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Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…

Neurons and Cognition · Quantitative Biology 2024-01-31 Fuad Noman , Chee-Ming Ting , Hakmook Kang , Raphael C. -W. Phan , Brian D. Boyd , Warren D. Taylor , Hernando Ombao

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

Neurons and Cognition · Quantitative Biology 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by atypical functional brain connectivity and subtle structural alterations. rs-fMRI has been widely used to identify disruptions in large-scale brain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ansar Rahman , Hassan Shojaee-Mend , Sepideh Hatamikia

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

Machine Learning · Statistics 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Small sample sizes in neuroimaging in general, and in structural connectome (SC) studies in particular limit the development of reliable biomarkers for neurological and psychiatric disorders - such as Alzheimer's disease and schizophrenia -…

Structural connectomes are detailed graphs that map how different brain regions are physically connected, offering critical insight into aging, cognition, and neurodegenerative diseases. However, these connectomes are high-dimensional and…

Under the framework of network-based neurodegeneration, brain functional connectome (FC)-based Graph Neural Networks (GNN) have emerged as a valuable tool for the diagnosis and prognosis of neurodegenerative diseases such as Alzheimer's…

Neurons and Cognition · Quantitative Biology 2023-07-14 Zijian Dong , Yilei Wu , Yu Xiao , Joanna Su Xian Chong , Yueming Jin , Juan Helen Zhou

Predicting disease states from functional brain connectivity is critical for the early diagnosis of severe neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease. Existing studies commonly employ Graph Neural…

Machine Learning · Computer Science 2025-04-22 David Yang , Mostafa Abdelmegeed , John Modl , Minjeong Kim

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

Machine Learning · Statistics 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson

Graph Transformers have recently been successful in various graph representation learning tasks, providing a number of advantages over message-passing Graph Neural Networks. Utilizing Graph Transformers for learning the representation of…

Neurons and Cognition · Quantitative Biology 2023-12-27 Byung-Hoon Kim , Jungwon Choi , EungGu Yun , Kyungsang Kim , Xiang Li , Juho Lee

Brain networks have received considerable attention given the critical significance for understanding human brain organization, for investigating neurological disorders and for clinical diagnostic applications. Structural brain network…

Machine Learning · Computer Science 2019-11-12 Jiahao Liu , Guixiang Ma , Fei Jiang , Chun-Ta Lu , Philip S. Yu , Ann B. Ragin

Brain network analysis is a useful approach to studying human brain disorders because it can distinguish patients from healthy people by detecting abnormal connections. Due to the complementary information from multiple modal neuroimages,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Qiankun Zuo , Yanfei Zhu , Libin Lu , Zhi Yang , Yuhui Li , Ning Zhang

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

This paper presents a novel graph-based kernel learning approach for connectome analysis. Specifically, we demonstrate how to leverage the naturally available structure within the graph representation to encode prior knowledge in the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jun Yu , Zhaoming Kong , Aditya Kendre , Hao Peng , Carl Yang , Lichao Sun , Alex Leow , Lifang He

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

Neurons and Cognition · Quantitative Biology 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

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