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Reliable confidence measures of metrics derived from medical imaging reconstruction pipelines would improve the standard of decision-making in many clinical workflows. Conformal Prediction (CP) provides a robust framework for producing…

What advantage do \emph{sequential} procedures provide over batch algorithms for testing properties of unknown distributions? Focusing on the problem of testing whether two distributions $\mathcal{D}_1$ and $\mathcal{D}_2$ on $\{1,\dots,…

Data Structures and Algorithms · Computer Science 2022-05-13 Omar Fawzi , Nicolas Flammarion , Aurélien Garivier , Aadil Oufkir

We present a method for computing optimal fixed-width confidence intervals for a single, bounded parameter, extending a method for the binomial due to Asparaouhov and Lorden, who called it the Push algorithm. The method produces the…

Methodology · Statistics 2025-11-18 Jay Bartroff , Asmit Chakraborty

Consider a statistical problem where a set of parameters are of interest to a researcher. Then multiple confidence intervals can be constructed to infer the set of parameters simultaneously. The constructed multiple confidence intervals are…

Methodology · Statistics 2019-12-10 Taeho Kim , Edsel A. Pena

Certifiable, adaptive uncertainty estimates for unknown quantities are an essential ingredient of sequential decision-making algorithms. Standard approaches rely on problem-dependent concentration results and are limited to a specific…

Machine Learning · Computer Science 2023-11-09 Nicolas Emmenegger , Mojmír Mutný , Andreas Krause

We treat success runs of independent identically distributed Bernoulli trials (with success parameter $p$) distributed according to the Type II binomial distribution of order $k$. However, the success runs are separated by a gap $g\ge1$ (a…

Probability · Mathematics 2025-12-02 S. J. Dilworth , S. R. Mane

Small sample sizes in clinical studies arises from factors such as reduced costs, limited subject availability, and the rarity of studied conditions. This creates challenges for accurately calculating confidence intervals (CIs) using the…

Methodology · Statistics 2025-11-11 Mulan Wu , Mengyu Xu , Dongyun Kim

In econometrics, many parameters of interest can be written as ratios of expectations. The main approach to construct confidence intervals for such parameters is the delta method. However, this asymptotic procedure yields intervals that may…

Statistics Theory · Mathematics 2019-04-16 Alexis Derumigny , Lucas Girard , Yannick Guyonvarch

A large class of problems in sciences and engineering can be formulated as the general problem of constructing random intervals with pre-specified coverage probabilities for the mean. Wee propose a general approach for statistical inference…

Statistics Theory · Mathematics 2013-06-11 Xinjia Chen

We study the problem of learning individualized dose intervals using observational data. There are very few previous works for policy learning with continuous treatment, and all of them focused on recommending an optimal dose rather than an…

Methodology · Statistics 2022-02-25 Guanhua Chen , Xiaomao Li , Menggang Yu

Informative interim adaptations lead to random sample sizes. The random sample size becomes a component of the sufficient statistic and estimation based solely on observed samples or on the likelihood function does not use all available…

Methodology · Statistics 2022-10-25 Sergey Tarima , Nancy Flournoy

Bayesian inference allows us to define a posterior distribution over the weights of a generic neural network (NN). Exact posteriors are usually intractable, in which case approximations can be employed. One such approximation - variational…

Machine Learning · Computer Science 2026-01-30 Andrew Millard , Joshua Murphy , Peter Green , Simon Maskell

Multi-level normal hierarchical models, also interpreted as mixed effects models, play an important role in developing statistical theory in multi-parameter estimation for a wide range of applications. In this article, we propose a novel…

Statistics Theory · Mathematics 2025-11-18 Aditi Sen , Masayo Y. Hirose , Partha Lahiri

Clinical trials often evaluate multiple outcome variables to form a comprehensive picture of the effects of a new treatment. The resulting multidimensional insight contributes to clinically relevant and efficient decision-making about…

Methodology · Statistics 2023-08-14 X. M. Kavelaars , J. Mulder , M. C. Kaptein

Test procedures for multiple hypotheses in a group sequential clinical trial that control the family-wise error rate are considered. Several graphical group sequential tests suggested in the literature, which are special cases of…

Methodology · Statistics 2026-05-13 Liane Kluge , Werner Brannath

We study the problem of designing consistent sequential two-sample tests in a nonparametric setting. Guided by the principle of testing by betting, we reframe this task into that of selecting a sequence of payoff functions that maximize the…

Statistics Theory · Mathematics 2025-08-26 Shubhanshu Shekhar , Aaditya Ramdas

We develop and apply two calibration procedures for checking the coverage of approximate Bayesian credible sets including intervals estimated using Monte Carlo methods. The user has an ideal prior and likelihood, but generates a credible…

Computation · Statistics 2026-05-19 Jeong Eun Lee , Geoff K. Nicholls , Robin J. Ryder

A common method to reduce the uncertainty of causal inferences from experiments is to assign treatments in fixed proportions within groups of similar units: blocking. Previous results indicate that one can expect substantial reductions in…

Methodology · Statistics 2015-08-31 Fredrik Sävje

The multivariate Fay-Herriot model is quite effective in combining information through correlations among small area survey estimates of related variables or historical survey estimates of the same variable or both. Though the literature on…

Methodology · Statistics 2020-06-29 Takumi Saegusa , Shonosuke Sugasawa , Partha Lahiri

In the analysis of survey data it is of interest to estimate and quantify uncertainty about means or totals for each of several non-overlapping subpopulations, or areas. When the sample size for a given area is small, standard confidence…

Methodology · Statistics 2018-09-26 Kyle Burris , Peter Hoff