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Interaction-driven modeling of diseases over real-world contact data has been shown to promote the understanding of the spread of diseases in communities. This temporal modeling follows the path-preserving order and timing of the contacts,…

Applications · Statistics 2023-07-13 Yanir Marmor , Alex Abbey , Yuval Shahar , Osnat Mokryn

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

Accurate numbers are needed to understand and predict viral dynamics. Curation of high-quality literature values for the infectious period duration or household secondary attack rate, for example, is especially pressing currently because…

Other Quantitative Biology · Quantitative Biology 2020-07-10 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

To reduce the biases of traditional survey-based methods, this paper proposes an epidemic model-based approach to inference the incubation period distribution of COVID-19 utilizing the publicly reported confirmed case number. We construct…

Populations and Evolution · Quantitative Biology 2020-07-23 Shiyang Lai , Tianqi Zhao , Ningyuan Fan

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

The COVID-19 pandemic is one of the most pressing issues at present. A question which is particularly important for governments and policy makers is the following: Does the virus spread in the same way in different countries? Or are there…

Methodology · Statistics 2020-08-05 Marina Khismatullina , Michael Vogt

The COVID-19 pandemic has affected all countries of the world producing a substantial number of fatalities accompanied by a major disruption in their social, financial, and educational organization. The strict disciplinary measures…

Populations and Evolution · Quantitative Biology 2020-04-28 G. D. Barmparis , G. P. Tsironis

The time varying effective reproduction number is an important parameter for communication and policy decisions during an epidemic. In this paper, we present new statistical methods for estimating the reproduction number based on the…

Methodology · Statistics 2025-10-02 Hans R. Künsch , Fabio Sigrist

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Understanding dynamics of an outbreak like that of COVID-19 is important in designing effective control measures. This study aims to develop an agent based model that compares changes in infection progression by manipulating different…

Populations and Evolution · Quantitative Biology 2021-06-24 Anik Burman , Sayak Chatterjee , Pramit Ghosh , Indranil Mukhokadhyay

Since COVID-19 was first identified in December 2019, various public health interventions have been implemented across the world. As different measures are implemented at different countries at different times, we conduct an assessment of…

Computers and Society · Computer Science 2020-05-15 Xiuyi Fan , Siyuan Liu , Jiarong Chen , Thomas C. Henderson

During the COVID-19 pandemic, different types of non-pharmaceutical interventions played an important role in the efforts to control outbreaks and to limit the spread of the SARS-CoV-2 virus. In certain countries, large-scale voluntary…

Populations and Evolution · Quantitative Biology 2024-09-10 Rasmus Kristoffer Pedersen , Christian Berrig , Tamás Tekeli , Gergely Röst , Viggo Andreasen

During the course of an epidemic, one of the most challenging tasks for authorities is to decide what kind of restrictive measures to introduce and when these should be enforced. In order to take informed decisions in a fully rational…

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

We present a very simple and transparent method to interpret time series of confirmed Covid-19 cases. Roughly speaking, the analysis of weekly new infections for each day is a tool for the definition and early detection of the turning point…

Populations and Evolution · Quantitative Biology 2020-04-13 Christoph Bandt

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

Epidemic forecasts are only as good as the accuracy of epidemic measurements. Is epidemic data, particularly COVID-19 epidemic data, clean and devoid of noise? Common sense implies the negative answer. While we cannot evaluate the…

Populations and Evolution · Quantitative Biology 2023-04-25 Long MA , Piet Van Mieghem , Maksim Kitsak

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

The SIS (susceptible-infected-susceptible) epidemic model on an arbitrary network, without making approximations, is a $2^n$-state Markov chain with a unique absorbing state (the all-healthy state). This makes analysis of the SIS model and,…

Social and Information Networks · Computer Science 2019-01-21 Navid Azizan Ruhi , Christos Thrampoulidis , Babak Hassibi
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