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Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

The article presents an efficient image reconstruction algorithm for single scattering optical tomography (SSOT) in circular geometry of data acquisition. This novel medical imaging modality uses photons of light that scatter once in the…

Numerical Analysis · Mathematics 2016-03-08 Gaik Ambartsoumian , Souvik Roy

Precise reconstruction of unknown quantum states from measurement data, a process commonly called quantum state tomography, is a crucial component in the development of quantum information processing technologies. Many different tomography…

Quantum Physics · Physics 2022-10-28 Ingrid Strandberg

Due to the COVID-19 pandemic, there is an increasing demand for portable CT machines worldwide in order to diagnose patients in a variety of settings. This has led to a need for CT image reconstruction algorithms that can produce high…

Numerical Analysis · Mathematics 2025-12-10 Mai Phuong Pham Huynh , Manuel Santana , Ana Castillo

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Proton computed tomography (pCT) is an image modality that will improve treatment planning for patients receiving proton radiation therapy compared with the current treatment techniques, which are based on X-ray CT. Reconstruction of a pCT…

Medical Physics · Physics 2021-08-30 Micah Witt , Blake Schultze , Reinhard Schulte , Keith Schubert , Ernesto Gomez

In the past decades, Computed Tomography (CT) has established itself as one of the most important imaging techniques in medicine. Today, the applicability of CT is only limited by the deposited radiation dose, reduction of which manifests…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Martin Zach , Erich Kobler , Thomas Pock

Multi-scale 3D characterization is widely used by materials scientists to further their understanding of the relationships between microscopic structure and macroscopic function. Scientific computed tomography (CT) instruments are one of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 S. V. Venkatakrishnan , K. Aditya Mohan , Amir Koushyar Ziabari , Charles A. Bouman

Limited-angle computed tomography (CT) image reconstruction is a challenging reconstruction problem in the fields of CT. With the development of deep learning, the generative adversarial network (GAN) perform well in image restoration by…

Medical Physics · Physics 2019-03-12 Ziheng Li , Wenkun Zhang , Linyuan Wang , Ailong Cai , Ningning Liang , Bin Yan , Lei Li

The diagnostic quality of computed tomography (CT) scans is usually restricted by the induced patient dose, scan speed, and image quality. Sparse-angle tomographic scans reduce radiation exposure and accelerate data acquisition, but suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Fabian Wagner , Mareike Thies , Noah Maul , Laura Pfaff , Oliver Aust , Sabrina Pechmann , Christopher Syben , Andreas Maier

Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Ruiwen Xing , Thomas Humphries , Dong Si

Cone-beam computed tomography (CBCT) systems, with their flexibility, present a promising avenue for direct point-of-care medical imaging, particularly in critical scenarios such as acute stroke assessment. However, the integration of CBCT…

Iterative image reconstruction (IIR) algorithms in Computed Tomography (CT) are based on algorithms for solving a particular optimization problem. Design of the IIR algorithm, therefore, is aided by knowledge of the solution to the…

Medical Physics · Physics 2013-02-22 Emil Y. Sidky , Jakob S. Jørgensen , Xiaochuan Pan

With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…

Medical Physics · Physics 2023-01-25 Yuanwei He , Li Zeng , Qiong Xu , Zhe Wang , Haijun Yu , Zhaoqiang Shen , Zhaojun Yang , Rifeng Zhou

Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…

Medical Physics · Physics 2026-02-18 Gábor Bíró , Ákos Sudár , Zsófia Jólesz , Gábor Papp , Gergely Gábor Barnaföldi

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Computed Tomography (CT) is a frequently utilized imaging technology that is employed in the clinical diagnosis of many disorders. However, clinical diagnosis, data storage, and management are posed huge challenges by a huge volume of…

Image and Video Processing · Electrical Eng. & Systems 2024-05-02 Siyi Xun , Qiaoyu Li , Xiaohong Liu , Guangtao Zhai , Mingxiang Wu , Tao Tan

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

X-ray computed tomography (CT) is widely utilized in the medical, industrial, and other fields to nondestructively generate three-dimensional structural images of objects. However, CT images are often affected by various artifacts, with…

Medical Physics · Physics 2025-05-27 Yang Zou , Meili Qi , Jianhua Zhang , Difei Zhang , Shuwei Wang , Jiale Zhang , Shengkun Yao , Huaidong Jiang

Low Dose Computed Tomography suffers from a high amount of noise and/or undersampling artefacts in the reconstructed image. In the current article, a Deep Learning technique is exploited as a regularization term for the iterative…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Shabab Bazrafkan , Vincent Van Nieuwenhove , Joris Soons , Jan De Beenhouwer , Jan Sijbers