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We develop a novel parallel decomposition strategy for unweighted, undirected graphs, based on growing disjoint connected clusters from batches of centers progressively selected from yet uncovered nodes. With respect to similar previous…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-02-09 Matteo Ceccarello , Andrea Pietracaprina , Geppino Pucci , Eli Upfal

Memory-based Temporal Graph Neural Networks are powerful tools in dynamic graph representation learning and have demonstrated superior performance in many real-world applications. However, their node memory favors smaller batch sizes to…

Machine Learning · Computer Science 2023-07-18 Hongkuan Zhou , Da Zheng , Xiang Song , George Karypis , Viktor Prasanna

This paper is motivated by a regression analysis of electroencephalography (EEG) neuroimaging data with high-dimensional correlated responses with multi-level nested correlations. We develop a divide-and-conquer procedure implemented in a…

Methodology · Statistics 2020-05-29 Emily C. Hector , Peter X. -K. Song

Distributed systems can be found in various applications, e.g., in robotics or autonomous driving, to achieve higher flexibility and robustness. Thereby, data flow centric applications such as Deep Neural Network (DNN) inference benefit…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-14 Fabian Kreß , El Mahdi El Annabi , Tim Hotfilter , Julian Hoefer , Tanja Harbaum , Juergen Becker

Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a growing need for better assembly and assembly validation methods. One…

Genomics · Quantitative Biology 2022-10-17 Przemysław Stawczyk , Robert Nowak

Graph neural networks (GNNs) have gained significant interest for applications such as citation network analysis and drug discovery due to their ability to apply machine learning techniques on graph-structured data. GNNs typically employ a…

Hardware Architecture · Computer Science 2026-05-28 Siddhartha Raman Sundara Raman , Lizy John , Jaydeep P. Kulkarni

Sparse data structures are commonly used in neural networks to reduce the memory footprint. These data structures are compact but cause irregularities such as random memory accesses, which prevent efficient use of the memory hierarchy. GPUs…

Programming Languages · Computer Science 2025-06-19 Hossein Albakri , Kazem Cheshmi

Graph Neural Networks (GNN) exhibit superior performance in graph representation learning, but their inference cost can be high, due to an aggregation operation that can require a memory fetch for a very large number of nodes. This…

Machine Learning · Computer Science 2025-03-18 Yaochen Hu , Mai Zeng , Ge Zhang , Pavel Rumiantsev , Liheng Ma , Yingxue Zhang , Mark Coates

In the field of computational molecule generation, an essential task in the discovery of new chemical compounds, fragment-based deep generative models are a leading approach, consistently achieving state-of-the-art results in molecular…

Biomolecules · Quantitative Biology 2024-05-10 Sergei Voloboev

Long-distance quantum communication via entanglement distribution is of great importance for the quantum internet. However, scaling up to such long distances has proved challenging due to the loss of photons, which grows exponentially with…

Scaffolding is an important subproblem in "de novo" genome assembly in which mate pair data are used to construct a linear sequence of contigs separated by gaps. Here we present SLIQ, a set of simple linear inequalities derived from the…

Genomics · Quantitative Biology 2011-11-10 Rajat S. Roy , Kevin C. Chen , Anirvan M. Sengupta , Alexander Schliep

This paper considers the problem of distributed optimization over time-varying graphs. For the case of undirected graphs, we introduce a distributed algorithm, referred to as DIGing, based on a combination of a distributed inexact gradient…

Optimization and Control · Mathematics 2017-03-21 Angelia Nedich , Alex Olshevsky , Wei Shi

Computing high quality node separators in large graphs is necessary for a variety of applications, ranging from divide-and-conquer algorithms to VLSI design. In this work, we present a novel distributed evolutionary algorithm tackling the…

Neural and Evolutionary Computing · Computer Science 2017-02-07 Peter Sanders , Christian Schulz , Darren Strash , Robert Williger

The rapid development of parallel and distributed computing paradigms has brought about great revolution in computing. Thanks to the intrinsic parallelism of evolutionary computation (EC), it is natural to implement EC on parallel and…

Neural and Evolutionary Computing · Computer Science 2023-04-13 Wei-Neng Chen , Feng-Feng Wei , Tian-Fang Zhao , Kay Chen Tan , Jun Zhang

With the increasing affordability and accessibility of genome sequencing data, de novo genome assembly is an important first step to a wide variety of downstream studies and analyses. Therefore, bioinformatics tools that enable the…

Genomics · Quantitative Biology 2023-06-09 Lauren Coombe , René L. Warren , Johnathan Wong , Vladimir Nikolic , Inanc Birol

The Jaccard similarity index is an important measure of the overlap of two sets, widely used in machine learning, computational genomics, information retrieval, and many other areas. We design and implement SimilarityAtScale, the first…

Computational Engineering, Finance, and Science · Computer Science 2020-11-12 Maciej Besta , Raghavendra Kanakagiri , Harun Mustafa , Mikhail Karasikov , Gunnar Rätsch , Torsten Hoefler , Edgar Solomonik

Affordable, high-quality whole-genome assemblies have made it possible to construct rich pangenomes that capture haplotype diversity across many species. As these datasets grow, they motivate the development of specialized techniques…

Genomics · Quantitative Biology 2025-12-19 Gorkem Kadir Solun , Ugur Dogrusoz

DNA-based storage offers unprecedented density and durability, but its scalability is fundamentally limited by the efficiency of parallel strand synthesis. Existing methods either allow unconstrained nucleotide additions to individual…

Information Theory · Computer Science 2025-10-27 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

We present a novel distributed algorithm for counting all four-node induced subgraphs in a big graph. These counts, called the $4$-profile, describe a graph's connectivity properties and have found several uses ranging from bioinformatics…

Social and Information Networks · Computer Science 2016-04-05 Ethan R. Elenberg , Karthikeyan Shanmugam , Michael Borokhovich , Alexandros G. Dimakis

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead