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We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Although high resolution isotropic 3D medical images are desired in clinical practice, their acquisition is not always feasible. Instead, lower resolution images are upsampled to higher resolution using conventional interpolation methods.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Jörg Sander , Bob D. de Vos , Ivana Išgum

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

In the past decades, automated high-content microscopy demonstrated its ability to deliver large quantities of image-based data powering the versatility of phenotypic drug screening and systems biology applications. However, as the sizes of…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Vaibhav Sharma , Artur Yakimovich

The initial assessment of skin lesions is typically based on dermoscopic images. As this is a difficult and time-consuming task, machine learning methods using dermoscopic images have been proposed to assist human experts. Other approaches…

Computer Vision and Pattern Recognition · Computer Science 2020-02-06 Nils Gessert , Marcel Bengs , Alexander Schlaefer

Smoke generated by surgical instruments during laparoscopic surgery can obscure the visual field, impairing surgeons' ability to perform operations accurately and safely. Thus, smoke removal task for laparoscopic images is highly desirable.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Wenhui Chang , Hongming Chen

Recently, with the significant developments in deep learning techniques, solving underdetermined inverse problems has become one of the major concerns in the medical imaging domain. Typical examples include undersampled magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-06-29 Chang Min Hyun , Seong Hyeon Baek , Mingyu Lee , Sung Min Lee , Jin Keun Seo

Contrast Enhanced Spectral Mammography (CESM) is a dual-energy mammographic imaging technique that first needs intravenously administration of an iodinated contrast medium; then, it collects both a low-energy image, comparable to standard…

Image and Video Processing · Electrical Eng. & Systems 2026-03-13 Aurora Rofena , Valerio Guarrasi , Marina Sarli , Claudia Lucia Piccolo , Matteo Sammarra , Bruno Beomonte Zobel , Paolo Soda

This paper presents a novel method of smoke removal from the laparoscopic images. Due to the heterogeneous nature of surgical smoke, a two-stage network is proposed to estimate the smoke distribution and reconstruct a clear, smoke-free…

Image and Video Processing · Electrical Eng. & Systems 2024-04-12 Ziteng Liu , Jiahua Zhu , Bainan Liu , Hao Liu , Wenpeng Gao , Yili Fu

The performance of imaging techniques has an important influence on the clinical diagnostic strategy of colorectal cancer. Linked color imaging (LCI) by laser endoscopy is a recently developed techniques, and its advantage in improving the…

Image and Video Processing · Electrical Eng. & Systems 2018-08-01 Xinran Wei , Jiyang Xie , Wenrui He , Min Min , Zhanyu Ma , Jun Guo

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

Depth estimation is a cornerstone of 3D reconstruction and plays a vital role in minimally invasive endoscopic surgeries. However, most current depth estimation networks rely on traditional convolutional neural networks, which are limited…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Bojian Li , Bo Liu , Xinning Yao , Jinghua Yue , Fugen Zhou

Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Ziling Wu , Tekin Bicer , Zhengchun Liu , Vincent De Andrade , Yunhui Zhu , Ian T. Foster

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

Segmenting polyps in colonoscopy images is essential for the early identification and diagnosis of colorectal cancer, a significant cause of worldwide cancer deaths. Prior deep learning based models such as Attention based variation, UNet…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Al Mohimanul Islam , Sadia Shakiba Bhuiyan , Mysun Mashira , Md. Rayhan Ahmed , Salekul Islam , Swakkhar Shatabda

Laparoscopic surgery has a limited field of view. Laser ablation in a laproscopic surgery causes smoke, which inevitably influences the surgeon's visibility. Therefore, it is of vital importance to remove the smoke, such that a clear…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Congcong Wang , Vivek Sharma , Yu Fan , Faouzi Alaya Cheikh , Azeddine Beghdadi , Ole Jacob Elle , Rainer Stiefelhagen

Deep learning techniques hold promise to develop dense topography reconstruction and pose estimation methods for endoscopic videos. However, currently available datasets do not support effective quantitative benchmarking. In this paper, we…

Optical colonoscopy (OC), the most prevalent colon cancer screening tool, has a high miss rate due to a number of factors, including the geometry of the colon (haustral fold and sharp bends occlusions), endoscopist inexperience or fatigue,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Shawn Mathew , Saad Nadeem , Arie Kaufman
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