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Endocytosis underlies many cellular functions including signaling and nutrient uptake. The endocytosed cargo gets redistributed across a dynamic network of endosomes undergoing fusion and fission. Here, a theoretical approach is reviewed…

Subcellular Processes · Quantitative Biology 2014-12-04 Lionel Foret , Lutz Brusch , Frank Jülicher

We have generalized the semi-analytic approach of special flow to the description of flows of passive particles taking into account internal noise. The model is represented by a series of recurrence relations. The recurrence relations are…

Statistical Mechanics · Physics 2023-12-12 Boris S. Maryshev , Lyudmila S. Klimenko

Membranes regulate transport in a wide variety of industrial and biological applications. The microscale geometry of the membrane can significantly affect overall transport through the membrane, but the precise nature of this multiscale…

Soft Condensed Matter · Physics 2026-02-02 Molly Brennan , Edwina F. Yeo , Philip Pearce , Mohit P. Dalwadi

We show that particle transport in a uniform, quantum multi-baker map, is generically ballistic in the long time limit, for any fixed value of Planck's constant. However, for fixed times, the semi-classical limit leads to diffusion. Random…

Quantum Physics · Physics 2009-11-07 Daniel K. Wojcik , J. R. Dorfman

Most biochemical reactions in living cells rely on diffusive search for target molecules or regions in a heterogeneous overcrowded cytoplasmic medium. Rapid re-arrangements of the medium constantly change the effective diffusivity felt…

Statistical Mechanics · Physics 2019-11-13 Yann Lanoiselée , Nicolas Moutal , Denis S. Grebenkov

Air transport systems are highly dynamic at temporal scales from minutes to years. This dynamic behavior not only characterizes the evolution of the system but also affect the system's functioning. Understanding the evolutionary mechanisms…

Physics and Society · Physics 2016-05-17 Luis Enrique Correa Rocha

Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Experiments on particles' motion in living cells show that it is often subdiffusive. This subdiffusion may be due to trapping, percolation-like structures, or viscoelatic behavior of the medium. While the models based on trapping (leading…

Disordered Systems and Neural Networks · Physics 2015-06-11 Yasmine Meroz , Igor M. Sokolov , Joseph Klafter

Interaction networks, consisting of agents linked by their interactions, are ubiquitous across many disciplines of modern science. Many methods of analysis of interaction networks have been proposed, mainly concentrating on node degree…

Molecular Networks · Quantitative Biology 2011-12-20 Aleksandar Stojmirović , Yi-Kuo Yu

Complex networks are characterized by latent geometries induced by their topology or by the dynamics on the top of them. In the latter case, different network-driven processes induce distinct geometric features that can be captured by…

Physics and Society · Physics 2021-04-07 Giulia Bertagnolli , Manlio De Domenico

We use a lattice model to study first-passage time distributions of target finding events through complex environments with elongated fibers distributed with different anisotropies and volume occupation fractions. For isotropic systems and…

Statistical Mechanics · Physics 2020-09-10 David Gomez , Eial Teomy , Ayelet Lesman , Yair Shokef

Abridged abstract: Inert interactions between randomly moving entities and spatial disorder play a crucial role in quantifying the diffusive properties of a system. These interactions affect only the movement of the entities, and examples…

Statistical Mechanics · Physics 2022-09-20 Seeralan Sarvaharman , Luca Giuggioli

This paper deals with simulation of flow and transport in porous media such as transport of groundwater contaminants. We first discuss how macro scale equations are derived and which terms have to be closed by models. The transport of…

Numerical Analysis · Mathematics 2018-07-03 Quanji Cai , Sheema Kooshapur , Michael Manhart , Ralf-Peter Mundani , Ernst Rank , Andreas Springer , Boris Vexler

We study the crossing time statistic of diffusing point particles between the two ends of expanding and narrowing two-dimensional conical channels under a transverse external gravitational field. The theoretical expression for the mean…

Statistical Mechanics · Physics 2023-01-11 Ivan Pompa-Garcia , Rodrigo Castilla , Ralf Metzler , Leonardo Dagdug

Single-particle tracking allows to infer the motion of single molecules in living cells. When we observe a long trajectory (more than 100 points), it is possible that the particle switches mode of motion over time. Then, fitting a single…

Methodology · Statistics 2018-04-16 Vincent Briane , Charles Kervrann , Myriam Vimond

We investigate the problem of locating the source of diffusion in complex networks without complete knowledge of nodes' states. Some currently known methods assume the information travels via a single, shortest path, which by assumption is…

Physics and Society · Physics 2019-01-14 Łukasz Gajewski , Krzysztof Suchecki , Janusz Hołyst

Diffusive transport is a universal phenomenon, throughout both biological and physical sciences, and models of diffusion are routinely used to interrogate diffusion-driven processes. However, most models neglect to take into account the…

Quantitative Methods · Quantitative Biology 2015-10-28 Paul R. Taylor , Christian A. Yates , Matthew J. Simpson , Ruth E. Baker

In recent years, the study of biological transportation networks has attracted significant interest, focusing on their self-regulating, demand-driven nature. This paper examines a mathematical model for these networks, featuring nonlinear…

Analysis of PDEs · Mathematics 2024-08-29 Clarissa Astuto , Peter Markowich , Simone Portaro , Giovanni Russo

We consider a basic one-dimensional model of diffusion which allows to obtain a diversity of diffusive regimes whose speed depends on the moments of the per-site trapping time. This model is closely related to the continuous time random…

Probability · Mathematics 2019-03-08 Elena Floriani , Ricardo Lima , Edgardo Ugalde
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