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In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Here we present a method for the simultaneous segmentation of white matter lesions and normal-appearing neuroanatomical structures from multi-contrast brain MRI scans of multiple sclerosis patients. The method integrates a novel model for…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Stefano Cerri , Oula Puonti , Dominik S. Meier , Jens Wuerfel , Mark Mühlau , Hartwig R. Siebner , Koen Van Leemput

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Longitudinal magnetic resonance imaging data is used to model trajectories of change in brain regions of interest to identify areas susceptible to atrophy in those with neurodegenerative conditions like Alzheimer's disease. Most methods for…

Applications · Statistics 2024-07-25 Robert Zielinski , Kun Meng , Ani Eloyan

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

The evaluation of white matter lesion progression is an important biomarker in the follow-up of MS patients and plays a crucial role when deciding the course of treatment. Current automated lesion segmentation algorithms are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Mattias Billast , Maria Ines Meyer , Diana M. Sima , David Robben

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated segmentation and quantification is desirable but existing…

Automated brain tissue segmentation into white matter (WM), gray matter (GM), and cerebro-spinal fluid (CSF) from magnetic resonance images (MRI) is helpful in the diagnosis of neuro-disorders such as epilepsy, Alzheimer's, multiple…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Pulkit Kumar , Pravin Nagar , Chetan Arora , Anubha Gupta

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Automatic and reliable quantitative tools for MR brain image analysis are a very valuable resources for both clinical and research environments. In the last years, this field has experienced many advances with successful techniques based on…

Accurate segmentation of brain tissues such as gray matter and white matter from magnetic resonance imaging is essential for studying brain anatomy, diagnosing neurological disorders, and monitoring disease progression. Traditional methods,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Chang Sun , Rui Shi , Tsukasa Koike , Tetsuro Sekine , Akio Morita , Tetsuya Sakai

Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 Darwin Castillo , Vasudevan Lakshminarayanan , Maria J. Rodriguez-Alvarez
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