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Performing optimal Bayesian design for discriminating between competing models is computationally intensive as it involves estimating posterior model probabilities for thousands of simulated datasets. This issue is compounded further when…

Methodology · Statistics 2022-04-07 Markus Hainy , David J. Price , Olivier Restif , Christopher Drovandi

Making good predictions of a physical system using a computer code requires the inputs to be carefully specified. Some of these inputs called control variables have to reproduce physical conditions whereas other inputs, called parameters,…

Computation · Statistics 2018-04-04 Guillaume Damblin , Pierre Barbillon , Merlin Keller , Alberto Pasanisi , Eric Parent

Compressed sensing applied to magnetic resonance imaging (MRI) allows to reduce the scanning time by enabling images to be reconstructed from highly undersampled data. In this paper, we tackle the problem of designing a sampling mask for an…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Thomas Sanchez , Baran Gözcü , Ruud B. van Heeswijk , Armin Eftekhari , Efe Ilıcak , Tolga Çukur , Volkan Cevher

Power and sample size analysis comprises a critical component of clinical trial study design. There is an extensive collection of methods addressing this problem from diverse perspectives. The Bayesian paradigm, in particular, has attracted…

Methodology · Statistics 2021-12-08 Jane Pan , Sudipto Banerjee

We address the problem of Bayesian reinforcement learning using efficient model-based online planning. We propose an optimism-free Bayes-adaptive algorithm to induce deeper and sparser exploration with a theoretical bound on its performance…

Machine Learning · Computer Science 2020-06-30 Divya Grover , Debabrota Basu , Christos Dimitrakakis

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ana Lawry Aguila , Dina Zemlyanker , You Cheng , Sudeshna Das , Daniel C. Alexander , Oula Puonti , Annabel Sorby-Adams , W. Taylor Kimberly , Juan Eugenio Iglesias

We propose to use Bayesian optimization (BO) to improve the efficiency of the design selection process in clinical trials. BO is a method to optimize expensive black-box functions, by using a regression as a surrogate to guide the search.…

Methodology · Statistics 2021-05-20 Jakob Richter , Tim Friede , Jörg Rahnenführer

The present paper studies so-called deep image prior (DIP) techniques in the context of ill-posed inverse problems. DIP networks have been recently introduced for applications in image processing; also first experimental results for…

Machine Learning · Computer Science 2020-03-19 Sören Dittmer , Tobias Kluth , Peter Maass , Daniel Otero Baguer

Cone-Beam Computed Tomography (CBCT) is an indispensable technique in medical imaging, yet the associated radiation exposure raises concerns in clinical practice. To mitigate these risks, sparse-view reconstruction has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Yiqun Lin , Hualiang Wang , Jixiang Chen , Xiaomeng Li

Design optimisation offers the potential to develop lightweight aircraft structures with reduced environmental impact. Due to the high number of design variables and constraints, these challenges are typically addressed using gradient-based…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Hauke F. Maathuis , Roeland De Breuker , Saullo G. P. Castro

Leveraging the wealth of unlabeled data produced in recent years provides great potential for improving supervised models. When the cost of acquiring labels is high, probabilistic active learning methods can be used to greedily select the…

Machine Learning · Statistics 2021-02-09 Robert Pinsler , Jonathan Gordon , Eric Nalisnick , José Miguel Hernández-Lobato

We consider the problem of learning the structure of a high dimensional precision matrix under sparsity assumptions. We propose to use a shrinkage prior, called the DL-graphical prior based on the Dirichlet-Laplace prior used for the…

Statistics Theory · Mathematics 2019-08-08 Sayantan Banerjee

Design of printed circuit board (PCB) stack-up requires the consideration of characteristic impedance, insertion loss and crosstalk. As there are many parameters in a PCB stack-up design, the optimization of these parameters needs to be…

Other Statistics · Statistics 2019-11-12 Jiayi He , Aravind Sampath Kumar , Arun Chada , Bhyrav Mutnury , James Drewniak

Modern approaches to perform Bayesian variable selection rely mostly on the use of shrinkage priors. That said, an ideal shrinkage prior should be adaptive to different signal levels, ensuring that small effects are ruled out, while keeping…

Methodology · Statistics 2024-11-14 Santiago Marin , Bronwyn Loong , Anton H. Westveld

This paper proposes a new methodology for performing Bayesian inference in imaging inverse problems where the prior knowledge is available in the form of training data. Following the manifold hypothesis and adopting a generative modelling…

Methodology · Statistics 2021-03-19 Matthew Holden , Marcelo Pereyra , Konstantinos C. Zygalakis

Performing X-ray computed tomography (CT) examinations with less radiation has recently received increasing interest: in medical imaging this means less (potentially harmful) radiation for the patient; in non-destructive testing of…

Medical Physics · Physics 2018-09-25 Dragos Trinca , Eduard Libin

Optimal design of a Phase I cancer trial can be formulated as a stochastic optimization problem. By making use of recent advances in approximate dynamic programming to tackle the problem, we develop an approximation of the Bayesian optimal…

Methodology · Statistics 2010-12-01 Jay Bartroff , Tze Leung Lai

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Chenyu Shen , Wenjun Xia , Hongwei Ye , Mingzheng Hou , Hu Chen , Yan Liu , Jiliu Zhou , Yi Zhang

Sampling one or more effective solutions from large search spaces is a recurring idea in machine learning, and sequential optimization has become a popular solution. Typical examples include data summarization, sample mining for predictive…

Coherent diffractive imaging (CDI), using both X-rays and electrons, has made extremely rapid progress over the past two decades. The associated reconstruction algorithms are typically iterative, and seeded with a crude first estimate. A…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Konstantin M. Pavlov , Kaye S. Morgan , Vasily I. Punegov , David M. Paganin
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