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In the \emph{trace reconstruction problem}, an unknown source string $x \in \{0,1\}^n$ is sent through a probabilistic \emph{deletion channel} which independently deletes each bit with probability $\delta$ and concatenates the surviving…

Data Structures and Algorithms · Computer Science 2020-08-31 Xi Chen , Anindya De , Chin Ho Lee , Rocco A. Servedio , Sandip Sinha

The general trace reconstruction problem seeks to recover an original sequence from its noisy copies independently corrupted by deletions, insertions, and substitutions. This problem arises in applications such as DNA data storage, a…

Machine Learning · Computer Science 2025-07-18 Franziska Weindel , Michael Girsch , Reinhard Heckel

In the usual trace reconstruction problem, the goal is to exactly reconstruct an unknown string of length $n$ after it passes through a deletion channel many times independently, producing a set of traces (i.e., random subsequences of the…

Data Structures and Algorithms · Computer Science 2020-12-17 Sami Davies , Miklos Z. Racz , Cyrus Rashtchian , Benjamin G. Schiffer

This paper studies the problem of reconstructing a word given several of its noisy copies. This setup is motivated by several applications, among them is reconstructing strands in DNA-based storage systems. Under this paradigm, a word is…

Information Theory · Computer Science 2020-01-17 Omer Sabary , Eitan Yaakobi , Alexander Yucovich

Reconstruction codes are generalizations of error-correcting codes that can correct errors by a given number of noisy reads. The study of such codes was initiated by Levenshtein in 2001 and developed recently due to applications in modern…

Information Theory · Computer Science 2023-02-21 Zuo Ye , Xin Liu , Xiande Zhang , Gennian Ge

We consider the problem of storing and retrieving information from synthetic DNA media. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on their collection of substrings…

Information Theory · Computer Science 2015-02-03 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

We study the problem of learning a node-labeled tree given independent traces from an appropriately defined deletion channel. This problem, tree trace reconstruction, generalizes string trace reconstruction, which corresponds to the tree…

Computational Complexity · Computer Science 2020-09-22 Sami Davies , Miklos Z. Racz , Cyrus Rashtchian

The DNA storage channel is considered, in which a codeword is comprised of $M$ unordered DNA molecules. At reading time, $N$ molecules are sampled with replacement, and then each molecule is sequenced. A coded-index concatenated-coding…

Information Theory · Computer Science 2022-05-23 Nir Weinberger

Encoding data as a set of unordered strings is receiving great attention as it captures one of the basic features of DNA storage systems. However, the challenge of constructing optimal redundancy codes for this channel remained elusive. In…

Information Theory · Computer Science 2023-08-16 Jin Sima , Netanel Raviv , Jehoshua Bruck

In the trace reconstruction problem, one attempts to reconstruct a fixed but unknown string $x$ of length $n$ from a given number of traces $\tilde{x}$ drawn iid from the application of a noisy process (such as the deletion channel) to $x$.…

Data Structures and Algorithms · Computer Science 2024-10-17 Ittai Rubinstein

Decoding sequences that stem from multiple transmissions of a codeword over an insertion, deletion, and substitution channel is a critical component of efficient deoxyribonucleic acid (DNA) data storage systems. In this paper, we consider a…

Information Theory · Computer Science 2020-10-30 Andreas Lenz , Issam Maarouf , Lorenz Welter , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

We study the trace reconstruction problem for spider graphs. Let $n$ be the number of nodes of a spider and $d$ be the length of each leg, and suppose that we are given independent traces of the spider from a deletion channel in which each…

Data Structures and Algorithms · Computer Science 2026-05-06 Alec Sun , William Yue

Consider two or more strings $\mathbf{x}^1,\mathbf{x}^2,\ldots,$ that are concatenated to form $\mathbf{x}=\langle \mathbf{x}^1,\mathbf{x}^2,\ldots \rangle$. Suppose that up to $\delta$ deletions occur in each of the concatenated strings.…

Information Theory · Computer Science 2023-04-20 Serge Kas Hanna

The goal of the trace reconstruction problem is to recover a string $x\in\{0,1\}^n$ given many independent {\em traces} of $x$, where a trace is a subsequence obtained from deleting bits of $x$ independently with some given probability…

Information Theory · Computer Science 2024-01-30 Kuan Cheng , Elena Grigorescu , Xin Li , Madhu Sudan , Minshen Zhu

A \emph{trace} of a sequence is generated by deleting each bit of the sequence independently with a fixed probability. The well-studied \emph{trace reconstruction} problem asks how many traces are required to reconstruct an unknown binary…

Combinatorics · Mathematics 2026-03-11 Wenjie Zhong , Xiande Zhang

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

In the trace reconstruction problem, one seeks to reconstruct a binary string $s$ from a collection of traces, each of which is obtained by passing $s$ through a deletion channel. It is known that $\exp(\tilde O(n^{1/5}))$ traces suffice to…

Information Theory · Computer Science 2022-10-21 Kayvon Mazooji , Ilan Shomorony

This paper studies the problem of encoding messages into sequences which can be uniquely recovered from some noisy observations about their substrings. The observed reads comprise consecutive substrings with some given minimum overlap. This…

Information Theory · Computer Science 2023-12-11 Hengjia Wei , Moshe Schwartz , Gennian Ge

In the beautifully simple-to-state problem of trace reconstruction, the goal is to reconstruct an unknown binary string $x$ given random "traces" of $x$ where each trace is generated by deleting each coordinate of $x$ independently with…

Data Structures and Algorithms · Computer Science 2021-03-16 Akshay Krishnamurthy , Arya Mazumdar , Andrew McGregor , Soumyabrata Pal

The sequence reconstruction problem involves a model where a sequence is transmitted over several identical channels. This model investigates the minimum number of channels required for the unique reconstruction of the transmitted sequence.…

Information Theory · Computer Science 2025-04-30 Zhaojun Lan , Yubo Sun , Wenjun Yu , Gennian Ge