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Background: In medical imaging, prior studies have demonstrated disparate AI performance by race, yet there is no known correlation for race on medical imaging that would be obvious to the human expert interpreting the images. Methods:…

In medical imaging, artificial intelligence (AI) is increasingly being used to automate routine tasks. However, these algorithms can exhibit and exacerbate biases which lead to disparate performances between protected groups. We investigate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Tiarna Lee , Esther Puyol-Antón , Bram Ruijsink , Keana Aitcheson , Miaojing Shi , Andrew P. King

One of the critical challenges in machine learning applications is to have fair predictions. There are numerous recent examples in various domains that convincingly show that algorithms trained with biased datasets can easily lead to…

Machine Learning · Computer Science 2020-06-18 Samaneh Abbasi-Sureshjani , Ralf Raumanns , Britt E. J. Michels , Gerard Schouten , Veronika Cheplygina

Background: Breast density, as derived from mammographic images and defined by the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS), is one of the strongest risk factors for breast cancer. Breast ultrasound…

Artificial Intelligence (AI) has demonstrated success in computational pathology (CPath) for disease detection, biomarker classification, and prognosis prediction. However, its potential to learn unintended demographic biases, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shengjia Chen , Ruchika Verma , Kevin Clare , Jannes Jegminat , Eugenia Alleva , Kuan-lin Huang , Brandon Veremis , Thomas Fuchs , Gabriele Campanella

While deep learning has shown promise in improving the automated diagnosis of disease based on chest X-rays, deep networks may exhibit undesirable behavior related to shortcuts. This paper studies the case of spurious class skew in which…

Computer Vision and Pattern Recognition · Computer Science 2020-09-23 Sarah Jabbour , David Fouhey , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

In computer vision there has been significant research interest in assessing potential demographic bias in deep learning models. One of the main causes of such bias is imbalance in the training data. In medical imaging, where the potential…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Tiarna Lee , Esther Puyol-Anton , Bram Ruijsink , Miaojing Shi , Andrew P. King

The subject of "fairness" in artificial intelligence (AI) refers to assessing AI algorithms for potential bias based on demographic characteristics such as race and gender, and the development of algorithms to address this bias. Most…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Esther Puyol-Anton , Bram Ruijsink , Stefan K. Piechnik , Stefan Neubauer , Steffen E. Petersen , Reza Razavi , Andrew P. King

Recent studies have demonstrated that deep learning models can discriminate based on protected classes like race and gender. In this work, we evaluate bias present in deepfake datasets and detection models across protected subgroups. Using…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Loc Trinh , Yan Liu

As artificial intelligence (AI) rapidly approaches human-level performance in medical imaging, it is crucial that it does not exacerbate or propagate healthcare disparities. Prior research has established AI's capacity to infer demographic…

Computers and Society · Computer Science 2023-12-19 Yuzhe Yang , Haoran Zhang , Judy W Gichoya , Dina Katabi , Marzyeh Ghassemi

This work reveals undiscovered challenges in the performance and generalizability of deep learning models. We (1) identify spurious shortcuts and evaluation issues that can inflate performance and (2) propose training and analysis methods…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Trevor Tsue , Brent Mombourquette , Ahmed Taha , Thomas Paul Matthews , Yen Nhi Truong Vu , Jason Su

Advances in artificial intelligence (AI) have achieved expert-level performance in medical imaging applications. Notably, self-supervised vision-language foundation models can detect a broad spectrum of pathologies without relying on…

Computers and Society · Computer Science 2024-02-23 Yuzhe Yang , Yujia Liu , Xin Liu , Avanti Gulhane , Domenico Mastrodicasa , Wei Wu , Edward J Wang , Dushyant W Sahani , Shwetak Patel

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun

Despite the great promise that machine learning has offered in many fields of medicine, it has also raised concerns about potential biases and poor generalization across genders, age distributions, races and ethnicities, hospitals, and data…

Machine Learning · Computer Science 2023-02-01 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

We externally validated three deep learning models (DenseNet121, ViT-B/32, and ResNet50) for predicting mammographic breast density from breast ultrasound exams on an independent cohort. The external validation set comprised 2,000…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Yuxuan Chen , Arianna Bunnell , Yanqi Xu , Haoyan Yang , Thomas K. Wolfgruber , John A. Shepherd , Yiqiu Shen

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Deep Learning models have achieved remarkable success. Training them is often accelerated by building on top of pre-trained models which poses the risk of perpetuating encoded biases. Here, we investigate biases in the representations of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Valerie Krug , Sebastian Stober

Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…

We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…

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