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The goal of most materials discovery is to discover materials that are superior to those currently known. Fundamentally, this is close to extrapolation, which is a weak point for most machine learning models that learn the probability…

Biomolecules · Quantitative Biology 2024-05-08 Hyunseung Kim , Haeyeon Choi , Dongju Kang , Won Bo Lee , Jonggeol Na

Supervised deep learning is most commonly applied to difficult problems defined on large and often extensively curated datasets. Here we demonstrate the ability of deep representation learning to address problems of classification and…

Machine Learning · Computer Science 2022-11-30 Benjamin L. Badger

Embedding is a common technique for analyzing multi-dimensional data. However, the embedding projection cannot always form significant and interpretable visual structures that foreshadow underlying data patterns. We propose an approach that…

Human-Computer Interaction · Computer Science 2022-09-26 Jie Li , Chun-qi Zhou

For a given metric measure space $(X,d,\mu)$ we consider finite samples of points, calculate the matrix of distances between them and then reconstruct the points in some finite-dimensional space using the multidimensional scaling (MDS)…

Metric Geometry · Mathematics 2022-08-02 Alexey Kroshnin , Eugene Stepanov , Dario Trevisan

For over three decades, scanning probe microscopy (SPM) has been a key method for exploring material structures and functionalities at nanometer and often atomic scales in ambient, liquid, and vacuum environments. Historically, SPM…

In this report, we introduce Piccolo2, an embedding model that surpasses other models in the comprehensive evaluation over 6 tasks on CMTEB benchmark, setting a new state-of-the-art. Piccolo2 primarily leverages an efficient multi-task…

Computation and Language · Computer Science 2024-05-14 Junqin Huang , Zhongjie Hu , Zihao Jing , Mengya Gao , Yichao Wu

We present a new technique for visualizing high-dimensional data called cluster MDS (cl-MDS), which addresses a common difficulty of dimensionality reduction methods: preserving both local and global structures of the original sample in a…

Graphics · Computer Science 2024-05-27 Patricia Hernández-León , Miguel A. Caro

Statistical shape modeling is the computational process of discovering significant shape parameters from segmented anatomies captured by medical images (such as MRI and CT scans), which can fully describe subject-specific anatomy in the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Krithika Iyer , Shireen Elhabian

Mass Spectrometry (MS) is a largely used analytical technique in biology with applications such as the determination of molecule masses or the elucidation of structural data. Fourier Transform Ion Cyclotron Resonance MS is one…

Chemical Physics · Physics 2019-06-17 Laura Duciel , Afef Cherni , Marc-André Delsuc

Compound identification from tandem mass spectrometry (MS/MS) data is a critical step in the analysis of complex mixtures. Typical solutions for the MS/MS spectrum to compound (MS2C) problem involve comparing the unknown spectrum against a…

Machine Learning · Computer Science 2025-08-28 Adamo Young , Fei Wang , David S Wishart , Bo Wang , Russell Greiner , Hannes Röst

Embeddings are a basic initial feature extraction step in many machine learning models, particularly in natural language processing. An embedding attempts to map data tokens to a low-dimensional space where similar tokens are mapped to…

Machine Learning · Computer Science 2025-04-10 Golara Ahmadi Azar , Melika Emami , Alyson Fletcher , Sundeep Rangan

Few-shot deep learning is a topical challenge area for scaling visual recognition to open ended growth of unseen new classes with limited labeled examples. A promising approach is based on metric learning, which trains a deep embedding to…

Computer Vision and Pattern Recognition · Computer Science 2020-04-29 Xueting Zhang , Yuting Qiang , Flood Sung , Yongxin Yang , Timothy M. Hospedales

Machine learning over-fitting caused by data scarcity greatly limits the application of machine learning for molecules. Due to manufacturing processes difference, big data is not always rendered available through computational chemistry…

Machine Learning · Computer Science 2020-11-20 Ziyang Zhang , Yingtao Luo

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

The recent rapid growth of the dimension of many datasets means that many approaches to dimension reduction (DR) have gained significant attention. High-performance DR algorithms are required to make data analysis feasible for big and fast…

Machine Learning · Computer Science 2021-11-09 Samudra Herath , Matthew Roughan , Gary Glonek

Nanomechanical spectroscopy (NMS) is a recently developed approach to determine optical absorption spectra of nanoscale materials via mechanical measurements. It is based on measuring changes in the resonance frequency of a membrane…

Synthesis of advanced inorganic materials with minimum number of trials is of paramount importance towards the acceleration of inorganic materials development. The enormous complexity involved in existing multi-variable synthesis methods…

Materials Science · Physics 2020-11-02 Bijun Tang , Yuhao Lu , Jiadong Zhou , Han Wang , Prafful Golani , Manzhang Xu , Quan Xu , Cuntai Guan , Zheng Liu

Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun

A set of molecular descriptors whose length is independent of molecular size is developed for machine learning models that target thermodynamic and electronic properties of molecules. These features are evaluated by monitoring performance…