnow down the inconceivably large space of all possible tasks to the single task that it is…

Machine Learning · Computer Science 2020-11-19 Lisa Lee , Benjamin Eysenbach , Ruslan Salakhutdinov , Shixiang Shane Gu , Chelsea Finn

Individualized treatment rules (ITRs) tailor treatments according to individual patient characteristics. They can significantly improve patient care and are thus becoming increasingly popular. The data collected during randomized clinical…

Methodology · Statistics 2015-06-30 Stanislav Minsker , Ying-Qi Zhao , Guang Cheng

Reinforcement learning (RL) has demonstrated its ability to solve high dimensional tasks by leveraging non-linear function approximators. However, these successes are mostly achieved by 'black-box' policies in simulated domains. When…

Machine Learning · Computer Science 2021-11-19 Riad Akrour , Davide Tateo , Jan Peters

Reinforcement Learning (RL) and its integration with deep learning have achieved impressive performance in various robotic control tasks, ranging from motion planning and navigation to end-to-end visual manipulation. However, stability is…

Robotics · Computer Science 2020-07-16 Minghao Han , Lixian Zhang , Jun Wang , Wei Pan

Reinforcement learning (RL) and model predictive control (MPC) offer a wealth of distinct approaches for automatic decision-making under uncertainty. Given the impact both fields have had independently across numerous domains, there is…

Systems and Control · Electrical Eng. & Systems 2025-10-13 Nathan P. Lawrence , Philip D. Loewen , Michael G. Forbes , R. Bhushan Gopaluni , Ali Mesbah

Constrained reinforcement learning is to maximize the expected reward subject to constraints on utilities/costs. However, the training environment may not be the same as the test one, due to, e.g., modeling error, adversarial attack,…

Machine Learning · Computer Science 2022-09-16 Yue Wang , Fei Miao , Shaofeng Zou

Deep reinforcement learning (RL) has shown immense potential for learning to control systems through data alone. However, one challenge deep RL faces is that the full state of the system is often not observable. When this is the case, the…

Machine Learning · Computer Science 2023-10-27 Ian Char , Jeff Schneider

Neural control is an exciting mystery which we instinctively master. Yet, researchers have a hard time explaining the motor control trajectories. Physiologically accurate biomechanical simulations can, to some extent, mimic live subjects…

Signal Processing · Electrical Eng. & Systems 2019-12-10 Amir H. Abdi , Masoud Malakoutian , Thomas Oxland , Sidney Fels

Online reinforcement learning (RL) algorithms offer great potential for personalizing treatment for participants in clinical trials. However, deploying an online, autonomous algorithm in the high-stakes healthcare setting makes quality…

Machine Learning · Computer Science 2024-08-13 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Iris Yan , Finale Doshi-Velez , Susan A. Murphy

Deep reinforcement learning (RL) algorithms can learn complex policies to optimize agent operation over time. RL algorithms have shown promising results in solving complicated problems in recent years. However, their application on…

Machine Learning · Computer Science 2021-09-29 Hamed Khorasgani , Haiyan Wang , Chetan Gupta , Susumu Serita

Reinforcement learning (RL) is gaining attention by more and more researchers in quantitative finance as the agent-environment interaction framework is aligned with decision making process in many business problems. Most of the current…

Mathematical Finance · Quantitative Finance 2022-05-31 Huifang Huang , Ting Gao , Yi Gui , Jin Guo , Peng Zhang

Deep reinforcement learning enables algorithms to learn complex behavior, deal with continuous action spaces and find good strategies in environments with high dimensional state spaces. With deep reinforcement learning being an active area…

Machine Learning · Computer Science 2018-10-17 Winfried Lötzsch

We propose a novel framework to solve risk-sensitive reinforcement learning (RL) problems where the agent optimises time-consistent dynamic spectral risk measures. Based on the notion of conditional elicitability, our methodology constructs…

Machine Learning · Computer Science 2023-05-02 Anthony Coache , Sebastian Jaimungal , Álvaro Cartea

Model-based reinforcement learning attempts to use an available or learned model to improve the data efficiency of reinforcement learning. This work proposes a one-step lookback approach that jointly learns the deep incremental model and…

Robotics · Computer Science 2025-02-28 Cong Li

Recent statistical and reinforcement learning methods have significantly advanced patient care strategies. However, these approaches face substantial challenges in high-stakes contexts, including missing data, inherent stochasticity, and…

Machine Learning · Computer Science 2024-04-02 Harsh Parikh , Quinn Lanners , Zade Akras , Sahar F. Zafar , M. Brandon Westover , Cynthia Rudin , Alexander Volfovsky

The complexity of designing reward functions has been a major obstacle to the wide application of deep reinforcement learning (RL) techniques. Describing an agent's desired behaviors and properties can be difficult, even for experts. A new…

Machine Learning · Computer Science 2024-05-09 Wanqi Xue , Bo An , Shuicheng Yan , Zhongwen Xu

An internet network service provider manages its network with multiple objectives, such as high quality of service (QoS) and minimum computing resource usage. To achieve these objectives, a reinforcement learning-based (RL) algorithm has…

Networking and Internet Architecture · Computer Science 2025-06-17 DongNyeong Heo , Daniela Noemi Rim , Heeyoul Choi

Current neural decoding methods typically aim at explaining behavior based on neural activity via supervised learning. However, since generally there is a strong connection between learning of subjects and their expectations on long-term…