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2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time-consuming, motivating the reconstruction of the velocity field from undersampled…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Pablo Arratia , Martin J. Graves , Mary McLean , Carolin Pirkl , Carola-Bibiane Schönlieb , Timo Schirmer , Florian Wiesinger , Matthias J. Ehrhardt

Detection of phase variations across optically transparent samples is often a difficult task. We propose and demonstrate a compact, lightweight and low cost quantitative phase contrast imager. Light diffracted from a pinhole is incident on…

Linear phase-contrast scanning transmission electron microscopy (STEM) techniques compatible with high-throughput 4D-STEM acquisition are widely used to enhance phase contrast in weakly scattering and beam-sensitive materials. In these…

Phase space tomography estimates correlation functions entirely from snapshots in the evolution of the wave function along a time or space variable. In contrast, traditional interferometric methods require measurement of multiple two-point…

Optics · Physics 2015-06-16 Lei Tian , Justin Lee , Se Baek Oh , George Barbastathis

Flow cytometry (FCM) is the standard multi-parameter assay for measuring single cell phenotype and functionality. It is commonly used for quantifying the relative frequencies of cell subsets in blood and disaggregated tissues. A typical…

Applications · Statistics 2020-09-01 Shai Gorsky , Cliburn Chan , Li Ma

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

Single-cell genomics has significantly advanced our understanding of cellular behavior, catalyzing innovations in treatments and precision medicine. However, single-cell sequencing technologies are inherently destructive and can only…

Machine Learning · Statistics 2024-11-08 Dominik Klein , Théo Uscidda , Fabian Theis , Marco Cuturi

Identifying thermodynamic signatures of electronic phases, such as superconductivity, is challenging in low-dimensional materials due to strong fluctuations and low probing volume. Spectroscopic methods are often used to identify new bulk…

Superconductivity · Physics 2025-04-15 Xu Chen , Yuanjie Sun , Eugen Hruska , Vivek Dixit , Jinming Yang , Yu He , Yao Wang , Fang Liu

The contrast transfer function (CTF) is widely used to evaluate phase retrieval methods in scanning transmission electron microscopy (STEM), including center-of-mass imaging, parallax imaging, direct ptychography, and iterative…

Light-field microscopy (LFM) enables single-shot capture of multi-angular information from biological samples, supporting real-time volumetric imaging. However, traditional physics-based algorithms often suffer from limited spatial…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Qihong Zhao , Shaokang Yan , Zhimin Qiao , Jinjia Wang , Bo Xiong

3D tomographic phase retrieval under the Born approximation for discrete objects supported on a $n\times n\times n$ grid is analyzed. It is proved that $n$ projections are sufficient and necessary for unique determination by computed…

Information Theory · Computer Science 2022-07-13 Albert Fannjiang

A general framework is presented which unifies the treatment of wavelet-like, quasidistribution, and tomographic transforms. Explicit formulas relating the three types of transforms are obtained. The case of transforms associated to the…

Mathematical Physics · Physics 2009-11-07 M. A. Man'ko , V. I. Man'ko , R. Vilela Mendes

We develop a theory for the compressibility of the surface states of 3D topological insulators and propose that surface probes of the compressibility via scanning single electron transistor microscopy will be a straightforward way to access…

Mesoscale and Nanoscale Physics · Physics 2013-02-06 D. S. L. Abergel , S. Das Sarma

In two-dimensional topological phases, quasiparticle excitations can carry fractional symmetry quantum numbers. We generalize this notion of symmetry fractionalization to three-dimensional topological phases, in particular to loop…

Strongly Correlated Electrons · Physics 2015-11-12 Meng Cheng

Analysis of the imaging of some simple distributions of object phase by a phase plate of Zernike type shows that sharp transitions in the object phase are well transmitted. The low-frequency components of the complete object function are…

Instrumentation and Detectors · Physics 2013-07-26 C. J. Edgcombe

Phase contrast imaging is used to observe Bose-Einstein condensates (BECs) at finite temperature in situ. The imaging technique is used to accurately derive the absolute phase shift of a probe laser beam due to both the condensate and the…

Quantum Gases · Physics 2009-09-25 R. Meppelink , R. A. Rozendaal , S. B. Koller , J. M. Vogels , P. van der Straten

Circulating tumor cells (CTCs) are cancer cells found in the bloodstream that serve as biomarkers for early cancer detection, prognostication, and disease monitoring. However, CTC detection remains challenging due to low cell abundance and…

X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. Single-mask differential phase contrastnimaging method stands out as a simple and effective approach…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jingcheng Yuan , Mini Das

Analyser-Based Phase-Contrast imaging (ABPCI) is a phase-contrast imaging method that produces high contrast images of weakly absorbing materials. However, it is only sensitive to phase variations lying in the diffraction plane of the…

Medical Physics · Physics 2021-02-11 M. C. Chalmers , M. J. Kitchen , K. Uesugi , G. Falzon , P. Quin , K. M. Pavlov

The 3-dimensional (3D) structure of the genome is of significant importance for many cellular processes. In this paper, we study the problem of reconstructing the 3D structure of chromosomes from Hi-C data of diploid organisms, which poses…

Genomics · Quantitative Biology 2024-05-30 Diego Cifuentes , Jan Draisma , Oskar Henriksson , Annachiara Korchmaros , Kaie Kubjas