Related papers: Action potential solitons and waves in axons
We suggest that the propagation of the action potential is driven by a pressure pulse propagating in the axoplasm along the axon length. The pressure pulse mechanically activates Na ion channels embedded in the axon membrane. This…
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length. The pressure pulse stretch-modulates voltage-gated Na (Nav) channels embedded in…
In an ongoing debate on the physical nature of the action potential, one group adheres to the electrical model of Hodgkin and Huxley, while the other describes the action potential as a non-linear acoustic pulse propagating within an…
The soliton wave model of action potentials, and the proposal of induced lipid pores, are potentially paradigm shifting ideas which challenge accepted views of the Hodgkin-Huxley model and of protein-based ion channels. These two proposals…
We demonstrate that our recently developed theory of electric field wave propagation in anisotropic and inhomogeneous brain tissues, which has been shown to explain a broad range of observed coherent synchronous brain electrical processes,…
Here a viable and never before investigated mechanism of propagation of spikes along neurons is proposed. In the following, velocity of propagation of small-amplitude pressure waves through the cytoplasmic interior of myelinated and…
Many studies have shown that a mechanical displacement of the axonal membrane accompanies the electrical pulse defining the Action Potential (AP). Despite a large and diverse body of experimental evidence, there is no theoretical consensus…
In this paper, we analyze the effect of the redistribution of the transmembrane ion channels in the axon caused by longitudinal acoustic vibrations of the membrane. These oscillations can be excited by an external source of ultrasound and…
By extending the crude Goldman-Hodgkin-Katz electrodiffusion model for resting-state membrane potentials in perfused giant axons of squid, we reformulate the Hodgkin-Huxley (HH) phenomenological quantitative model to create a new model…
We introduce a method for computing probabilities for spontaneous activity and propagation fail- ure of the action potential in spatially extended, conductance-based neuronal models subject to channel noise, based on statistical properties…
Action potential generation underlies some of the most consequential dynamical systems on Earth, from brains to hearts. It is therefore interesting to develop synthetic cell-free systems, based on the same molecular mechanisms, which may…
This work proposes a two-dimensional electrophysiological model for describing neuronal responses to external electric stimuli under patch-clamped conditions. Our proposed model successfully captures the key features of the Hodgkin-Huxley…
Stimulated by ongoing discussions about the relevance of mechanical motion in the propagation of nerve signals capillary waves of water-based electrolytes in elastic tubular systems are considered as an essential ingredient. Their…
Vortex filaments are highly rotating localized structures of fluids that admits several types of excitation. Here, we study them by using numerical simulations of the three-dimensional incompressible Navier-Stokes equations. We first…
A quantitative description of pulses and wave trains in the spatially discrete Hodgkin-Huxley model for myelinated nerves is given. Predictions of the shape and speed of the waves and the thresholds for propagation failure are obtained. Our…
Comprehending the nature of action potentials is fundamental to our understanding of the functioning of nervous systems in general. Here we consider their evolution and describe their functions of communication, modulation and computation…
We examine a collection of particles interacting with inverse-square two-body potentials in the thermodynamic limit. We find explicit large-amplitude density waves and soliton solutions for the motion of the system. Waves can be constructed…
The collisions of two simultaneously generated impulses in the giant axons of both earthworms and lobster propagating in orthodromic and antidromic direction were investigated. The experiments have been performed on the extracted ventral…
In a succession of articles published over 65 years ago, Sir Alan Lloyd Hodgkin and Sir Andrew Fielding Huxley established what now forms our physical understanding of excitation in nerve, and how the axon conducts the action potential.…
The Artificial Axon is a unique synthetic system, based on biomolecular components, which supports action potentials. Here we consider, theoretically, the corresponding space extended system, and discuss the occurrence of solitary waves, or…