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When developing clinical prediction models, it can be challenging to balance between global models that are valid for all patients and personalized models tailored to individuals or potentially unknown subgroups. To aid such decisions, we…

Few studies have linked specific sources of ambient particulate matter smaller than 2.5 $\mu$m (PM2.5) and asthma. In this study, we estimated the contributions of specific sources to PM2.5 and examined their association with daily asthma…

Frequently during its lifetime a human organism is subjected to the acoustical and similar to them vibrating impacts. Under the certain conditions such influence may cause physiological changes in the organs functioning. Thus the study of…

Biological Physics · Physics 2007-12-27 A. S. Kholodov , S. S. Simakov , A. A. Nadolsky , A. N. Shushlebin

The risk of indoor airborne transmission among co-located individuals is generally non-uniform, which remains a critical challenge for public health modelling. Thus, we present CompARE, an integrated risk assessment framework for indoor…

Medicine is moving from a curative discipline to a preventative discipline relying on personalised and precise treatment plans. The complex and multi level pathophysiological patterns of most diseases require a systemic medicine approach…

Computational Engineering, Finance, and Science · Computer Science 2020-07-21 Pietro Barbiero , Pietro Lió

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

Advances in healthcare and in the quality of life significantly increase human life expectancy. With the ageing of populations, new un-faced challenges are brought to science. The human body is naturally selected to be well-functioning…

Artificial Intelligence · Computer Science 2016-07-21 Grazziela P. Figueredo , Peer-Olaf Siebers , Uwe Aickelin , Amanda Whitbrook , Jonathan M. Garibaldi

Health insurance companies cover half of the United States population through commercial employer-sponsored health plans and pay 1.2 trillion US dollars every year to cover medical expenses for their members. The actuary and underwriter…

Main objective of this study is to introduce an expert system-based mHealth application that takes Artificial Intelligence support by considering previously introduced solutions from the literature and employing possible requirements for a…

Human-Computer Interaction · Computer Science 2021-08-23 Ismail Ali Afrah , Utku Kose

Assessing and managing the impact of large-scale epidemics considering only the individual risk and severity of the disease is exceedingly difficult and could be extremely expensive. Economic consequences, infrastructure and service…

Physics and Society · Physics 2019-12-11 Emanuele Massaro , Alexander Ganin , Nicola Perra , Igor Linkov , Alessandro Vespignani

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

Optimization and Control · Mathematics 2015-05-06 Robin J. Evans , Musa Mammadov

One of the recently proposed strategies in health systems is providing services to patients at home, improving the service quality, besides reducing the health system costs. In the real world, some services, such as biological tests or…

Optimization and Control · Mathematics 2022-05-03 Pouria Khodabandeh , Vahid Kayvanfar , Majid Rafiee , Frank Werner

Alzheimer's Disease (AD) is the most common type of dementia, comprising 60-80% of cases. There were an estimated 5.8 million Americans living with Alzheimer's dementia in 2019, and this number will almost double every 20 years. The total…

Information Retrieval · Computer Science 2020-05-21 Krishna B. Soundararajan , Sunyang Fu , Luke A. Carlson , Rebecca A. Smith , David S. Knopman , Hongfang Liu , Yanshan Wang

Approximately over 50 million people worldwide suffer from epilepsy. Traditional diagnosis of epilepsy relies on tedious visual screening by highly trained clinicians from lengthy EEG recording that contains the presence of seizure (ictal)…

Artificial Intelligence · Computer Science 2009-04-27 Forrest Sheng Bao , Jue-Ming Gao , Jing Hu , Donald Y. -C. Lie , Yuanlin Zhang , K. J. Oommen

Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…

Machine Learning · Computer Science 2017-05-24 Aniruddh Raghu , Matthieu Komorowski , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Locomotor system disorders affect a vast majority of people at some time in their life bringing pain, functional limitations, social and economic implications. Modern medicine cannot offer prevention and effective treatment for most chronic…

Tissues and Organs · Quantitative Biology 2013-03-13 Zoja Medjanik , Lyudmila Popova , Sergiy Popov

Cardiovascular diseases and heart failures in particular are the main cause of non-communicable disease mortality in the world. Constant patient monitoring enables better medical treatment as it allows practitioners to react on time and…

Artificial Intelligence · Computer Science 2021-04-21 Kordian Gontarska , Weronika Wrazen , Jossekin Beilharz , Robert Schmid , Lauritz Thamsen , Andreas Polze

Dengue, which affects millions of people each year, is one of the most common diseases transmitted by infected \textit{Aedes aegypti} mosquitoes. In the Philippines, the annual economic cost of dengue infections is estimated at around PHP…

Optimization and Control · Mathematics 2026-01-19 Kyrho Corum , Renier Mendoza , Victoria May P. Mendoza , Arrianne Crystal Velasco

Using SimPy and Discrete Event Simulation we have observed the different model responses of a system consisting of a hospital and people getting sick/healing under different initial conditions. In our model, each independent person can get…

Numerical Analysis · Mathematics 2022-03-25 Dincer Atasoy

This paper presents a cloud-connected indoor air quality sensor system that can be deployed to patients' homes to study personal microenvironmental exposure for asthma research and management. The system consists of multiple compact sensor…

Quantitative Methods · Quantitative Biology 2021-01-12 Quan Dong , Baichen Li , R. Scott Downen , Nam Tran , Elizabeth Chorvinsky , Dinesh K. Pillai , Mona E. Zaghloul , Zhenyu Li
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