Related papers: HelixFold: An Efficient Implementation of AlphaFol…
As LLMs scale to multi-million-token KV histories, real-time autoregressive decoding under tight Token-to-Token Latency (TTL) constraints faces growing pressure. Two core bottlenecks dominate: accessing Feed-Forward Network (FFN) weights…
Protein inverse folding aims to design an amino acid sequence that will fold into a given backbone structure, serving as a central task in protein design. Two main paradigms have been widely explored. Template-based methods exploit…
This study develops a cloud-based deep learning system for early prediction of diabetes, leveraging the distributed computing capabilities of the AWS cloud platform and deep learning technologies to achieve efficient and accurate risk…
Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…
Following AI scaling trends, frontier models continue to grow in size and continue to be trained on larger datasets. Training these models requires huge investments in exascale computational resources, which has in turn driven developtment…
Training recommendation models pose significant challenges regarding resource utilization and performance. Prior research has proposed an approach that categorizes embeddings into popular and non-popular classes to reduce the training time…
Ensembles, where multiple neural networks are trained individually and their predictions are averaged, have been shown to be widely successful for improving both the accuracy and predictive uncertainty of single neural networks. However, an…
Being accurate, efficient, and compact is essential to a facial landmark detector for practical use. To simultaneously consider the three concerns, this paper investigates a neat model with promising detection accuracy under wild…
Time series imputation benefits from leveraging cross-feature correlations, yet existing attention-based methods re-discover feature relationships at each layer, lacking persistent anchors to maintain consistent representations. To address…
We break the linear link between the layer size and its inference cost by introducing the fast feedforward (FFF) architecture, a log-time alternative to feedforward networks. We demonstrate that FFFs are up to 220x faster than feedforward…
Diffusion and flow-matching models achieve remarkable generative performance but at the cost of many sampling steps, this slows inference and limits applicability to time-critical tasks. The ReFlow procedure can accelerate sampling by…
While federated learning leverages distributed client resources, it faces challenges due to heterogeneous client capabilities. This necessitates allocating models suited to clients' resources and careful parameter aggregation to accommodate…
We present LFM2, a family of Liquid Foundation Models designed for efficient on-device deployment and strong task capabilities. Using hardware-in-the-loop architecture search under edge latency and memory constraints, we obtain a compact…
As an essential tool of secure distributed machine learning, vertical federated learning (VFL) based on homomorphic encryption (HE) suffers from severe efficiency problems due to data inflation and time-consuming operations. To this core,…
RNA secondary structure prediction is widely used to understand RNA function. Recently, there has been a shift away from the classical minimum free energy (MFE) methods to partition function-based methods that account for folding ensembles…
Maximizing parallelism level in applications can be achieved by minimizing overheads due to load imbalances and waiting time due to memory latencies. Compiler optimization is one of the most effective solutions to tackle this problem. The…
Deploying LLM agents at scale typically requires choosing between quality and cost. Existing cost-reduction approaches fail to preserve agility: the ability to iterate rapidly without human time bottlenecks. Prompt engineering is brittle…
Deep neural networks (DNNs) exploit many layers and a large number of parameters to achieve excellent performance. The training process of DNN models generally handles large-scale input data with many sparse features, which incurs high…
To optimize large Transformer model training, both efficient parallel computing and advanced data management are indispensable. However, current methods often assume a stable and uniform training workload, neglecting data-induced…
Even with the significant advances of AlphaFold-Multimer (AF-Multimer) and AlphaFold3 (AF3) in protein complex structure prediction, their accuracy is still not comparable with monomer structure prediction. Efficient quality assessment (QA)…