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Rare diseases have extremely low-data regimes, unlike common diseases with large amount of available labeled data. Hence, to train a neural network to classify rare diseases with a few per-class data samples is very challenging, and so far,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Xiaomeng Li , Lequan Yu , Yueming Jin , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Active learning for imbalanced classification tasks is challenging as the minority classes naturally occur rarely. Gathering a large pool of unlabelled data is thus essential to capture minority instances. Standard pool-based active…

Machine Learning · Computer Science 2024-10-17 Pietro Lesci , Andreas Vlachos

Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment. These learning…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Iain Carmichael , Andrew H. Song , Richard J. Chen , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Machine Learning (ML) is widely used to automatically extract meaningful information from Electronic Health Records (EHR) to support operational, clinical, and financial decision-making. However, ML models require a large number of…

Machine Learning · Computer Science 2021-04-14 Martha Dais Ferreira , Michal Malyska , Nicola Sahar , Riccardo Miotto , Fernando Paulovich , Evangelos Milios

Training deep learning models on medical datasets that perform well for all classes is a challenging task. It is often the case that a suboptimal performance is obtained on some classes due to the natural class imbalance issue that comes…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Atharv Savarkar , Venkat Iyer , Lakshman Tamil , Ganesh Ramakrishnan , Rishabh Iyer

Active learning (AL) is a prominent technique for reducing the annotation effort required for training machine learning models. Deep learning offers a solution for several essential obstacles to deploying AL in practice but introduces many…

Computation and Language · Computer Science 2022-05-10 Akim Tsvigun , Artem Shelmanov , Gleb Kuzmin , Leonid Sanochkin , Daniil Larionov , Gleb Gusev , Manvel Avetisian , Leonid Zhukov

Classification and localization are two pillars of visual object detectors. However, in CNN-based detectors, these two modules are usually optimized under a fixed set of candidate (or anchor) bounding boxes. This configuration significantly…

Computer Vision and Pattern Recognition · Computer Science 2019-12-06 Wei Ke , Tianliang Zhang , Zeyi Huang , Qixiang Ye , Jianzhuang Liu , Dong Huang

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Unsupervised anomaly detection using deep learning has garnered significant research attention due to its broad applicability, particularly in medical imaging where labeled anomalous data are scarce. While earlier approaches leverage…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Chunlei Li , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Multiple-instance learning (MIL) is a paradigm of machine learning that aims to classify a set (bag) of objects (instances), assigning labels only to the bags. This problem is often addressed by selecting an instance to represent each bag,…

Human-Computer Interaction · Computer Science 2021-12-22 Sonia Castelo , Moacir Ponti , Rosane Minghim

Understanding and identifying different types of single molecules' diffusion that occur in a broad range of systems (including living matter) is extremely important, as it can provide information on the physical and chemical characteristics…

Quantitative Methods · Quantitative Biology 2023-03-07 Patrycja Kowalek , Hanna Loch-Olszewska , Łukasz Łaszczuk , Jarosław Opała , Janusz Szwabiński

Weakly-supervised audio-visual violence detection aims to distinguish snippets containing multimodal violence events with video-level labels. Many prior works perform audio-visual integration and interaction in an early or intermediate…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Jiashuo Yu , Jinyu Liu , Ying Cheng , Rui Feng , Yuejie Zhang

Accurate classification of Acute Myeloid Leukemia (AML) subtypes is crucial for clinical decision-making and patient care. In this study, we investigate the potential presence of age and sex bias in AML subtype classification using Multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Ario Sadafi , Matthias Hehr , Nassir Navab , Carsten Marr

In many real-world tasks, the concerned objects can be represented as a multi-instance bag associated with a candidate label set, which consists of one ground-truth label and several false positive labels. Multi-instance partial-label…

Machine Learning · Computer Science 2023-09-29 Wei Tang , Weijia Zhang , Min-Ling Zhang

Weakly Supervised Video Anomaly Detection (WSVAD) is challenging because the binary anomaly label is only given on the video level, but the output requires snippet-level predictions. So, Multiple Instance Learning (MIL) is prevailing in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Hui Lv , Zhongqi Yue , Qianru Sun , Bin Luo , Zhen Cui , Hanwang Zhang

Automated analysis of tissue sections allows a better understanding of disease biology and may reveal biomarkers that could guide prognosis or treatment selection. In digital pathology, less abundant cell types can be of biological…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Yeman Brhane Hagos , Catherine SY Lecat , Dominic Patel , Lydia Lee , Thien-An Tran , Manuel Rodriguez- Justo , Kwee Yong , Yinyin Yuan

Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies…

In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…

Machine Learning · Computer Science 2022-11-14 Daiki Suehiro , Eiji Takimoto

Multiple-instance learning is a subset of weakly supervised learning where labels are applied to sets of instances rather than the instances themselves. Under the standard assumption, a set is positive only there is if at least one instance…

Machine Learning · Computer Science 2021-05-05 Daniel Grahn

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is…