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Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmology studies, the primary outcome is often obtained from one eye or both eyes of an individual. In…

Methodology · Statistics 2021-11-01 Kejia Wang , Chang-Xing Ma

Due to ethical and economical reasons, sequential single-arm trial designs are used for assessing the therapeutic efficacy of new treatments in phase II trials. Simon's 2-stage design and Lan-DeMets' $\alpha$-spending function method with…

Methodology · Statistics 2023-03-31 Tasuku Inao , Isao Yokota

Vertically weighted averages perform a bilateral filtering of data, in order to preserve fine details of the underlying signal, especially discontinuities such as jumps (in dimension one) or edges (in dimension two). In homogeneous regions…

Methodology · Statistics 2018-03-20 Ansgar Steland

The proposed approach extends the confidence posterior distribution to the semi-parametric empirical Bayes setting. Whereas the Bayesian posterior is defined in terms of a prior distribution conditional on the observed data, the confidence…

Methodology · Statistics 2012-05-02 David R. Bickel

Group sequential designs drive innovation in clinical, industrial, and corporate settings. Early stopping for failure in sequential designs conserves experimental resources, whereas early stopping for success accelerates access to improved…

Methodology · Statistics 2025-11-27 Luke Hagar , Shirin Golchi , Marina B. Klein

We propose a new statistical hypothesis testing framework which decides visually, using confidence intervals, whether the means of two samples are equal or if one is larger than the other. With our method, the user can at the same time…

Statistics Theory · Mathematics 2025-03-06 Timothée Mathieu

We consider the problem of constructing confidence intervals (CIs) for the population mean of $N$ values $\{x_1, \ldots, x_N\} \subset \Sigma^N$ based on a random sample of size $n$, denoted by $X^n \equiv (X_1, \ldots, X_n)$, drawn…

Statistics Theory · Mathematics 2026-03-17 Shubhanshu Shekhar , Aaditya Ramdas

We develop scalable methods for producing conformal Bayesian predictive intervals with finite sample calibration guarantees. Bayesian posterior predictive distributions, $p(y \mid x)$, characterize subjective beliefs on outcomes of…

Methodology · Statistics 2021-06-15 Edwin Fong , Chris Holmes

Confidence interval (CI) methods for stratified bilateral studies use intraclass correlation to avoid misleading results. In this article, we propose four CI methods (sample-size weighted global MLE-based Wald-type CI, complete MLE-based…

Methodology · Statistics 2023-03-27 Wanqing Tian , Chang-Xing Ma

A confidence sequence (CS) is a sequence of confidence intervals that is valid at arbitrary data-dependent stopping times. These are useful in applications like A/B testing, multi-armed bandits, off-policy evaluation, election auditing,…

Statistics Theory · Mathematics 2024-02-09 Hongjian Wang , Aaditya Ramdas

The task of monitoring for a change in the mean of a sequence of Bernoulli random variables has been widely studied. However most existing approaches make at least one of the following assumptions, which may be violated in many real-world…

Computation · Statistics 2015-05-08 Gordon J. Ross , Dimitris K. Tasoulis , Niall M. Adams

Confidence intervals (CIs) are instrumental in statistical analysis, providing a range estimate of the parameters. In modern statistics, selective inference is common, where only certain parameters are highlighted. However, this selective…

Methodology · Statistics 2025-09-17 Tzviel Frostig , Yoav Benjamini , Ruth Heller

In designing an online A/B experiment, it is crucial to select a sample size and duration that ensure the resulting confidence interval (CI) for the treatment effect is the right width to detect an effect of meaningful magnitude with…

Methodology · Statistics 2024-08-07 Harrison H. Li , Chaoyu Yu

Change point detection plays a fundamental role in many real-world applications, where the goal is to analyze and monitor the behaviour of a data stream. In this paper, we study change detection in binary streams. To this end, we use a…

Machine Learning · Computer Science 2023-01-24 Nikolaj Tatti

We first review existing sequential methods for estimating a binomial proportion. Afterward, we propose a new family of group sequential sampling schemes for estimating a binomial proportion with prescribed margin of error and confidence…

Statistics Theory · Mathematics 2013-11-05 Zhengjia Chen , Xinjia Chen

Performance uncertainty quantification is essential for reliable validation and eventual clinical translation of medical imaging artificial intelligence (AI). Confidence intervals (CIs) play a central role in this process by indicating how…

Extant "fast" algorithms for Monte Carlo confidence sets are limited to univariate shift parameters for the one-sample and two-sample problems using the sample mean as the test statistic; moreover, some do not converge reliably and most do…

Computation · Statistics 2025-02-27 Amanda K. Glazer , Philip B. Stark

Estimating the expectation of a Bernoulli random variable based on N independent trials is a classical problem in statistics, typically addressed using Binomial Proportion Confidence Intervals (BPCI). In the control systems community, many…

Machine Learning · Computer Science 2025-04-08 Rudi Coppola , Manuel Mazo

Discovery problems often require deciding whether additional sampling is needed to detect all categories whose prevalence exceeds a prespecified threshold. We study this question under a Bernoulli product (incidence) model, where categories…

Methodology · Statistics 2026-01-29 Alessandro Colombi , Mario Beraha , Amichai Painsky , Stefano Favaro

Approximating integrals is a fundamental task in probability theory and statistical inference, and their applied fields of signal processing, and Bayesian learning, as soon as expectations over probability distributions must be computed…

Statistics Theory · Mathematics 2026-05-06 Solal Martin , Emilie Chouzenoux , Victor Elvira