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Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

Quantitative Methods · Quantitative Biology 2018-02-06 M. De Domenico

Despite their topological complexity almost all functional properties of metabolic networks can be derived from steady-state dynamics. Indeed, many theoretical investigations (like flux-balance analysis) rely on extracting function from…

Molecular Networks · Quantitative Biology 2009-11-13 Carsten Marr , Mark Mueller-Linow , Marc-Thorsten Huett

Complex networks pervade various real-world systems, from the natural environment to human societies. The essence of these networks is in their ability to transition and evolve from microscopic disorder-where network topology and node…

Social and Information Networks · Computer Science 2025-06-10 Jingtao Ding , Chang Liu , Yu Zheng , Yunke Zhang , Zihan Yu , Ruikun Li , Hongyi Chen , Jinghua Piao , Huandong Wang , Jiazhen Liu , Yong Li

A simple and accurate relationship is demonstrated that links the average shortest path, nodes, and edges in a complex network. This relationship takes advantage of the concept of link density and shows a large improvement in fitting…

Physics and Society · Physics 2013-04-24 Reginald D. Smith

Neural networks show a progressive increase in complexity during the time course of evolution. From diffuse nerve nets in Cnidaria to modular, hierarchical systems in macaque and humans, there is a gradual shift from simple processes…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser , Sreedevi Varier

Dynamical patterns in complex networks of coupled oscillators are both of theoretical and practical interest, yet to fully reveal and understand the interplay between pattern emergence and network structure remains to be an outstanding…

Chaotic Dynamics · Physics 2017-04-03 Dongmei Song , Yafeng Wang , Xiang Gao , Shi-Xian Qu , Ying-Cheng Lai , Xingang Wang

Network theory has unveiled the underlying structure of complex systems such as the Internet or the biological networks in the cell. It has identified universal properties of complex networks, and the interplay between their structure and…

Physics and Society · Physics 2015-09-21 Ginestra Bianconi

It is widely accepted that the complex dynamics characteristic of recurrent neural circuits contributes in a fundamental manner to brain function. Progress has been slow in understanding and exploiting the computational power of recurrent…

Chaotic Dynamics · Physics 2013-07-18 Rodrigo Laje , Dean V. Buonomano

The observed architecture of ecological and socio-economic networks differs significantly from that of random networks. From a network science standpoint, non-random structural patterns observed in real networks call for an explanation of…

Physics and Society · Physics 2019-05-30 Manuel Sebastian Mariani , Zhuo-Ming Ren , Jordi Bascompte , Claudio Juan Tessone

Over the last decade, random hyperbolic graphs have proved successful in providing geometric explanations for many key properties of real-world networks, including strong clustering, high navigability, and heterogeneous degree…

Physics and Society · Physics 2023-03-01 Béatrice Désy , Patrick Desrosiers , Antoine Allard

The proliferation of networked devices, systems, and applications that we depend on every day makes managing networks more important than ever. The increasing security, availability, and performance demands of these applications suggest…

Networking and Internet Architecture · Computer Science 2017-11-01 Nick Feamster , Jennifer Rexford

To understand the formation, evolution, and function of complex systems, it is crucial to understand the internal organization of their interaction networks. Partly due to the impossibility of visualizing large complex networks, resolving…

Physics and Society · Physics 2011-11-30 Takashi Nishikawa , Adilson E. Motter

Human navigation has been of interest to psychologists and cognitive scientists since the past few decades. It was in the recent past that a study of human navigational strategies was initiated with a network analytic approach, instigated…

Data Structures and Algorithms · Computer Science 2013-05-08 Rishi Ranjan Singh , Shreyas Balakuntala , Sudarshan Iyengar

To comprehend the multipartite organization of large-scale biological and social systems, we introduce a new information theoretic approach that reveals community structure in weighted and directed networks. The method decomposes a network…

Physics and Society · Physics 2008-02-13 M. Rosvall , C. T. Bergstrom

Supplementing a lattice with long-range connections effectively models small-world networks characterized by a high local and global interconnectedness observed in systems ranging from society to the brain. If the links have a wiring cost…

Disordered Systems and Neural Networks · Physics 2007-05-23 Thomas Petermann , Paolo De Los Rios

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

Many networks describing complex systems are directed: the interactions between elements are not symmetric. Recent work has shown that these networks can display properties such as trophic coherence or non-normality, which in turn affect…

Physics and Society · Physics 2019-08-21 Samuel Johnson

The concept of 'complexity' plays a central role in complex network science. Traditionally, this term has been taken to express heterogeneity of the node degrees of a therefore complex network. However, given that the degree distribution is…

Physics and Society · Physics 2021-07-01 Éverton F. da Cunha , Luciano da F. Costa

The study of complex networks is a significant development in modern science, and has enriched the social sciences, biology, physics, and computer science. Models and algorithms for such networks are pervasive in our society, and impact…

Machine Learning · Computer Science 2022-06-08 C. Seshadhri , Aneesh Sharma , Andrew Stolman , Ashish Goel

The topology of any complex system is key to understanding its structure and function. Fundamentally, algebraic topology guarantees that any system represented by a network can be understood through its closed paths. The length of each path…

Methodology · Statistics 2017-05-17 Pierre-André G. Maugis , Sofia C. Olhede , Patrick J. Wolfe