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We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

Machine Learning · Computer Science 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Schizophrenia is a severe yet treatable mental disorder, it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms, therefore there is a need for…

Human-Computer Interaction · Computer Science 2023-10-26 Niki Maria Foteinopoulou , Ioannis Patras

Electroencephalography produces high-dimensional, stochastic data from which it might be challenging to extract high-level knowledge about the phenomena of interest. We address this challenge by applying the framework of variational…

Machine Learning · Computer Science 2022-08-18 Maksim Zhdanov , Saskia Steinmann , Nico Hoffmann

Schizophrenia (SZ) is a severe brain disorder marked by diverse cognitive impairments, abnormalities in brain structure, function, and genetic factors. Its complex symptoms and overlap with other psychiatric conditions challenge traditional…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince D. Calhoun , Dong Hye Ye

Structural alterations have been thoroughly investigated in the brain during the early onset of schizophrenia (SCZ) with the development of neuroimaging methods. The objective of the paper is an efficient classification of SCZ in 2…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 P Supriya Patro , Tripti Goel , S A VaraPrasad , M Tanveer , R Murugan

In spite of years of research, the mechanisms that underlie the development of schizophrenia, as well as its relapse, symptomatology, and treatment, continue to be a mystery. The absence of appropriate analytic tools to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Vigneshwaran Shankaran , Bhaskaran V

Speech-based assessment of the schizophrenia spectrum has been widely researched over in the recent past. In this study, we develop a deep learning framework to estimate schizophrenia severity scores from speech using a feature fusion…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-21 Gowtham Premananth , Carol Espy-Wilson

Electroencephalography signals (EEGs) contain rich multi-scale information crucial for understanding brain states, with potential applications in diagnosing and advancing the drug development landscape. However, extracting meaningful…

Machine Learning · Computer Science 2025-09-26 D. Darankoum , C. Habermacher , J. Volle , S. Grudinin

Epilepsy is one of the most common neurological disorders. This disease requires reliable and efficient seizure detection methods. Electroencephalography (EEG) is the gold standard for seizure monitoring, but its manual analysis is a…

Signal Processing · Electrical Eng. & Systems 2025-12-17 Annika Stiehl , Nicolas Weeger , Christian Uhl , Dominic Bechtold , Nicole Ille , Stefan Geißelsöder

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and…

Signal Processing · Electrical Eng. & Systems 2019-06-07 Xinghua Yao , Qiang Cheng , Guo-Qiang Zhang

EEG is a non-invasive technique for recording brain bioelectric activity, which has potential applications in various fields such as human-computer interaction and neuroscience. However, there are many difficulties in analyzing EEG data,…

Signal Processing · Electrical Eng. & Systems 2018-01-18 Yumeng Ye , Haichun Liu , TianHong Zhang , Changchun Pan , Genke Yang , JiJun Wang , Robert C. Qiu

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

Human-Computer Interaction · Computer Science 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

The problem of detecting the presence of Social Anxiety Disorder (SAD) using Electroencephalography (EEG) for classification has seen limited study and is addressed with a new approach that seeks to exploit the knowledge of EEG sensor…

Multimodal schizophrenia assessment systems have gained traction over the last few years. This work introduces a schizophrenia assessment system to discern between prominent symptom classes of schizophrenia and predict an overall…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-19 Gowtham Premananth , Carol Espy-Wilson

The need for high-quality automated seizure detection algorithms based on electroencephalography (EEG) becomes ever more pressing with the increasing use of ambulatory and long-term EEG monitoring. Heterogeneity in validation methods of…

Machine learning models have been successfully employed in the diagnosis of Schizophrenia disease. The impact of classification models and the feature selection techniques on the diagnosis of Schizophrenia have not been evaluated. Here, we…

Machine Learning · Computer Science 2022-07-05 M. Tanveer , Jatin Jangir , M. A. Ganaie , Iman Beheshti , M. Tabish , Nikunj Chhabra

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang