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Chromosomes are crumpled polymer chains further folded into a sequence of stochastic loops via loop extrusion. While extrusion has been verified experimentally, the particular means by which the extruding complexes bind DNA polymer remains…

Soft Condensed Matter · Physics 2023-06-14 Kirill Polovnikov , Bogdan Slavov

The coupling between the depolymerization of microtubules (MTs) and the motion of the Dam1 ring complex is now thought to play an important role in the generation of forces during mitosis. Our current understanding of this motion is based…

Subcellular Processes · Quantitative Biology 2010-04-22 Jonathan W. Armond , Matthew S. Turner

We develop a theoretical description of the topological disentanglement occurring when torus knots reach the ends of a semi-flexible polymer under tension. These include decays into simpler knots and total unknotting. The minimal number of…

Statistical Mechanics · Physics 2020-11-04 Michele Caraglio , Boris Marcone , Fulvio Baldovin , Enzo Orlandini , Attilio L. Stella

The equilibrium statistical mechanics of classical directed polymers in 2 dimensions is well known to be equivalent to the imaginary-time quantum dynamics of a 1+1-dimensional many-particle system, with polymer configurations corresponding…

Soft Condensed Matter · Physics 2013-05-30 D. Zeb Rocklin , Shina Tan , Paul M. Goldbart

Circuit topology refers to the arrangement of interactions between objects belonging to a linearly ordered object set. Linearly ordered set of objects are common in nature and occur in a wide range of applications in economics, computer…

Disordered Systems and Neural Networks · Physics 2015-09-02 Alireza Mashaghi , Abolfazl Ramezanpour

Thermally actuated twisted and coiled polymer (TCP) artificial muscles exhibit exceptional specific work capacities but are limited by an inherent competition between load-bearing capacity and actuation stroke. To address this limitation,…

Soft Condensed Matter · Physics 2026-02-09 Ye Xiao , Zhao Luo , Falin Tian , Xinghao Hu , Dabiao Liu , Chun Li

We numerically examine the nonlinear rubber elasticity of topologically constrained polymer networks. We propose a simple and effective model based on Graessley and Pearson's topological model (GP model) for describing the topological…

Soft Condensed Matter · Physics 2015-03-19 Naomi Hirayama , Kyoichi Tsurusaki

The tube model is a central concept in polymer physics, and allows to reduce the complex many-filament problem of an entangled polymer solution to a single filament description. We investigate the probability distribution function of…

Soft Condensed Matter · Physics 2009-08-12 Hauke Hinsch , Erwin Frey

By using the blob theory and computer simulations, we investigate the properties of a linear polymer performing a stationary rotational motion around a long impenetrable rod. In particular, in the simulations the rotation is induced by a…

The viscous flow of polymer chains in dense melts is dominated by topological constraints whenever the single chain contour length, N, becomes larger than the characteristic scale Ne, defining comprehensively the macroscopic rheological…

Soft Condensed Matter · Physics 2023-07-19 Mattia Alberto Ubertini , Angelo Rosa

We present a novel mechanism for resolving the mechanical rigidity of nanoscopic circular polymers that flow in a complex environment. The emergence of a regime of negative differential mobility induced by topological interactions between…

Soft Condensed Matter · Physics 2018-11-21 Stefano Iubini , Enzo Orlandini , Davide Michieletto , Marco Baiesi

For various polymers with different topological structures we numerically evaluate the mean-square radius of gyration and the hydrodynamic radius systematically through simulation. We call polymers with nontrivial topology topological…

Soft Condensed Matter · Physics 2016-11-23 Erica Uehara , Tetsuo Deguchi

We consider the force on the end of a polymer chain being pulled through a network at velocity $v$, using computer simulations. We develop algorithms for measuring the force on the end of the chain using lattice models of polymers. Our…

Condensed Matter · Physics 2009-10-22 J. M. Deutsch , Hyoungsoo Yoon

Using molecular dynamics simulations we examine the dynamics of a family of model polymers with varying chain length and torsional potential barriers. We focus on features of the dynamics of polymers that are seen experimentally but absent…

Soft Condensed Matter · Physics 2019-06-11 Daniel Fragiadakis , C. Michael Roland

A convenient measure of a map or flow's chaotic action is the topological entropy. In many cases, the entropy has a homological origin: it is forced by the topology of the space. For example, in simple toral maps, the topological entropy is…

Dynamical Systems · Mathematics 2013-05-28 Sarah Tumasz , Jean-Luc Thiffeault

When two macromolecules come very near in a fluid, the surrounding molecules, having finite volume, are less likely to get in between. This leads to a pressure difference manifesting as an entropic attraction, called depletion force. Here…

Soft Condensed Matter · Physics 2020-02-26 Nathaniel Rupprecht , Dervis Can Vural

Topological surgery occurs in natural phenomena where two points are selected and attracting or repelling forces are applied. The two points are connected via an invisible `thread'. In order to model topologically such phenomena we…

Geometric Topology · Mathematics 2018-09-24 Sofia Lambropoulou , Stathis Antoniou , Nikola Samardzija

By means of sophisticated Monte Carlo methods, we investigate the conformational phase diagram of a simple model for flexible polymers with explicit thickness. The thickness constraint, which is introduced geometrically via the global…

Soft Condensed Matter · Physics 2009-02-06 Thomas Vogel , Thomas Neuhaus , Michael Bachmann , Wolfhard Janke

Extensive molecular simulations are applied to characterize the equilibrium dynamics, entanglement topology, and nonlinear extensional rheology of symmetric ring-linear polymer blends with systematically varied ring fraction $\phi_R$.…

Soft Condensed Matter · Physics 2021-12-15 Thomas C. O'Connor , Ting Ge , Gary S. Grest

The longitudinal response of single semiflexible polymers to sudden changes in externally applied forces is known to be controlled by the propagation and relaxation of backbone tension. Under many experimental circumstances, realized, e.g.,…

Soft Condensed Matter · Physics 2011-02-25 Florian Thüroff , Benedikt Obermayer , Erwin Frey