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This study aimed to propose a denoising method for dynamic contrast-enhanced computed tomography (DCE-CT) perfusion studies using a three-dimensional deep image prior (DIP), and to investigate its usefulness in comparison with total…

Medical Physics · Physics 2023-04-04 Kenya Murase

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Dongkyu Won , Euijin Jung , Sion An , Philip Chikontwe , Sang Hyun Park

Cone Beam Computed Tomography(CBCT) is a now known method to conduct CT imaging. Especially, The Low Dose CT imaging is one of possible options to protect organs of patients when conducting CT imaging. Therefore Low Dose CT imaging can be…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Wooram Kang , Mayank Patwari

Low-dose computed tomography (LDCT) became a clear trend in radiology with an aspiration to refrain from delivering excessive X-ray radiation to the patients. The reduction of the radiation dose decreases the risks to the patients but…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Nonlinear bilateral filters (BF) deliver a fine blend of computational simplicity and blur-free denoising. However, little is known about their nature, noise-suppressing properties, and optimal choices of filter parameters. Our study is…

Computer Vision and Pattern Recognition · Computer Science 2010-07-08 Oleg S. Pianykh

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second…

Machine Learning · Statistics 2018-03-29 Eunhee Kang , Jaejun Yoo , Jong Chul Ye

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Low Dose Computed Tomography (LDCT) has offered tremendous benefits in radiation restricted applications, but the quantum noise as resulted by the insufficient number of photons could potentially harm the diagnostic performance. Current…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Xin Yi , Paul Babyn

Low-dose CT (LDCT) imaging attracted a considerable interest for the reduction of the object's exposure to X-ray radiation. In recent years, supervised deep learning (DL) has been extensively studied for LDCT image reconstruction, which…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Qiaoqiao Ding , Hui Ji , Yuhui Quan , Xiaoqun Zhang

The remarkable success of deep learning methods in solving computer vision problems, such as image classification, object detection, scene understanding, image segmentation, etc., has paved the way for their application in biomedical…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Prabhat Kc , Rongping Zeng

Deep learning has been successfully applied to low-dose CT (LDCT) image denoising for reducing potential radiation risk. However, the widely reported supervised LDCT denoising networks require a training set of paired images, which is…

Machine Learning · Computer Science 2023-02-09 Yuhui Ruan , Qiao Yuan , Chuang Niu , Chen Li , Yudong Yao , Ge Wang , Yueyang Teng

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

In the past few decades, to reduce the risk of X-ray in computed tomography (CT), low-dose CT image denoising has attracted extensive attention from researchers, which has become an important research issue in the field of medical images.…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Tengfei Liang , Yi Jin , Yidong Li , Tao Wang , Songhe Feng , Congyan Lang

The recent application of deep learning (DL) to various tasks has seen the performance of classical techniques surpassed by their DL-based counterparts. As a result, DL has equally seen application in the removal of noise from images. In…

Image and Video Processing · Electrical Eng. & Systems 2021-07-15 Basit O. Alawode , Motaz Alfarraj

Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Medical Physics · Physics 2020-05-21 Dufan Wu , Hui Ren , Quanzheng Li

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method…

Medical Physics · Physics 2016-10-04 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang