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Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…
One of the main issues of the current tractography methods is their high false-positive rate. Tractogram filtering is an option to remove false-positive streamlines from tractography data in a post-processing step. In this paper, we train a…
Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive…
Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…
Our understanding of the human connectome is fundamentally limited by the resolution of diffusion MR images. Reconstructing a connectome's constituent neural pathways with tractography requires following a continuous field of fiber…
A fundamental challenge in neuroscience is to decode mental states from brain activity. While functional magnetic resonance imaging (fMRI) offers a non-invasive approach to capture brain-wide neural dynamics with high spatial precision,…
Many existing methods that use functional magnetic resonance imaging (fMRI) classify brain disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), often overlook the integration of spatial and…
Network analysis of human brain connectivity indicates that individual differences in cognitive abilities arise from neurobiological mechanisms inherent in structural and functional brain networks. Existing studies routinely treat…
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by disruptions in brain connectivity. Functional MRI (fMRI) offers a non-invasive window into large-scale neural dynamics by measuring…
In the last years in-vivo tractography has assumed an important role in neurosciences, for both research and clinical applications such as non-invasive investigation of brain connectivity and presurgical planning in neurosurgery. In more…
Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…
White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white…
The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…
Parcellation of white matter tractography provides anatomical features for disease prediction, anatomical tract segmentation, surgical brain mapping, and non-imaging phenotype classifications. However, parcellation does not always reach…
We propose a geometric deep-learning-based framework, TractGeoNet, for performing regression using diffusion magnetic resonance imaging (dMRI) tractography and associated pointwise tissue microstructure measurements. By employing a point…
Transformer-based architectures have advanced medical image analysis by effectively modeling long-range dependencies, yet they often struggle in 3D settings due to substantial memory overhead and insufficient capture of fine-grained local…
Recent progress in diffusion MRI and tractography algorithms as well as the launch of the Human Connectome Project (HCP) have provided brain research with an abundance of structural connectivity data. In this work, we describe and evaluate…
Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…
Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…
Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…