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A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

Machine learning algorithms generally suffer from a problem of explainability. Given a classification result from a model, it is typically hard to determine what caused the decision to be made, and to give an informative explanation. We…

Machine Learning · Computer Science 2019-06-26 Jonathan Moore , Nils Hammerla , Chris Watkins

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

Obtaining automated preliminary read reports for common exams such as chest X-rays will expedite clinical workflows and improve operational efficiencies in hospitals. However, the quality of reports generated by current automated approaches…

Explainable Artificial Intelligence (XAI) has emerged as a critical area of research to unravel the opaque inner logic of (deep) machine learning models. Among the various XAI techniques proposed in the literature, counterfactual…

Artificial Intelligence · Computer Science 2025-01-28 Flavio Giorgi , Cesare Campagnano , Fabrizio Silvestri , Gabriele Tolomei

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

Deep learning methods for chest X-ray interpretation typically rely on pretrained models developed for ImageNet. This paradigm assumes that better ImageNet architectures perform better on chest X-ray tasks and that ImageNet-pretrained…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Alexander Ke , William Ellsworth , Oishi Banerjee , Andrew Y. Ng , Pranav Rajpurkar

Training robust deep learning (DL) systems for disease detection from medical images is challenging due to limited images covering different disease types and severity. The problem is especially acute, where there is a severe class…

Computer Vision and Pattern Recognition · Computer Science 2019-05-01 Behzad Bozorgtabar , Dwarikanath Mahapatra , Hendrik von Teng , Alexander Pollinger , Lukas Ebner , Jean-Phillipe Thiran , Mauricio Reyes

The automatic diagnosis of chest diseases is a popular and challenging task. Most current methods are based on convolutional neural networks (CNNs), which focus on local features while neglecting global features. Recently, self-attention…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xinran Li , Yu Liu , Xiujuan Xu , Xiaowei Zhao

Explanation techniques that synthesize small, interpretable changes to a given image while producing desired changes in the model prediction have become popular for introspecting black-box models. Commonly referred to as counterfactuals,…

Machine Learning · Computer Science 2021-10-06 Jayaraman J. Thiagarajan , Vivek Narayanaswamy , Deepta Rajan , Jason Liang , Akshay Chaudhari , Andreas Spanias

In order to bridge the gap between Deep Learning researchers and medical professionals we develop a very accessible free prototype system which can be used by medical professionals to understand the reality of Deep Learning tools for chest…

Computer Vision and Pattern Recognition · Computer Science 2020-02-04 Joseph Paul Cohen , Paul Bertin , Vincent Frappier

Explaining the predictions of a deep neural network is a nontrivial task, yet high-quality explanations for predictions are often a prerequisite for practitioners to trust these models. Counterfactual explanations aim to explain predictions…

Machine Learning · Computer Science 2025-01-16 Andreas Abildtrup Hansen , Paraskevas Pegios , Anna Calissano , Aasa Feragen

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Deep graph learning models have demonstrated remarkable capabilities in processing graph-structured data and have been widely applied across various fields. However, their complex internal architectures and lack of transparency make it…

Machine Learning · Computer Science 2026-01-27 Jinlong Hu , Jiacheng Liu

Convolutional neural networks (CNNs) learn abstract features to perform object classification, but understanding these features remains challenging due to difficult-to-interpret results or high computational costs. We propose an automatic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Maren H. Wehrheim , Pamela Osuna-Vargas , Matthias Kaschube

Deep learning is the state-of-the-art for medical imaging tasks, but requires large, labeled datasets. For risk prediction, large datasets are rare since they require both imaging and follow-up (e.g., diagnosis codes). However, the release…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Yanru Chen , Michael T Lu , Vineet K Raghu

The recent trend of integrating multi-source Chest X-Ray datasets to improve automated diagnostics raises concerns that models learn to exploit source-specific correlations to improve performance by recognizing the source domain of an image…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Srishti Gautam , Marina M. -C. Höhne , Stine Hansen , Robert Jenssen , Michael Kampffmeyer

We propose an architecture for training generative models of counterfactual conditionals of the form, 'can we modify event A to cause B instead of C?', motivated by applications in robot control. Using an 'adversarial training' paradigm, an…

Robotics · Computer Science 2020-09-23 Simón C. Smith , Subramanian Ramamoorthy

The inversion of real images into StyleGAN's latent space is a well-studied problem. Nevertheless, applying existing approaches to real-world scenarios remains an open challenge, due to an inherent trade-off between reconstruction and…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Yuval Alaluf , Omer Tov , Ron Mokady , Rinon Gal , Amit H. Bermano

The development of larger models for medical image analysis has led to increased performance. However, it also affected our ability to explain and validate model decisions. Models can use non-relevant parts of images, also called spurious…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Théo Sourget , Michelle Hestbek-Møller , Amelia Jiménez-Sánchez , Jack Junchi Xu , Veronika Cheplygina
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