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Single-shot volumetric fluorescence (SVF) imaging offers a significant advantage over traditional imaging methods that require scanning across multiple axial planes as it can capture biological processes with high temporal resolution. The…

We introduce a novel framework for upsampled Point Spread Function (PSF) modeling using pixel-level Bayesian inference. Accurate PSF characterization is critical for precision measurements in many fields including: weak lensing, astrometry,…

Instrumentation and Methods for Astrophysics · Physics 2025-11-26 Connor Stone , Ronan Legin , Alexandre Adam , Nikolay Malkin , Gabriel Missael Barco , Laurence Perreaul-Levasseur , Yashar Hezaveh

Point-spread-function (PSF) engineering is a well-established computational imaging technique that uses phase masks and other optical elements to embed extra information (e.g., depth) into the images captured by conventional CMOS image…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Sachin Shah , Matthew Albert Chan , Haoming Cai , Jingxi Chen , Sakshum Kulshrestha , Chahat Deep Singh , Yiannis Aloimonos , Christopher Metzler

Monocular depth estimation is still an open challenge due to the ill-posed nature of the problem at hand. Deep learning based techniques have been extensively studied and proved capable of producing acceptable depth estimation accuracy even…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Mazen Mel , Muhammad Siddiqui , Pietro Zanuttigh

This Point spread function (PSF) plays a crucial role in many computational imaging applications, such as shape from focus/defocus, depth estimation, and fluorescence microscopy. However, the mathematical model of the defocus process is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Renzhi He , Yan Zhuang , Boya Fu , Fei Liu

Point-spread-function (PSF) engineering is a powerful computational imaging techniques wherein a custom phase mask is integrated into an optical system to encode additional information into captured images. Used in combination with deep…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Sachin Shah , Sakshum Kulshrestha , Christopher A. Metzler

The point spread function (PSF) is fundamental to any type of microscopy, most importantly so for single-molecule localization techniques, where the exact PSF shape is crucial for precise molecule localization at the nanoscale. However,…

The point-spread function (PSF) of an imaging system describes the response of the system to a point source. Accurately determining the PSF enables one to correct for the combined effects of focussing and scattering within the imaging…

Instrumentation and Methods for Astrophysics · Physics 2022-11-01 Stefan Johann Hofmeister , Michael Hahn , Daniel Wolf Savin

Based on point spread function (PSF) engineering and astigmatism due to a pair of cylindrical lenses, a novel compressed imaging mechanism is proposed to achieve single-shot incoherent 3D imaging. The speckle-like PSF of the imaging system…

Optics · Physics 2021-05-24 Qiong Gao , Weidong Qu , Ming Shao , Wei Liu , Xiangzheng Cheng

A long-standing challenge in multiple-particle-tracking is the accurate and precise 3D localization of individual particles at close proximity. One established approach for snapshot 3D imaging is point-spread-function (PSF) engineering, in…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Elias Nehme , Boris Ferdman , Lucien E. Weiss , Tal Naor , Daniel Freedman , Tomer Michaeli , Yoav Shechtman

Accurate and fast 3D imaging of specular surfaces still poses major challenges for state-of-the-art optical measurement principles. Frequently used methods, such as phase-measuring deflectometry (PMD) or shape-from-polarization (SfP), rely…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Jiazhang Wang , Oliver Cossairt , Florian Willomitzer

Simulated images are essential in algorithm development and instrument testing for optical telescopes. During real observations, images obtained by optical telescopes are affected by spatially variable point spread functions (PSFs), a…

Instrumentation and Methods for Astrophysics · Physics 2025-02-17 Zeyu Bai , Peng Jia , Jiameng Lv , Xiang Zhang , Wennan Xiang , Lin Nie

The key features of the MATPHOT algorithm for precise and accurate stellar photometry and astrometry using discrete Point Spread Functions are described. A discrete Point Spread Function (PSF) is a sampled version of a continuous PSF which…

Astrophysics · Physics 2009-11-11 Kenneth J. Mighell

Point Spread Function (PSF) modeling is a central part of any astronomy data analysis relying on measuring the shapes of objects. It is especially crucial for weak gravitational lensing, in order to beat down systematics and allow one to…

Instrumentation and Methods for Astrophysics · Physics 2015-05-30 Joel Bergé , Sedona Price , Adam Amara , Jason Rhodes

Rotating-PSF imaging via spiral phase engineering can localize point sources over large focal depths in a snapshot mode. This letter presents a full vector-field analysis of the rotating-PSF imager that quantifies the PSF signature of the…

Optics · Physics 2014-12-22 Zhixian Yu , Sudhakar Prasad

Localization microscopy is an imaging technique in which the positions of individual nanoscale point emitters (e.g. fluorescent molecules) are determined at high precision from their images. This is the key ingredient in…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Elias Nehme , Daniel Freedman , Racheli Gordon , Boris Ferdman , Lucien E. Weiss , Onit Alalouf , Reut Orange , Tomer Michaeli , Yoav Shechtman

We describe the change of the spatial distribution of the state of polarisation occurring during two-dimensional imaging through a multilayer and in particular through a layered metallic flat lens. Linear or circular polarisation of…

Polarization-based vision has gained increasing attention for providing richer physical cues beyond RGB images. While achieving single-shot capture is highly desirable for practical applications, existing Division-of-Focal-Plane (DoFP)…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Shuangfan Zhou , Chu Zhou , Heng Guo , Youwei Lyu , Boxin Shi , Zhanyu Ma , Imari Sato

Point spread function (PSF) engineering has been pivotal in the remarkable progress made in high-resolution imaging in the last decades. However, the diversity in PSF structures attainable through existing engineering methods is limited.…

Optics · Physics 2025-06-10 Md Sadman Sakib Rahman , Aydogan Ozcan

We present the development of a data-driven, AI-based model of the Point Spread Function (PSF) that achieves higher accuracy than the current state-of-the-art approach, "PSF in the Full Field-of-View'' (PIFF). PIFF is widely used in leading…

Instrumentation and Methods for Astrophysics · Physics 2026-02-18 Dayana Andrea Henao Arbeláez , Pierre-François Léget , Andrés Alejandro Plazas Malagón
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