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Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective, causing delays in diagnosis. Digital pathology plays a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Marian Boktor , James E. D. Tweel , Benjamin R. Ecclestone , Jennifer Ai Ye , Paul Fieguth , Parsin Haji Reza

A major challenge in applying deep learning to medical imaging is the paucity of annotated data. This study demonstrates that synthetic colonoscopy images generated by Generative Adversarial Network (GAN) inversion can be used as training…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Mayank Golhar , Taylor L. Bobrow , Saowanee Ngamruengphong , Nicholas J. Durr

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Semantic segmentation of various tissue and nuclei types in histology images is fundamental to many downstream tasks in the area of computational pathology (CPath). In recent years, Deep Learning (DL) methods have been shown to perform well…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Raja Muhammad Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

Deep learning in medical imaging faces obstacles: limited data diversity, ethical issues, high acquisition costs, and the need for precise annotations. Bleeding detection and localization during surgery is especially challenging due to the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Niran Nataraj , Maina Sogabe , Kenji Kawashima

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially…

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Deep learning in medical imaging often requires large-scale, high-quality data or initiation with suitably pre-trained weights. However, medical datasets are limited by data availability, domain-specific knowledge, and privacy concerns, and…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Zelong Liu , Alexander Zhou , Arnold Yang , Alara Yilmaz , Maxwell Yoo , Mikey Sullivan , Catherine Zhang , James Grant , Daiqing Li , Zahi A. Fayad , Sean Huver , Timothy Deyer , Xueyan Mei

We introduce a challenging training scheme of conditional GANs, called open-set semi-supervised image generation, where the training dataset consists of two parts: (i) labeled data and (ii) unlabeled data with samples belonging to one of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Kai Katsumata , Duc Minh Vo , Hideki Nakayama

Self-supervised learning (SSL) has emerged as a powerful paradigm for medical image representation learning, particularly in settings with limited labeled data. However, existing SSL methods often rely on complex architectures,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Azad Singh , Deepak Mishra

Deep learning has significant potential for medical imaging. However, since the incident rate of each disease varies widely, the frequency of classes in a medical image dataset is imbalanced, leading to poor accuracy for such infrequent…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Tatsuki Koga , Naoki Nonaka , Jun Sakuma , Jun Seita

The success of deep learning in medical imaging is mostly achieved at the cost of a large labeled data set. Semi-supervised learning (SSL) provides a promising solution by leveraging the structure of unlabeled data to improve learning from…

Machine Learning · Computer Science 2019-07-24 Prashnna Kumar Gyawali , Zhiyuan Li , Sandesh Ghimire , Linwei Wang

Recent advancements in ophthalmology foundation models such as RetFound have demonstrated remarkable diagnostic capabilities but require massive datasets for effective pre-training, creating significant barriers for development and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Qingshan Hou , Meng Wang , Peng Cao , Zou Ke , Xiaoli Liu , Huazhu Fu , Osmar R. Zaiane

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

Semi-supervised learning (semi-SL) is a promising alternative to supervised learning for medical image analysis when obtaining good quality supervision for medical imaging is difficult. However, semi-SL assumes that the underlying…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Nikhil Cherian Kurian , Varsha S , Abhijit Patil , Shashikant Khade , Amit Sethi

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

In recent years generative models of visual data have made a great progress, and now they are able to produce images of high quality and diversity. In this work we study representations learnt by a GAN generator. First, we show that these…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Danil Galeev , Konstantin Sofiiuk , Danila Rukhovich , Mikhail Romanov , Olga Barinova , Anton Konushin

Weakly-supervised learning has become a popular technology in recent years. In this paper, we propose a novel medical image classification algorithm, called Weakly-Supervised Generative Adversarial Networks (WSGAN), which only uses a small…

Computer Vision and Pattern Recognition · Computer Science 2021-12-01 Jiawei Mao , Xuesong Yin , Yuanqi Chang , Qi Huang